Long-Term Correction of Phagocyte NADPH Oxidase Activity by Retroviral-Mediated Gene Transfer in Murine X-Linked Chronic Granulomatous Disease

A safe packaging line for gene transfer: separating viral genes on two different plasmids

1988 • 1,118 citations

Mouse model of X–linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production

1995 • 920 citations

Versatile retroviral vectors for potential use in gene therapy.

1994 • 690 citations

Clonal and systemic analysis of long-term hematopoiesis in the mouse.

1990 • 577 citations

The p47phox mouse knock-out model of chronic granulomatous disease.

1995 • 487 citations

Mutations in the X-linked and autosomal recessive forms of chronic granulomatous disease

1996 • 424 citations

The Molecular Basis of Blood Diseases

1994 • 370 citations

Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease

1997 • 347 citations

Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b.

1988 • 317 citations

Anion Exchanger 1 (Band 3) Is Required to Prevent Erythrocyte Membrane Surface Loss but Not to Form the Membrane Skeleton

1996 • 278 citations

Incidence, severity, and prevention of infections in chronic granulomatous disease

1989 • 272 citations

Improved Gene Transfer Into Baboon Marrow Repopulating Cells Using Recombinant Human Fibronectin Fragment CH-296 in Combination With Interleukin-6, Stem Cell Factor, FLT-3 Ligand, and Megakaryocyte Growth and Development Factor

1998 • 262 citations

Life span of multipotential hematopoietic stem cells in vivo.

1990 • 228 citations

Treatment of genetic defects in hematopoietic cell function by gene transfer

1991 • 225 citations

In vivo selection of retrovirally transduced hematopoietic stem cells

1998 • 214 citations

Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phox.

1993 • 213 citations

Embryonic stem cell virus, a recombinant murine retrovirus with expression in embryonic stem cells.

1990 • 203 citations

Gp91 ^phox is the heme binding subunit of the superoxide-generating NADPH oxidase

1998 • 198 citations

Blood and blood formation.

1966 • 179 citations

Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus.

1992 • 167 citations

Efficient Retroviral-Mediated Gene Transfer to Human Cord Blood Stem Cells With In Vivo Repopulating Potential

1998 • 161 citations

Biosynthesis of the Phagocyte NADPH Oxidase Cytochromeb 558

1997 • 156 citations

[59] Kinetic microplate assay for superoxide production by neutrophils and other phagocytic cells

1990 • 151 citations

An internal ribosomal entry mechanism promotes translation of murine leukemia virus gag polyprotein precursors

1995 • 140 citations

Effects of recombinant human interleukin-11 on hematopoietic reconstitution in transplant mice: acceleration of recovery of peripheral blood neutrophils and platelets

1993 • 139 citations

Enhanced Host Defense After Gene Transfer in the Murine p47phox-Deficient Model of Chronic Granulomatous Disease

1997 • 133 citations

The Respiratory Burst Oxidase and the Molecular Genetics of Chronic Granulomatous Disease

1993 • 130 citations

Retroviral-Mediated Gene Transfer of gp91phox Into Bone Marrow Cells Rescues Defect in Host Defense Against Aspergillus fumigatus in Murine X-Linked Chronic Granulomatous Disease

1997 • 124 citations

Molecular Genetics of Chronic Granulomatous Disease

1989 • 114 citations

Use of the green fluorescent protein as a marker to identify and track genetically modified hematopoietic cells

1998 • 110 citations

Retroviral-Mediated Gene Transfer of gp91phox Into Bone Marrow Cells Rescues Defect in Host Defense Against Aspergillus fumigatus in Murine X-Linked Chronic Granulomatous Disease

1997 • 103 citations

Primary inherited defects in neutrophil function: etiology and treatment.

1997 • 97 citations

Comparison of Normal Blood Picture of Young Adults from 18 Inbred Strains of Mice

1951 • 95 citations

Prognosis of chronic granulomatous disease.

1990 • 93 citations

Sustained Gene Expression in Retrovirally Transduced, Engrafting Human Hematopoietic Stem Cells and Their Lympho-Myeloid Progeny

1998 • 88 citations

Peripheral blood progenitors as a target for genetic correction of p47phox-deficient chronic granulomatous disease.

1993 • 85 citations

CD34+ peripheral blood progenitors as a target for genetic correction of the two flavocytochrome b558 defective forms of chronic granulomatous disease

1994 • 83 citations

X-linked Inheritance in Females with Chronic Granulomatous Disease

1980 • 83 citations

Sustained High-Level Reconstitution of the Hematopoietic System by Preselected Hematopoietic Cells Expressing a Transduced Cell-Surface Antigen

1997 • 80 citations

Progenitor cell hyperplasia with rare development of myeloid leukemia in interleukin 11 bone marrow chimeras.

1993 • 65 citations

Cloning of murine gp91phox cDNA and functional expression in a human X- linked chronic granulomatous disease cell line

1996 • 65 citations

Thrombopoietic potential and serial repopulating ability of murine hematopoietic stem cells constitutively expressing interleukin 11.

1996 • 62 citations

High-level reconstitution of respiratory burst activity in a human X- linked chronic granulomatous disease (X-CGD) cell line and correction of murine X-CGD bone marrow cells by retroviral-mediated gene transfer of human gp91phox

1996 • 59 citations

The management of chronic granulomatous disease

1993 • 59 citations

X-linked chronic granulomatous disease: correction of NADPH oxidase defect by retrovirus-mediated expression of gp91-phox

1993 • 50 citations

Retrovirus-mediated reconstitution of respiratory burst activity in X- linked chronic granulomatous disease cells

1994 • 41 citations

Recurrent severe infections in a girl with apparently variable expression of mosaicism for chronic granulomatous disease

1985 • 40 citations

Clonal Analysis of Hematopoietic Stem Cell Development In Vivo

1992 • 33 citations

Hematological Changes in Aging Male C57BL/6 Jax Mice

1964 • 19 citations

Biology of the Laboratory Mouse

1942 • 15 citations

GENE THERAPY FOR CONGENITAL IMMUNODEFICIENCY DISEASES

1996 • 11 citations