Tissue Transglutaminase: A Candidate Effector Element of Physiological Cell Death

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Induction of apoptosis in fibroblasts by c-myc protein

1992 • 2,977 citations

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1991 • 2,127 citations

Mechanisms and Functions of Cell Death

1991 • 2,061 citations

HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

1993 • 1,822 citations

The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis

1988 • 1,496 citations

Programmed Cell Death and the Control of Cell Survival: Lessons from the Nervous System

1993 • 1,470 citations

Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

1993 • 1,387 citations

Apoptosis: Mechanisms and Roles in Pathology

1991 • 1,368 citations

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1989 • 1,159 citations

Apoptosis and Programmed Cell Death in Immunity

1992 • 1,105 citations

Transglutaminases: multifunctional cross‐linking enzymes that stabilize tissues

1991 • 999 citations

Programmed Death of T Cells in HIV-1 Infection

1992 • 932 citations

Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals.

1992 • 907 citations

Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis

1990 • 871 citations

Transglutaminases

1980 • 818 citations

The ɛ-(γ-Glutamyl)Lysine Crosslink and the Catalytic Role of Transglutaminases

1977 • 813 citations

Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis.

1992 • 689 citations

Premature p34 ^cdc2 Activation Required for Apoptosis

1994 • 568 citations

Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death).

1993 • 554 citations

Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis

1991 • 548 citations

Apoptotic cell death and tissue remodelling during mouse mammary gland involution

1992 • 536 citations

T Cell Deletion in High Antigen Dose Therapy of Autoimmune Encephalomyelitis

1994 • 530 citations

Terminal differentiation of cultured human epidermal cells

1977 • 521 citations

Induction and activation of tissue transglutaminase during programmed cell death

1987 • 467 citations

Induction of the TRPM-2 gene in cells undergoing programmed death.

1989 • 466 citations

Cell death by apoptosis and its protective role against disease

1992 • 439 citations

Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1.

1991 • 432 citations

Apoptosis: molecular mechanisms in programmed cell death.

1991 • 425 citations

Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen

1990 • 375 citations

The cytopathic effect of hiv is associated with apoptosis

1991 • 358 citations

Activation-induced cell death (apoptosis) of mature peripheral T lymphocytes

1993 • 314 citations

Development in the thymus: it takes two to tango

1993 • 281 citations

Cellular signalling in programmed cell death (apoptosis)

1990 • 255 citations

Apoptotic hepatocytes become insoluble in detergents and chaotropic agents as a result of transglutaminase action

1989 • 254 citations

Tissue Transglutaminase and Apoptosis: Sense and Antisense Transfection Studies with Human Neuroblastoma Cells

1994 • 253 citations

Isolation and characterization of cDNA clones to mouse macrophage and human endothelial cell tissue transglutaminases.

1991 • 250 citations

Expression of tissue transglutaminase in Balb-C 3T3 fibroblasts: effects on cellular morphology and adhesion.

1992 • 234 citations

Differential expression of tissue transglutaminase in human cells

1989 • 226 citations

Amino acid sequence of the a subunit of human factor XIII

1986 • 192 citations

The clearance of apoptotic cells in the liver is mediated by the asialoglycoprotein receptor

1992 • 185 citations

Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells.

1994 • 183 citations

The expression of "tissue" transglutaminase in two human cancer cell lines is related with the programmed cell death (apoptosis).

1991 • 183 citations

Amino acid sequence of guinea pig liver transglutaminase from its cDNA sequence

1988 • 181 citations

Expression of tissue transglutaminase in skeletal tissues correlates with events of terminal differentiation of chondrocytes.

1993 • 179 citations

Transglutaminases and the clotting of mammalian seminal fluids

1984 • 160 citations

Inhibition of CD4+ T cell function by the HIV envelope protein, gp120.

1988 • 160 citations

Lens transglutaminase and cataract formation.

1981 • 145 citations

?Tissue? transglutaminase is specifically expressed in neonatal rat liver cells undergoing apoptosis upon epidermal growth factor-stimulation

1991 • 138 citations

The deduced sequence of the novel protransglutaminase E (TGase3) of human and mouse

1993 • 117 citations

Apoptosis: a potential role for cytosolic transglutaminase and its importance in tumour progression

1991 • 96 citations

Free and protein-conjugated polyamines in mouse epidermal cells. Effect of high calcium and retinoic acid.

1988 • 94 citations

Purification and partial characterization of transglutaminase from Physarum polycephalum

1992 • 84 citations

Transglutaminase activity in human lymphocytes: early activation by phytomitogens.

1978 • 71 citations

Correlation between Induction of Lymphocyte Apoptosis and Prostaglandin E2 Production by Macrophages Infected with HIV

1993 • 66 citations

Human immunodeficiency virus-1 glycoproteins gp120 and gp160 specifically inhibit the CD3/T cell-antigen receptor phosphoinositide transduction pathway.

1990 • 63 citations

Activation of transglutaminase and production of protein-bound gamma-glutamylhistamine in stimulated mouse mast cells.

1985 • 52 citations

Degradation of cells dying by apoptosis leads to accumulation of ε(γ‐glutamyl)lysine isodipeptide in culture fluid and blood

1991 • 44 citations

Characterization of the transglutaminase-mediated large molecular weight polymer from rat liver; its relationship to apoptosis.

1993 • 43 citations

HIV‐1 gp120‐dependent induction of apoptosis in antigen‐specific human T cell clones is characterized by ‘tissue’ transglutaminase expression and prevented by cyclosporin A

1994 • 41 citations

Induction of Apoptosis in Thymocytes by Prostaglandin E2 In Vivo

1992 • 39 citations

Deoxyribonuclease II in apoptosis and the significance of intracellular acidification.

1994 • 38 citations

An involucrin-like protein in hepatocytes serves as a substrate for tissue transglutaminase during apoptosis.

1992 • 35 citations

Apoptotic DNA degradation: evidence for novel enzymes.

1994 • 32 citations

Cyclosporin A blocks calcium-dependent pathways of gene activation.

1991 • 28 citations

Is TCR β expression an essential event in early thymocyte development?

1993 • 27 citations

Human‐immunodeficiency‐virus transmembrane glycoprotein gp41 is an amino acceptor and donor substrate for transglutaminase in vitro

1993 • 21 citations

Abstract 535: Preclinical use of focal radiation and immune checkpoint blockade to improve therapeutic response in an immunologically cold tumor

2019 • 19 citations

Identification of promoter region of guinea pig liver transglutaminase gene

1993 • 13 citations

Macrophage-colony stimulating factor (M-CSF) stimulation induces cell death in HIV-infected human monocytes

1994 • 11 citations

Discussion

1992 • 6 citations