Apoptotic cell death and tissue remodelling during mouse mammary gland involution

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

The p53 tumour suppressor gene

1991 • 3,871 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1991 • 2,127 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

1984 • 1,586 citations

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death.

1984 • 1,441 citations

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

1991 • 1,301 citations

Induction of bcl-2 expression by epstein-barr virus latent membrane protein 1 protects infected B cells from programmed cell death

1991 • 1,195 citations

Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

1990 • 945 citations

A Role for a 70-Kilodalton Heat Shock Protein in Lysosomal Degradation of Intracellular Proteins

1989 • 932 citations

Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis

1990 • 871 citations

TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop

1990 • 756 citations

Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane

1989 • 700 citations

The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death

1990 • 533 citations

Activation of Epstein–Barr virus latent genes protects human B cells from death by apoptosis

1991 • 525 citations

Apoptosis-the molecular basis of cell death

1992 • 517 citations

Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation.

1990 • 485 citations

Induction and activation of tissue transglutaminase during programmed cell death

1987 • 467 citations

Induction of the TRPM-2 gene in cells undergoing programmed death.

1989 • 466 citations

Macrophage recognition of cells undergoing programmed cell death (apoptosis).

1985 • 460 citations

TGF-β1 inhibition of transin/stromelysin gene expression is mediated through a fos binding sequence

1990 • 444 citations

Mammary plasminogen activator: correlation with involution, hormonal modulation and comparison between normal and neoplastic tissue

1979 • 437 citations

Programmed cell death during regression of the MCF-7 human breast cancer following estrogen ablation.

1991 • 429 citations

Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid.

1989 • 412 citations

Cascade Induction of c-fos, c-myc, and Heat Shock 70K Transcripts during Regression of the Rat Ventral Prostate Gland

1988 • 355 citations

Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts.

1985 • 344 citations

Growth factors in the regulation of pericellular proteolysis: a review.

1989 • 342 citations

Cell death by apoptosis during involution of the lactating breast in mice and rats

1989 • 341 citations

Neoplastic Development

1970 • 295 citations

Coordinated regulation of apoptosis and cell proliferation by transforming growth factor beta 1 in cultured uterine epithelial cells.

1991 • 279 citations

Medial edge epithelium transforms to mesenchyme after embryonic palatal shelves fuse

1989 • 277 citations

Differential expression of TGF beta isoforms in murine palatogenesis

1990 • 257 citations

Apoptotic hepatocytes become insoluble in detergents and chaotropic agents as a result of transglutaminase action

1989 • 254 citations

Molecular cloning and characterization of the novel, human complement-associated protein, SP-40,40: a link between the complement and reproductive systems.

1989 • 243 citations

Effect of Transforming Growth Factor-β¹on Proliferation and Death of Rat Prostatic Cells*

1990 • 218 citations

Reduction of Naturally Occurring Motoneuron Death in Vivo by a Target-Derived Neurotrophic Factor

1988 • 213 citations

Distribution of myoepithelial cells and basement membrane proteins in the resting, pregnant, lactating, and involuting rat mammary gland.

1982 • 213 citations

Molecular cloning and expression of the mouse ornithine decarboxylase gene.

1984 • 211 citations

Cloning, nucleotide sequencing and expression of cDNAs encoding mouse urokinase‐type plasminogen activator

1985 • 201 citations

Atrophy and apoptosis in the cyclical human endometrium

1976 • 192 citations

The expression of "tissue" transglutaminase in two human cancer cell lines is related with the programmed cell death (apoptosis).

1991 • 183 citations

Analysis of the gene coding for the murine cellular tumour antigen p53.

1984 • 182 citations

Proteinases of the mammary gland: developmental regulation in vivo and vectorial secretion in culture

1991 • 181 citations

Rodent fibroblast tumours expressing human myc and ras genes: growth, metastasis and endogenous oncogene expression

1987 • 179 citations

TGF-β1-induced inhibition of mouse mammary ductal growth: Developmental specificity and characterization

1989 • 174 citations

Identification of a glucocorticoid-induced nuclease in thymocytes. A potential “lysis gene” product.

1987 • 167 citations

Cell-cell interactions promote mammary epithelial cell differentiation.

1985 • 143 citations

?Tissue? transglutaminase is specifically expressed in neonatal rat liver cells undergoing apoptosis upon epidermal growth factor-stimulation

1991 • 138 citations

Epidermal growth factor or serum stimulation of rat fibroblasts induces an elevation in mRNA levels for lactate dehydrogenase and other glycolytic enzymes

1985 • 137 citations

Studies on mammary gland involution

1968 • 136 citations

Characterization and Cloning of the mRNAs Specific for the Lactating Mouse Mammary Gland

1982 • 134 citations

The molecular basis of retinoic acid action. Transcriptional regulation of tissue transglutaminase gene expression in macrophages.

1988 • 128 citations

Epithelium-dependent extracellular matrix synthesis in transforming growth factor-beta 1-growth-inhibited mouse mammary gland.

1990 • 124 citations

Regulation of the synthesis and activity of urokinase plasminogen activator in A549 human lung carcinoma cells by transforming growth factor-beta

1988 • 118 citations

Molecular cloning and analysis of DNA complementary to three mouse Mr = 68,000 heat shock protein mRNAs.

1986 • 116 citations

Removal of basement membrane in the involuting breast.

1976 • 96 citations

Regulation of transglutaminase type II by transforming growth factor-beta 1 in normal and transformed human epidermal keratinocytes.

1990 • 95 citations

The development of rat palatal shelves in vitro

1975 • 94 citations

Studies on mammary gland involution

1968 • 90 citations

Gene expression during the early phases of regression of the androgen-dependent Shionogi mouse mammary carcinoma.

1988 • 88 citations

Characterization and expression of a murine gene homologous to human EPA/TIMP: a virus-induced gene in the mouse.

1987 • 79 citations

Characterization of the Products of a Gene Expressed During Androgen-Programmed Cell Death and their Potential use as a Marker of Urogenital Injury

1990 • 73 citations

The Cell and Tissue Biology

2014 • 71 citations

Increased activity of plasminogen activators during involution of the rat ventral prostate

1984 • 63 citations

Brain tubutin and actin cDNA sequence: isolation of recombinant plasmids

1980 • 57 citations

Immunolocalization of Clusterin in the Ram Testis, Rete Testis, and Excurrent Ducts1

1985 • 50 citations

Induction of the endogenous whey acidic protein (Wap) gene and a Wap-myc hybrid gene in primary murine mammary organoids

1990 • 40 citations

Harvey-ras mediated neoplastic development in the mouse mammary gland.

1989 • 31 citations

Effects of Administration of Oxytocin and Prolactin on Nucleic Acids and Phosphoprotein Contents of Mammary Glands in Lactating Rats

1962 • 11 citations