DNA-mediated gene transfer: recombination between cotransferred DNA sequences and recovery of recombinants in a plasmid.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Nucleotide sequence of the rightward operator of phage lambda.

1975 • 2,068 citations

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

Preparative and analytical purification of DNA from agarose.

1979 • 1,585 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Prolonged incubation in calcium chloride improves the competence of Escherichia coli cells

1979 • 1,454 citations

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

1977 • 1,411 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

A general model for genetic recombination.

1975 • 890 citations

Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences

1981 • 657 citations

The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene

1980 • 556 citations

Genetic studies of the lac repressor

1978 • 517 citations

Genetic and physical linkage of exogenous sequences in transformed cells

1980 • 486 citations

Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1.

1981 • 388 citations

The transfer and stable integration of the HSV thymidine kinase gene into mouse cells

1978 • 382 citations

The organization of histones and DNA in chromatin: Evidence for an arginine-rich histone kernel

1976 • 371 citations

Genetic Recombination: Strand Transfer and Mismatch Repair

1978 • 270 citations

Transfer of the gene for thymidine kinase to thymidine kinase-deficient human cells by purified herpes simplex viral DNA.

1977 • 246 citations

Cloning of the active thymidine kinase gene of herpes simplex virus type 1 in Escherichia coli K-12.

1979 • 238 citations

A new method for the purification and identification of covalently closed circular DNA molecules

1978 • 210 citations

Isolation of the chicken thymidine kinase gene by plasmid rescue

1980 • 208 citations

Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of herpes simplex type 1 virus

1979 • 189 citations

Recombination between short DNA homologies causes tandem duplication

1981 • 184 citations

Biochemical transformation of mouse cells by fragments of herpes simplex virus DNA

1977 • 180 citations

Integration and excision of SV40 DNA from the chromosome of a transformed cell

1980 • 169 citations

Expression of the herpes thymidine kinase gene in Xenopus laevis oocytes: an assay for the study of deletion mutants constructed in vitro

1980 • 152 citations

Loss of integrated viral DNA sequences in polyoma-transformed cells is associated with an active viral A function

1979 • 117 citations

Recombination activities of E. coli RecA protein

1981 • 87 citations

Polyoma large T antigen regulates the integration of viral DNA sequences into the genome of transformed cells

1981 • 71 citations

Indiscriminate recombination in simian virus 40-infected monkey cells.

1980 • 70 citations

Nucleosomal packaging of the thymidine kinase gene of herpes simplex virus transferred into mouse cells: an actively expressed single-copy gene.

1980 • 53 citations

Integration sites and sequence arrangement of SV40 DNA in a homogeneous series of transformed rat fibroblast lines

1980 • 37 citations