p53 tumour suppressor gene expression in pancreatic neuroendocrine tumour cells.

p53 Mutations in Human Cancers

1991 • 8,133 citations

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

1984 • 4,180 citations

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

Mutational hot spot in the p53 gene in human hepatocellular carcinomas

1991 • 1,525 citations

Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

1991 • 1,418 citations

Growth of human hepatoma cells lines with differentiated functions in chemically defined medium.

1982 • 1,367 citations

Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line

1979 • 1,305 citations

Increased expression of mutant forms of p53 oncogene in primary lung cancer

1990 • 1,045 citations

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

1992 • 871 citations

Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line.

1991 • 712 citations

Absence of HeLa Cell Contamination in 169 Cell Lines Derived From Human Tumors2

1977 • 648 citations

Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation

1991 • 617 citations

An immunochemical analysis of the human nuclear phosphoprotein p53

1992 • 533 citations

Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation

1991 • 507 citations

Synaptophysin: a marker protein for neuroendocrine cells and neoplasms.

1986 • 479 citations

Establishment of a continuous tumor‐cell line (PANC‐1) from a human carcinoma of the exocrine pancreas

1975 • 478 citations

Monoclonal antibodies against simian virus 40 T antigens: evidence for distinct sublcasses of large T antigen and for similarities among nonviral T antigens

1980 • 430 citations

Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer

1991 • 375 citations

Analysis of p53 expression in human tumours: an antibody raised against human p53 expressed in Escherichia coli

1992 • 335 citations

Hepatitis B surface antigen produced by a human hepatoma cell line

1976 • 323 citations

Exocrine pancreatic tumours and their histological classification. A study based on 167 autopsy and 97 surgical cases

1983 • 277 citations

p53 point mutation in HPV negative human cervical carcinoma cell lines.

1991 • 271 citations

p53 transformation-related protein: Detection by monoclonal antibody in mouse and human cells

1981 • 222 citations

Establishment and characterization of a human carcinoid in nude mice and effect of various agents on tumor growth

1991 • 222 citations

The Exocrine Pancreas: Biology, Pathobiology, and Diseases.

1986 • 218 citations

Interactions between human tumor cells and fibroblasts stimulate hyaluronate synthesis.

1984 • 203 citations

p53 and K-RAS alterations in pancreatic epithelial cell lesions.

1993 • 186 citations

Pancreatic acinar cell carcinoma. An analysis of cell lineage markers, p53 expression, and Ki-ras mutation.

1993 • 184 citations

Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex

1986 • 175 citations

Human pancreatic carcinomas and cell lines reveal frequent and multiple alterations in the p53 and Rb-1 tumor-suppressor genes.

1992 • 171 citations

The p53 tumor suppressor protein, a modulator of cell proliferation.

1992 • 171 citations

Sequence-specific DNA purification by triplex affinity capture.

1992 • 131 citations

Multipotential phenotypic expression of genes encoding peptide hormones in rat insulinoma cell lines.

1987 • 124 citations

Tumour suppressor gene products, proliferation, and differentiation markers in lung neuroendocrine neoplasms

1992 • 114 citations

Isolation of glucagon-secreting cell lines by cloning insulinoma cells

1986 • 112 citations

Role of p53 mutations in endocrine tumorigenesis: mutation detection by polymerase chain reaction-single strand conformation polymorphism.

1992 • 110 citations

Establishment of a carcinoembryonic antigen-producing cell line from human pancreatic carcinoma.

1980 • 101 citations

A Study of Biological Behavior Based on the Expression of a Proliferating Antigen in Neuroendocrine Tumors of the Digestive System

1992 • 66 citations

Molecular biology of cancer genes

1991 • 34 citations

Molecular cloning, expression and in vitro functional characterization of Myb-related proteins in Xenopus

1992 • 23 citations

[Endocrine tumors of the pancreas and duodenum].

1987 • 6 citations