Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

1996 • 5,498 citations

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1995 • 5,143 citations

Cellular survival: a play in three Akts

1999 • 4,229 citations

Mechanism of activation of protein kinase B by insulin and IGF-1.

1996 • 2,965 citations

Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor

1999 • 2,386 citations

Peroxynitrite formation from macrophage-derived nitric oxide

1992 • 1,118 citations

Phosphorylation and Regulation of Raf by Akt (Protein Kinase B)

1999 • 1,084 citations

Differentiation Stage-Specific Inhibition of the Raf-MEK-ERK Pathway by Akt

1999 • 762 citations

Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

1998 • 612 citations

Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents.

1996 • 523 citations

The PI3K‒PDK1 connection: more than just a road to PKB

2000 • 503 citations

Epidermal Growth Factor Receptor-dependent Akt Activation by Oxidative Stress Enhances Cell Survival

2000 • 455 citations

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2

1999 • 440 citations

The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase.

1996 • 419 citations

The basic chemistry of nitrogen monoxide and peroxynitrite

1998 • 345 citations

Peroxynitrite disables the tyrosine phosphorylation regulatory mechanism: Lymphocyte-specific tyrosine kinase fails to phosphorylate nitrated cdc2(6-20)NH2 peptide.

1996 • 341 citations

Peroxynitrite Inhibits T Lymphocyte Activation and Proliferation by Promoting Impairment of Tyrosine Phosphorylation and Peroxynitrite-Driven Apoptotic Death

1999 • 307 citations

Protection against peroxynitrite

1999 • 304 citations

Activation of protein kinase B (Akt/RAC‐protein kinase) by cellular stress and its association with heat shock protein Hsp27

1997 • 270 citations

Mechanism of Protein Kinase B Activation by Cyclic AMP-Dependent Protein Kinase

1999 • 262 citations

Mitogen‐activated protein kinase (p38‐, JNK‐, ERK‐) activation pattern induced by extracellular and intracellular singlet oxygen and UVA

1999 • 232 citations

Peroxynitrite‐induced thymocyte apoptosis: the role of caspases and poly (ADP‐ribose) synthetase (PARS) activation

1998 • 210 citations

Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress

1998 • 209 citations

Peroxynitrite: reactive, invasive and enigmatic

1999 • 209 citations

[27] Syntheses of peroxynitrite: To go with the flow or on solid grounds?

1996 • 206 citations

Rapid and Irreversible Inactivation of Protein Tyrosine Phosphatases PTP1B, CD45, and LAR by Peroxynitrite

1999 • 197 citations

The Physiological and Pathological Chemistry of Nitric Oxide

1996 • 168 citations

Peroxynitrite modulates tyrosine‐dependent signal transduction pathway of human erythrocyte band 3

1997 • 168 citations

Activation pattern of mitogen‐activated protein kinases elicited by peroxynitrite: attenuation by selenite supplementation

1999 • 126 citations

Mitogen-Activated Protein Kinase Pathway Mediates Peroxynitrite-Induced Apoptosis in Human Dopaminergic Neuroblastoma SH-SY5Y Cells

1999 • 124 citations

Peroxynitrite Induces Covalent Dimerization of Epidermal Growth Factor Receptors in A431 Epidermoid Carcinoma Cells

1998 • 100 citations

Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease

1998 • 96 citations

Evidence for peroxynitrite as an oxidative stress-inducing compound of aqueous cigarette smoke fractions

1997 • 82 citations

Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: a link to apoptosis

1999 • 80 citations

Peroxynitrite modulates MnSOD gene expression in lung epithelial cells

1998 • 33 citations

[Structure and function of protein tyrosine phosphatases].

1998 • 23 citations