Oncogenes, growth factors, receptor expression and proliferation markers in digestive neuroendocrine tumours. A critical reappraisal

Histological Typing of Endocrine Tumours

2000 • 741 citations

Molecular pharmacology of somatostatin receptor subtypes

1997 • 411 citations

Vasoactive intestinal peptide regulates mitosis, differentiation and survival of cultured sympathetic neuroblasts

1990 • 317 citations

Expression of vascular endothelial growth factor in digestive neuroendocrine tumours

1998 • 271 citations

Treatment of Neuroendocrine GEP Tumours with Somatostatin Analogues

2000 • 160 citations

Characterization of the antiproliferative signal mediated by the somatostatin receptor subtype sst5

1997 • 137 citations

Mutation of the MENIN gene in sporadic pancreatic endocrine tumors.

1998 • 136 citations

Mutations of the DPC4/Smad4 gene in neuroendocrine pancreatic tumors

1999 • 135 citations

Somatostatin Activation of Mitogen-Activated Protein Kinase via Somatostatin Receptor 1 (SSTR1)

1999 • 134 citations

Genetic alterations in gastrinomas and nonfunctioning pancreatic neuroendocrine tumors: an analysis of p16/MTS1 tumor suppressor gene inactivation.

1998 • 129 citations

Alterations in the p16^INK4a/CDKN2A Tumor Suppressor Gene in Gastrinomas

2000 • 127 citations

Induction of wild-type p53, Bax, and acidic endonuclease during somatostatin-signaled apoptosis in MCF-7 human breast cancer cells

1998 • 123 citations

Growth factor receptor expression in human gastroenteropancreatic neuroendocrine tumours

1998 • 118 citations

sst2 Somatostatin Receptor Mediates Negative Regulation of Insulin Receptor Signaling through the Tyrosine Phosphatase SHP-1

1998 • 113 citations

Role of disease‐causing genes in sporadic pancreatic endocrine tumors: MEN1 andVHL

2001 • 105 citations

Genotype/Phenotype Correlation of Multiple Endocrine Neoplasia Type 1 Gene Mutations in Sporadic Gastrinomas

2000 • 102 citations

Pancreatic endocrine tumours: evidence for a tumour suppressor pathogenesis and for a tumour suppressor gene on chromosome 17p

1998 • 85 citations

Somatostatin Receptors

2000 • 82 citations

p27: A potential main inhibitor of cell proliferation in digestive endocrine tumors but not a marker of benign behavior

2001 • 70 citations

Overexpression of the tumour suppressor gene p53 is not implicated in neuroendocrine tumour carcinogenesis

1995 • 62 citations

Expression of Growth Factors and Their Receptors in Neuroendocrine Gut and Pancreatic Tumors, and Prognostic Factors for Survival

1994 • 57 citations

Antitumor Effect of a Neutralizing Antibody to Vascular Endothelial Growth Factor on Liver Metastasis of Endocrine Neoplasm

1998 • 48 citations

p53 tumour suppressor gene expression in pancreatic neuroendocrine tumour cells.

1996 • 40 citations

Mack Forster Award Lecture Receptor nuclear medicine: vasointestinal peptide and somatostatin receptor scintigraphy for diagnosis and treatment of tumour patients

1997 • 37 citations

Somatostatin receptor subtype 3 mediates the inhibitory action of somatostatin on gastric smooth muscle cells

1995 • 28 citations

Long-term octreotide treatment of metastatic carcinoid tumor

2000 • 19 citations

Analysis of K-ras gene mutations in rare pancreatic and ampullary tumours

1998 • 14 citations

Advances in Pancreatic Disease, Molecular Biology, Diagnosis and Treatment

1997 • 12 citations

Inhibition of L-Type Calcium Channels by Octreotide in Isolated Human Neuroendocrine Tumor Cells of the Gut

1998 • 11 citations