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Pseudorabies Virus Replication and Assembly in the Rodent Central Nervous System

Data up to Jan 2025

Published1995
Citations26
References112

Total Citations Per Year

Abstract

References (112)

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

Classification and Nomenclature of Viruses

1987 • 1,331 citations

Experimental Therapy of Human Glioma by Means of a Genetically Engineered Virus Mutant

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Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway

1990 • 972 citations

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Cellular immune reactivity within the CNS

1986 • 771 citations

The central organization of the vagus nerve innervating the stomach of the rat

1985 • 490 citations

CNS cell groups regulating the sympathetic outflow to adrenal gland as revealed by transneuronal cell body labelling with pseudorabies virus

1989 • 484 citations

The Golgi complex: In vitro veritas?

1992 • 481 citations

Polarized sorting of viral glycoproteins to the axon and dendrites of hippocampal neurons in culture

1990 • 425 citations

Entry of alphaherpesviruses into cells

1993 • 375 citations

Neurotropic properties of pseudorabies virus: uptake and transneuronal passage in the rat central nervous system

1990 • 337 citations

Pseudorabies virus infection of the rat central nervous system: ultrastructural characterization of viral replication, transport, and pathogenesis

1993 • 327 citations

Glycoproteins Specified by Herpes Simplex Viruses

1985 • 314 citations

O-linked oligosaccharides are acquired by herpes simplex virus glycoproteins in the Golgi apparatus

1983 • 279 citations

Ultrastructural demonstration of a gastric monosynaptic vagal circuit in the nucleus of the solitary tract in rat

1989 • 263 citations

Monensin inhibits the processing of herpes simplex virus glycoproteins, their transport to the cell surface, and the egress of virions from infected cells

1982 • 257 citations

Viruses as transneuronal tracers

1990 • 236 citations

Direction of transneuronal transport of herpes simplex virus 1 in the primate motor system is strain-dependent.

1991 • 221 citations

Pseudorabies virus envelope glycoprotein gI influences both neurotropism and virulence during infection of the rat visual system

1992 • 212 citations

Two α-herpesvirus strains are transported differentially in the rodent visual system

1991 • 208 citations

Entry of herpes simplex virus 1 in BJ cells that constitutively express viral glycoprotein D is by endocytosis and results in degradation of the virus

1988 • 204 citations

An efficient deletion mutant packaging system for defective herpes simplex virus vectors: potential applications to human gene therapy and neuronal physiology.

1990 • 203 citations

Expression of nerve growth factor in vivo from a defective herpes simplex virus 1 vector prevents effects of axotomy on sympathetic ganglia.

1992 • 203 citations

Pseudorabies virus glycoproteins gII and gp50 are essential for virus penetration

1991 • 203 citations

Herpesvirus Diseases of Cattle, Horses, and Pigs

1989 • 197 citations

Retrograde transneuronal transfer of Herpes simplex virus type 1 (HSV 1) from motoneurones

1987 • 195 citations

Structure and assembly of herpesviruses

1993 • 193 citations

Spatiotemporal responses of astrocytes, ramified microglia, and brain macrophages to central neuronal infection with pseudorabies virus

1993 • 191 citations

Spread of herpes simplex virus in peripheral nerves

1971 • 186 citations

Pseudorabies virus envelope glycoproteins gp50 and gII are essential for virus penetration, but only gII is involved in membrane fusion

1992 • 183 citations

Effect of brefeldin A on alphaherpesvirus membrane protein glycosylation and virus egress

1991 • 183 citations

Transneuronal Transfer of Herpes Virus from Peripheral Nerves to Cortex and Brainstem

1989 • 175 citations

Herpes-Type Virus of the Frog Renal Adenocarcinoma

1969 • 173 citations

Gene therapy of maliganant brain tumors: A rat glioma line bearing the herpes simplex virus type 1‐thymidine kinase gene and wild type retrovirus kills other tumor cells

1992 • 170 citations

Innervation of the Heart and Its Central Medullary Origin Defined by Viral Tracing

1994 • 169 citations

Contribution of single genes within the unique short region of Aujeszky's disease virus (suid herpesvirus type 1) to virulence, pathogenesis and immunogenicity

1992 • 161 citations

Specific pseudorabies virus infection of the rat visual system requires both gI and gp63 glycoproteins

1993 • 159 citations

Herpes simplex virus infection of the human sensory neuron

1988 • 145 citations

Pathways of viral gene expression during acute neuronal infection with HSV-1

1992 • 142 citations

Molecular Biology of Pseudorabies Virus

1985 • 141 citations

Uptake and Transport of Herpes Simplex Virus in Neurites of Rat Dorsal Root Ganglia Cells in Culture

1984 • 140 citations

Neuron to neuron transmission of herpes simplex virus

1982 • 136 citations

VIRUSES AND THE VERSATILE MACROPHAGE

1985 • 136 citations

Neuronal and transneuronal tracing in the trigeminal system of the rat using the herpes virus suis

1983 • 134 citations

Aujeszky’s Disease (Pseudorabies) in Pigs

1989 • 129 citations

Neural spread of herpes simplex virus types 1 and 2 in mice after corneal or subcutaneous (footpad) inoculation

1978 • 127 citations

Two neurotropic viruses, herpes simplex virus type 1 and mouse hepatitis virus, spread along different neural pathways from the main olfactory bulb

1993 • 126 citations

The Phospholipid Composition of Extracellular Herpes Simplex Virions Differs from That of Host Cell Nuclei

1994 • 122 citations

An investigation into the early stages of the inflammatory response following ibotenic acid-induced neuronal degeneration

1990 • 115 citations

Study on the propagation of Herpes simplex virus (type 2) into the brain after intraocular injection

1974 • 111 citations

Molecular biology of pseudorabies (Aujeszky's disease) virus

1991 • 102 citations

Expression of a functional foreign gene in adult mammalian brain following in Vivo transfer via a herpes simplex virus type 1 defective viral vector

1991 • 101 citations

Differences in attachment between herpes simplex type 1 and type 2 viruses to neurons and glial cells

1980 • 97 citations

Neurovirulence of pseudorabies virus.

1995 • 96 citations

Glycoprotein D of herpes simplex virus encodes a domain which precludes penetration of cells expressing the glycoprotein by superinfecting herpes simplex virus

1990 • 90 citations

Intraaxonal transport of Herpes simplex virus in the rat central nervous system

1977 • 86 citations

Role of cytoplasmic vacuoles in varicella-zoster virus glycoprotein trafficking and virion envelopment

1988 • 86 citations

Attachment of Herpes Simplex Virus to Neurons and Glial Cells

1978 • 86 citations

Morphological studies of the neural spread of herpes simplex virus to the central nervous system

1970 • 85 citations

Role of pseudorabies virus glycoprotein gI in virus release from infected cells

1987 • 84 citations

Envelope glycoprotein gp50 of pseudorabies virus is essential for virus entry but is not required for viral spread in mice

1993 • 82 citations

Golgi-like, transneuronal retrograde labelling with CNS injections of herpes simplex virus type

1989 • 80 citations

The Pathogenesis of Pseudorabies in Mice following Peripheral Inoculation

1974 • 79 citations

Abortive and productive infections of human mononuclear phagocytes by type I herpes simplex virus.

1978 • 79 citations

Herpes simplex virus type I infection of the CNS induces major histocompatibility complex antigen expression on rat microglia

1990 • 79 citations

Glycoprotein H of pseudorabies virus is essential for entry and cell-to-cell spread of the virus

1992 • 77 citations

Transneuronal transport of herpes simplex virus from the cervical vagus to brain neurons with axonal inputs to central vagal sensory nuclei in the rat

1991 • 74 citations

Effects of gene transfer into cultured CNS neurons with a replication-defective herpes simplex virus type 1 vector

1992 • 72 citations

Infection of the mammalian nervous system by pseudorabies virus (PRV)

1994 • 70 citations

Role of essential glycoproteins gII and gp50 in transneuronal transfer of pseudorabies virus from the hypoglossal nerves of mice

1993 • 70 citations

Projections from rabbit caudal medulla to C1 and A5 sympathetic premotor neurons, demonstrated with phaseolus leucoagglutinin and herpes simplex virus

1992 • 66 citations

Transneuronal transfer of herpes simplex virus type 1 (HSV 1) from mixed limb nerves to the CNS. I. Sequence of transfer from sensory, motor, and sympathetic nerve fibres to the spinal cord

1992 • 65 citations

β-galactosidase expressing recombinant pseudorabies virus for light and electron microscopic study of transneuronally labeled CNS neurons

1991 • 64 citations

Complementation analysis of pseudorabies virus gE and gI mutants in retinal ganglion cell neurotropism

1994 • 64 citations

The gene encoding the gIII envelope protein of pseudorabies virus vaccine strain Bartha contains a mutation affecting protein localization

1989 • 62 citations

Genetics of Natural Resistance to Herpes Simplex Virus Type 1 Latent Infection of the Peripheral Nervous System in Mice

1986 • 61 citations

Immunohistochemical identification of trigeminal ganglion neurons that innervate the mouse cornea: Relevance to intercellular spread of herpes simplex virus

1993 • 57 citations

Herpes simplex virus glycoprotein D is sufficient to induce spontaneous pH-independent fusion in a cell line that constitutively expresses the glycoprotein

1988 • 54 citations

Binding, uptake and retrograde axonal transport of herpes virus suis in sympathetic neurons

1986 • 53 citations

Glycoprotein gp50-negative pseudorabies virus: a novel approach toward a nonspreading live herpesvirus vaccine

1993 • 51 citations

Selective spread of herpes simplex virus in the central nervous system after ocular inoculation

1989 • 51 citations

Multifocal CNS demyelination following peripheral inoculation with herpes simplex virus type 1

1987 • 50 citations

Trans‐Golgi reticulum

1991 • 47 citations

Release of pseudorabies virus from infected cells is controlled by several viral functions and is modulated by cellular components

1989 • 46 citations

Interactions of Pseudorabies virus with swine alveolar macrophages I: virus replication

1989 • 41 citations

Ultrastructure and function in sympathetic ganglia isolated from rats infected with pseudorabies virus

1978 • 40 citations

Intrinsic resistance to viral infection. Mouse macrophage restriction of herpes simplex virus replication.

1988 • 39 citations

Comparative pathogenesis of three strains of pseudorabies virus in pigs

1989 • 39 citations

A neurobiological approach to neurotropic viruses

1980 • 37 citations

Retrograde transneuronal transport of Herpex simplex virus in the retina after injection in the superior colliculus, hypothalamus and optic chiasm

1989 • 36 citations

Firefly Luciferase as a Marker for Herpesvirus (pseudorabies virus) Replication in Vitro and in Vivo

1991 • 30 citations

Herpes simplex virus-based vectors

1995 • 29 citations

Zur primären Schädigung vegetativer Ganglien nach Infektion mit demHerpes suis Virus bei verschiedenen Tierarten

1967 • 28 citations

Transformation of Golgi membrane into the envelope of herpes simplex virus in rat anterior pituitary cells.

1989 • 27 citations

Anterograde transport of HSV-1 and HSV-2 in the visual system

1992 • 26 citations

Polarized distribution of the viral glycoproteins of vesicular stomatitis, fowl plague and Semliki Forest viruses in hippocampal neurons in culture: a light and electron microscopic study

1993 • 24 citations

Gene transfer into the nervous system

1987 • 24 citations

Spread of herpes simplex virus type 1 in the central nervous system during experimentally reactivated encephalitis

1990 • 24 citations

Inhibition by Brefeldin A of the envelopment of nucleocapsids in herpes simplex virus type 1-infected Vero cells

1994 • 23 citations

Involvement of Golgi apparatus and a restructured nuclear envelope during biogenesis and transport of herpes simplex virus glycoproteins.

1985 • 23 citations

Innate resistance to herpes simplex virus infection. Human lymphocyte and monocyte inhibition of viral replication.

1990 • 22 citations

Identifying HSV infected neurons after ocular inoculation

1987 • 22 citations

Infiltration of carbon-labelled monocytes into the dorsal motor nucleus following an intraneural injection of ricinus communis agglutinin-60 into the vagus nerve in rats.

1988 • 21 citations

Intramembrane changes occurring during maturation of herpes simplex virus type 1: freeze-fracture study

1978 • 18 citations

Variation in resistance to herpes simplex virus type 1 of oligodendrocytes derived from inbred strains of mice

1991 • 18 citations

Electron microscopic observations on FL cells infected with herpes simplex virus. II. Envelopment.

1971 • 15 citations

Pseudorabies virus infections in explants of porcine nasal mucosa

1991 • 15 citations

Morphogenesis of Three Pseudorabies Virus Strains in Porcine Nasal Mucosa

1991 • 13 citations

A gene delivery/recall system for neurons which utilizes ribonucleotide reductase-negative herpes simplex viruses

1991 • 11 citations

A quantitative assay of retrograde transported HSV in the trigeminal ganglion.

1992 • 8 citations

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