Sequential action of mitochondrial chaperones in protein import into the matrix.

Speculations on the functions of the major heat shock and glucose-regulated proteins

1986 • 1,574 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria.

1982 • 1,152 citations

Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria

1989 • 933 citations

Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells

1989 • 884 citations

Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins

1990 • 756 citations

Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis

1989 • 676 citations

Protein Sorting to Mitochondria: Evolutionary Conservations of Folding and Assembly

1990 • 494 citations

Loss of BiP/GRP78 function blocks translocation of secretory proteins in yeast.

1990 • 435 citations

70-kD heat shock-related protein is one of at least two distinct cytosolic factors stimulating protein import into mitochondria.

1988 • 380 citations

Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle.

1986 • 337 citations

[13] Immunochemical identification of membrane proteins after sodium dodecyl sulfate—polyacrylamide gel electrophoresis

1983 • 309 citations

Mitochondrial proteins essential for viability mediate protein import into yeast mitochondria

1991 • 278 citations

A 42K outer-membrane protein is a component of the yeast mitochondrial protein import site

1989 • 274 citations

A novel in vitro transcription-translation system: accurate and efficient synthesis of single proteins from cloned DNA sequences.

1984 • 251 citations

A Highly Evolutionarily Conserved Mitochondrial Protein Is Structurally Related to the Protein Encoded by the Escherichia coli groEL Gene

1988 • 247 citations

How do polypeptides cross the mitochondrial membranes?

1990 • 246 citations

A precursor protein partly translocated into yeast mitochondria is bound to a 70 kd mitochondrial stress protein.

1990 • 242 citations

SSC1, an Essential Member of the Yeast HSP70 Multigene Family, Encodes a Mitochondrial Protein

1989 • 242 citations

The amino-terminal region of an imported mitochondrial precursor polypeptide can direct cytoplasmic dihydrofolate reductase into the mitochondrial matrix.

1984 • 236 citations

Import of proteins into yeast mitochondria: the purified matrix processing protease contains two subunits which are encoded by the nuclear MAS1 and MAS2 genes.

1988 • 219 citations

The mitochondrial chaperonin hsp60 is required for its own assembly

1990 • 205 citations

SSC1, a member of the 70-kDa heat shock protein multigene family of Saccharomyces cerevisiae, is essential for growth.

1987 • 205 citations

A 70-kd protein of the yeast mitochondrial outer membrane is targeted and anchored via its extreme amino terminus.

1984 • 198 citations

Import of proteins into yeast mitochondria: the nuclear MAS2 gene encodes a component of the processing protease that is homologous to the MAS1-encoded subunit.

1988 • 149 citations

Identification of a groES-like chaperonin in mitochondria that facilitates protein folding.

1990 • 135 citations

Mitochondrial protein import: involvement of the mature part of a cleavable precursor protein in the binding to receptor sites.

1987 • 134 citations

(Mg–ATP)-dependent self-assembly of molecular chaperone GroEL

1990 • 131 citations

A homologue of the bacterial heat-shock gene DnaJ that alters protein sorting in yeast

1991 • 117 citations

Precursor proteins in transit through mitochondrial contact sites interact with hsp70 in the matrix

1990 • 98 citations

Molecular cloning of mtp70, a mitochondrial member of the hsp70 family.

1989 • 97 citations

A rapid method for the isolation of peroxisomes from rat liver

1986 • 94 citations

A Normal Mitochondrial Protein is Selectively Synthesized and Accumulated During Heat Shock in Tetrahymena Thermophila

1987 • 88 citations

Translocation of proteins across the mitochondrial inner membrane, but not into the outer membrane, requires nucleoside triphosphates in the matrix.

1989 • 87 citations

Mitochondria can import artificial precursor proteins containing a branched polypeptide chain or a carboxy-terminal stilbene disulfonate.

1988 • 76 citations

A member of the Hsp70 family is localized in mitochondria and resembles Escherichia coli DnaK.

1989 • 71 citations

Energy requirements for unfolding and membrane translocation of precursor proteins during import into mitochondria.

1990 • 67 citations

Function of the maize mitochondrial chaperonin hsp60: specific association between hsp60 and newly synthesized F1-ATPase alpha subunits.

1990 • 58 citations

Molecular Cloning of mtp70, a Mitochondrial Member of the hsp70 Family

1989 • 26 citations

Identification of a 66 KDa protein associated with yeast mitochondrial ATP synthase as heat shock protein hsp60

1990 • 25 citations

Function of the Maize Mitochondrial Chaperonin hsp60: Specific Association between hsp60 and Newly Synthesized F1-ATPase Alpha Subunits

1990 • 16 citations

[29] Preparation and use of antibodies against insoluble membrane proteins

1983 • 11 citations