Overexpression of the tumour suppressor gene p53 is not implicated in neuroendocrine tumour carcinogenesis

p53 Mutations in Human Cancers

1991 • 8,133 citations

Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms

1990 • 3,720 citations

STUDIES ON ANTIBODY PRODUCTION

1955 • 1,573 citations

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

1989 • 1,214 citations

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

1988 • 1,140 citations

Increased expression of mutant forms of p53 oncogene in primary lung cancer

1990 • 1,045 citations

p53: oncogene or anti-oncogene?

1990 • 812 citations

TP53 tumor suppressor gene: A model for investigating human mutagenesis

1992 • 584 citations

An immunochemical analysis of the human nuclear phosphoprotein p53

1992 • 533 citations

An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms

1994 • 513 citations

Widespread p53 overexpression in human malignant tumors. An immunohistochemical study using methacarn-fixed, embedded tissue.

1992 • 257 citations

p53: the ultimate tumor suppressor gene?

1992 • 209 citations

High frequency of somatically acquired p53 mutations in small-cell lung cancer cell lines and tumors

1993 • 207 citations

Mutant p53 proteins bind hsp 72/73 cellular heat shock-related proteins in SV40-transformed monkey cells.

1987 • 162 citations

Problems with p53 immunohistochemical staining: the effect of fixation and variation in the methods of evaluation

1994 • 152 citations

Tumour suppressor gene products, proliferation, and differentiation markers in lung neuroendocrine neoplasms

1992 • 114 citations

Variations in immunohistochemical detection of p53 protein overexpression in cervical carcinomas with different antibodies and methods of detection

1994 • 106 citations

Transformation associated p53 protein is encoded by a gene on human chromosome 17

1985 • 77 citations

Infrequent mutations of the p53 gene in pulmonary carcinoid tumors.

1993 • 65 citations

The Frequency of Gastrointestinal Endocrine Tumours in a Well-defined Population – Northern Ireland 1970–1985

1989 • 65 citations

Retinoblastoma and p53 tumour suppressor gene protein expression in carcinomas of the thyroid gland

1994 • 62 citations

Mutational spectrum of the p53 gene in human small-cell lung cancer and relationship to clinicopathological data

1994 • 55 citations

Inactivation of the p53 Gene Is not Required for Tumorigenesis of Medullary Thyroid Carcinoma or Pheochromocytoma

1992 • 30 citations

Neuroendocrine cells within colorectal tumours induced by dimethylhydrazine

1986 • 19 citations