Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

1989 • 931 citations

Firefly Luciferase Gene: Structure and Expression in Mammalian Cells

1987 • 924 citations

Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun

1989 • 698 citations

Erythroleukemic Differentiation

1978 • 694 citations

A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome

1984 • 674 citations

fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen.

1988 • 518 citations

Fos and Jun bind cooperatively to the AP-1 site: reconstitution in vitro.

1988 • 511 citations

Characterization of junD: a new member of the jun proto-oncogene family.

1989 • 492 citations

Megakaryocytic and erythrocytic lineages share specific transcription factors

1990 • 446 citations

Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice

1990 • 364 citations

The human beta-globin gene 3' enhancer contains multiple binding sites for an erythroid-specific protein.

1988 • 362 citations

A dominant control region from the human β-globin locus conferring integration site-independent gene expression

1989 • 346 citations

Developmental regulation of β-globin gene switching

1988 • 328 citations

Two tissue-specific factors bind the erythroid promoter of the human porphobilinogen deaminase gene

1989 • 326 citations

Definition of the minimal requirements within the human beta-globin gene and the dominant control region for high level expression.

1990 • 322 citations

Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells.

1990 • 301 citations

Human gamma- to beta-globin gene switching in transgenic mice.

1990 • 291 citations

An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes.

1989 • 280 citations

Cis- and trans-acting elements involved in the regulation of the erythroid promoter of the human porphobilinogen deaminase gene.

1989 • 272 citations

A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice.

1989 • 269 citations

Viral and cellular fos proteins are complexed with a 39,000-dalton cellular protein.

1985 • 249 citations

Molecular analysis of the human beta-globin locus activation region.

1989 • 218 citations

The human beta-globin promoter; nuclear protein factors and erythroid specific induction of transcription.

1988 • 211 citations

Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice.

1987 • 202 citations

A 3′ enhancer is required for temporal and tissue-specific transcriptional activation of the chicken adult β-globin gene

1986 • 192 citations

Embryonic erythroid differentiation in the human leukemic cell line K562.

1981 • 183 citations

The human beta-globin gene contains multiple regulatory regions: identification of one promoter and two downstream enhancers.

1988 • 175 citations

The human β-globin gene contains a downstream developmental specific enhancer

1987 • 167 citations

Regulated gene expression in transfected primary chicken erythrocytes.

1986 • 144 citations

Inducible transcription of five globin genes in K562 human leukemia cells.

1983 • 138 citations

An enhancer element lies 3′ to the human A gamma globin gene.

1987 • 135 citations

A 3' enhancer contributes to the stage-specific expression of the human beta-globin gene.

1987 • 128 citations

Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site.

1989 • 122 citations

Mutational analysis of the chicken beta-globin enhancer reveals two positive-acting domains.

1988 • 120 citations

fra-1: a Serum-Inducible, Cellular Immediate-Early Gene That Encodes a Fos-Related Antigen

1988 • 115 citations

Nuclear Proteins That Bind the Human ϒ-Globin Gene Promoter: Alterations in Binding Produced by Point Mutations Associated with Hereditary Persistence of Fetal Hemoglobin

1988 • 112 citations

Developmental Regulation of Topoisomerase II Sites and DNase I-Hypersensitive Sites in the Chicken β-Globin Locus

1990 • 108 citations

The effects of HPFH mutations in the human γ-globin promoter on binding of ubiquitous and erythroid specific nuclear factors

1988 • 91 citations

A 46 base pair enhancer sequence within the locus activating region is required for induced expression of the gamma-globin gene during erythroid differentiation

1990 • 79 citations

An erythroid specific nuclear factor binding to the proximal CACCC box of the β-globin gene promoter

1988 • 72 citations

Viral and Cellular fos Proteins Are Complexed with a 39,000-Dalton Cellular Protein

1985 • 58 citations

Nuclear protein factors and erythroid transcription of the human A_γ-globin gene

1989 • 49 citations

Human globin gene promoter sequences are sufficient for specific expression of a hybrid gene transfected into tissue culture cells.

1987 • 42 citations

Activation of the human beta-globin promoter in K562 cells by DNA sequences 5' to the fetal gamma- or embryonic zeta-globin genes.

1987 • 31 citations