Cbl-b Is a Negative Regulator of Receptor Clustering and Raft Aggregation in T Cells

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

1999 • 3,025 citations

Three-dimensional segregation of supramolecular activation clusters in T cells

1998 • 2,316 citations

A Cell Culture Model for T Lymphocyte Clonal Anergy

1990 • 1,894 citations

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

1995 • 1,079 citations

The Tyrosine Kinase Negative Regulator c-Cbl as a RING-Type, E2-Dependent Ubiquitin-Protein Ligase

1999 • 1,045 citations

Ubiquitin Ligase Activity and Tyrosine Phosphorylation Underlie Suppression of Growth Factor Signaling by c-Cbl/Sli-1

1999 • 1,000 citations

The Immunological Synapse

2001 • 987 citations

T Lymphocyte Costimulation Mediated by Reorganization of Membrane Microdomains

1999 • 964 citations

JNK is involved in signal integration during costimulation of T lymphocytes

1994 • 929 citations

Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin-2 Receptor β

1995 • 868 citations

Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein

2000 • 739 citations

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

2000 • 656 citations

A Receptor/Cytoskeletal Movement Triggered by Costimulation During T Cell Activation

1998 • 625 citations

Cbl-b regulates the CD28 dependence of T-cell activation

2000 • 607 citations

Selective modulation of protein kinase C-Θ during T-cell activation

1997 • 558 citations

Wiskott-Aldrich Syndrome Protein-Deficient Mice Reveal a Role for WASP in T but Not B Cell Activation

1998 • 494 citations

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1998 • 420 citations

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

1998 • 403 citations

Making the T Cell Receptor Go the Distance: A Topological View of T Cell Activation

1997 • 399 citations

Costimulatory regulation of T cell function

1999 • 391 citations

Tissue Hyperplasia and Enhanced T-Cell Signalling via ZAP-70 in c-Cbl-Deficient Mice

1998 • 371 citations

Antigen Receptor–Induced Activation and Cytoskeletal Rearrangement Are Impaired in Wiskott-Aldrich Syndrome Protein–Deficient Lymphocytes

1999 • 367 citations

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

1998 • 343 citations

A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

1997 • 285 citations

Engagement of GPI-Linked CD48 Contributes to TCR Signals and Cytoskeletal Reorganization

1998 • 278 citations

The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor α

1998 • 257 citations

The Actin Cytoskeleton and Lymphocyte Activation

1999 • 218 citations

The Cbl protooncoprotein: a negative regulator of immune receptor signal transduction

1999 • 137 citations

cbl-3: a new mammalian cbl family protein

1999 • 117 citations

Susceptibility to lymphocytic choriomeningitis virus isolates correlates directly with early and high cytotoxic T cell activity, as well as with footpad swelling reaction, and all three are regulated by H-2D.

1985 • 102 citations

Regulation of p21rac Activation in Human Neutrophils

1999 • 82 citations