Altered lipid raft–associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus

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Induction of Dendritic Cell Differentiation by IFN-α in Systemic Lupus Erythematosus

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CD45: A Critical Regulator of Signaling Thresholds in Immune Cells

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LAT Palmitoylation

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Cbl-b regulates the CD28 dependence of T-cell activation

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Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization

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Location is Everything: Lipid Rafts and Immune Cell Signaling

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Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains (Pag), a Novel Ubiquitously Expressed Transmembrane Adaptor Protein, Binds the Protein Tyrosine Kinase Csk and Is Involved in Regulation of T Cell Activation

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The role of lipid rafts in T cell antigen receptor (TCR) signalling

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S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

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Cholesterol depletion disrupts lipid rafts and modulates the activity of multiple signaling pathways in T lymphocytes

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TCR signal initiation machinery is pre-assembled and activated in a subset of membrane rafts

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Cbl-b Is a Negative Regulator of Receptor Clustering and Raft Aggregation in T Cells

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Proximal protein tyrosine kinases in immunoreceptor signaling

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Displacement of Linker for Activation of T Cells from the Plasma Membrane Due to Redox Balance Alterations Results in Hyporesponsiveness of Synovial Fluid T Lymphocytes in Rheumatoid Arthritis

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Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases

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Insights into Src kinase functions: structural comparisons

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Negative regulation of Lck by Cbl ubiquitin ligase

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Lipid Raft Heterogeneity in Human Peripheral Blood T Lymphoblasts: A Mechanism for Regulating the Initiation of TCR Signal Transduction

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Immune cell signaling defects in lupus: activation, anergy and death

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Regulatory Defects in Cbl and Mitogen-Activated Protein Kinase (Extracellular Signal-Related Kinase) Pathways Cause Persistent Hyperexpression of CD40 Ligand in Human Lupus T Cells

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Increased ubiquitination and reduced expression of LCK in T lymphocytes from patients with systemic lupus erythematosus

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Cbl and Cbl-b in T-cell regulation

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Dynamic Association of CD45 with Detergent-Insoluble Microdomains in T Lymphocytes

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Molecular controls of antigen receptor clustering and autoimmunity

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Abnormal expression of various molecular forms and distribution of T cell receptor ? chain in patients with systemic lupus erythematosus

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T-cell anergy and altered T-cell receptor signaling: effects on autoimmune disease

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Impaired T cell capping and receptor regeneration in active systemic lupus erythematosus. Evidence for a disorder intrinsic to the T lymphocyte.

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The Lck SH3 Domain Negatively Regulates Localization to Lipid Rafts through an Interaction with c-Cbl

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Selective interaction of LAT (linker of activated T cells) with the open-active form of Lck in lipid rafts reveals a new mechanism for the regulation of Lck in T cells

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Lck plays a critical role in Ca2+ mobilization and CD28 costimulation in mature primary T cells

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A human anti-dsDNA monoclonal antibody caused hyaline thrombi formation in kidneys of ‘leaky’ SCID mice

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Spontaneous antibody-secreting cells against DNA and common environmental antigens in systemic lupus erythematosus

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