Use of the green fluorescent protein as a marker to identify and track genetically modified hematopoietic cells

Green Fluorescent Protein as a Marker for Gene Expression

1994 • 6,572 citations

Gene-marking to trace origin of relapse after autologous bone-marrow transplantation

1993 • 949 citations

Gene Therapy in Peripheral Blood Lymphocytes and Bone Marrow for ADA ⁻ Immunodeficient Patients

1995 • 846 citations

Chemical structure of the hexapeptide chromophore of the Aequorea green-fluorescent protein

1993 • 648 citations

A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells

1996 • 624 citations

Engraftment of gene–modified umbilical cord blood cells in neonates with adenosine deaminase deficiency

1995 • 622 citations

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors

1985 • 598 citations

T–cell mediated rejection of gene–modified HIV–specific cytotoxic T lymphocytes in HIV–infected patients

1996 • 581 citations

Selection of Drug-Resistant Bone Marrow Cells in Vivo After Retroviral Transfer of Human MDR 1

1992 • 500 citations

Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation

1995 • 496 citations

Optimized Codon Usage and Chromophore Mutations Provide Enhanced Sensitivity with the Green Fluorescent Protein

1996 • 435 citations

In Vivo Transfer of GPI-Linked Complement Restriction Factors from Erythrocytes to the Endothelium

1995 • 254 citations

Peripheral blood lymphocytes as target cells of retroviral vector- mediated gene transfer

1994 • 246 citations

Retroviral-Mediated Transfer of the Green Fluorescent Protein Gene Into Murine Hematopoietic Cells Facilitates Scoring and Selection of Transduced Progenitors In Vitro and Identification of Genetically Modified Cells In Vivo

1997 • 230 citations

Self-contained, tetracycline-regulated retroviral vector system for gene delivery to mammalian cells

1996 • 206 citations

Use of green fluorescent protein variants to monitor gene transfer and expression in mammalian cells

1996 • 171 citations

Transfer and expression of the human multiple drug resistance gene in human CD34+ cells

1994 • 137 citations

A GFP reporter system to assess gene transfer and expression in human hematopoietic progenitor cells

1997 • 119 citations

Green fluorescent protein as a marker in transgenic mice

1995 • 116 citations

Selection of retrovirally transduced hematopoietic cells using CD24 as a marker of gene transfer

1994 • 108 citations

A knock-out model of paroxysmal nocturnal hemoglobinuria: Pig-a(-) hematopoiesis is reconstituted following intercellular transfer of GPI-anchored proteins.

1996 • 105 citations

Sustained High-Level Reconstitution of the Hematopoietic System by Preselected Hematopoietic Cells Expressing a Transduced Cell-Surface Antigen

1997 • 80 citations

Gene Transfer to Hematopoietic Cells

1996 • 79 citations

Rapid and efficient selection of human hematopoietic cells expressing murine heat-stable antigen as an indicator of retroviral-mediated gene transfer

1996 • 78 citations

High-Titer Retroviral Vectors Containing the Enhanced Green Fluorescent Protein Gene for Efficient Expression in Hematopoietic Cells

1997 • 76 citations

Gene Transfer into Hematopoietic Stem Cells of Nonhuman Primates

1996 • 64 citations

Enhanced Green Fluorescent Protein as Selectable Marker of Retroviral-Mediated Gene Transfer in Immature Hematopoietic Bone Marrow Cells

1997 • 64 citations

High-efficiency retroviral vector mediated gene transfer into human peripheral blood CD4+ T lymphocytes.

1996 • 61 citations

Production of genetically stable high-titer retroviral vectors that carry a human gamma-globin gene under the control of the alpha-globin locus control region

1996 • 56 citations

Cell–surface markers for assessing gene transfer into human hematopoietic cells

1996 • 52 citations

Expression of HLA-DR antigen in human class II mutant B-cell lines by double infection with retrovirus vectors.

1987 • 31 citations

Gene transfer into hematopoietic cells

1997 • 31 citations

Retroviral mediated gene transfer into bone marrow progenitor cells: use of beta-galactosidase as a selectable marker

1990 • 27 citations

Transplantation and gene transfer of the human glucocerebrosidase gene into immunoselected primate CD34+Thy-1+ cells

1996 • 25 citations

15 The Hematopoietic System as a Target for Gene Therapy

1999 • 19 citations