Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Methods of Enzymatic Analysis

1975 • 20,446 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

Methods of enzymatic analysis

1985 • 3,497 citations

A rapid, sensitive method for detection of alkaline phosphatase-conjugated anti-antibody on Western blots

1984 • 2,189 citations

Speculations on the functions of the major heat shock and glucose-regulated proteins

1986 • 1,574 citations

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

1984 • 1,533 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

An hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

1986 • 1,457 citations

Biogenesis of Mitochondria

1988 • 1,396 citations

Homologous plant and bacterial proteins chaperone oligomeric protein assembly

1988 • 1,316 citations

70K heat shock related proteins stimulate protein translocation into microsomes

1988 • 1,276 citations

Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria

1989 • 933 citations

Proteins as molecular chaperones

1987 • 910 citations

Mitochondrial protein import

1989 • 820 citations

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria

1986 • 723 citations

GroE heat-shock proteins promote assembly of foreign prokaryotic ribulose bisphosphate carboxylase oligomers in Escherichia coli

1989 • 703 citations

Uncoating ATPase is a member of the 70 kilodalton family of stress proteins

1986 • 607 citations

Primary structure of a human mitochondrial protein homologous to the bacterial and plant chaperonins and to the 65-kilodalton mycobacterial antigen.

1989 • 492 citations

Transport of proteins into mitochondria: Translocational intermediates spanning contact sites between outer and inner membranes

1985 • 470 citations

Purification and properties of groE, a host protein involved in bacteriophage assembly

1979 • 426 citations

Transient association of newly synthesized unfolded proteins with the heat-shock GroEL protein

1988 • 388 citations

Mitochondrial protein import: Identification of processing peptidase and of PEP, a processing enhancing protein

1988 • 388 citations

70-kD heat shock-related protein is one of at least two distinct cytosolic factors stimulating protein import into mitochondria.

1988 • 380 citations

Purification and properties of the groES morphogenetic protein of Escherichia coli.

1986 • 364 citations

Transport into mitochondria and intramitochondrial sorting of the Fe/S protein of ubiquinol-cytochrome c reductase

1986 • 340 citations

Characterization of the yeast HSP60 gene coding for a mitochondrial assembly factor

1989 • 335 citations

Mitochondrial protein import: Nucleoside triphosphates are involved in conferring import-competence to precursors

1987 • 322 citations

Coming in from the cold

1988 • 285 citations

Successive translocation into and out of the mitochondrial matrix: Targeting of proteins to the intermembrane space by a bipartite signal peptide

1987 • 275 citations

A Highly Evolutionarily Conserved Mitochondrial Protein Is Structurally Related to the Protein Encoded by the Escherichia coli groEL Gene

1988 • 247 citations

Characterization of translocation contact sites involved in the import of mitochondrial proteins.

1987 • 219 citations

Heavy-chain binding protein recognizes aberrant polypeptides translocated in vitro

1988 • 219 citations

SSC1, a member of the 70-kDa heat shock protein multigene family of Saccharomyces cerevisiae, is essential for growth.

1987 • 205 citations

The imported preprotein of the proteolipid subunit of the mitochondrial ATP synthase from Neurospora crassa. Molecular cloning and sequencing of the mRNA.

1982 • 205 citations

Protein unfolding and the energetics of protein translocation across biological membranes

1988 • 192 citations

Seventy-kilodalton heat shock proteins and an additional component from reticulocyte lysate stimulate import of M13 procoat protein into microsomes.

1988 • 187 citations

Unfolding and refolding of a purified precursor protein during import into isolated mitochondria.

1988 • 182 citations

MAS1, a gene essential for yeast mitochondrial assembly, encodes a subunit of the mitochondrial processing protease.

1988 • 181 citations

Interaction of heavy chain binding protein (BiP/GRP78) with adenine nucleotides.

1989 • 176 citations

Identification of a second Escherichia coli groE gene whose product is necessary for bacteriophage morphogenesis.

1981 • 165 citations

A highly evolutionarily conserved mitochondrial protein is structurally related to the protein encoded by the Escherichia coli groEL gene.

1988 • 163 citations

Processing peptidase of Neurospora mitochondria. Two-step cleavage of imported ATPase subunit 9

1984 • 157 citations

The processing peptidase of yeast mitochondria: the two co-operating components MPP and PEP are structurally related.

1988 • 152 citations

A chimeric mitochondrial precursor protein with internal disulfide bridges blocks import of authentic precursors into mitochondria and allows quantitation of import sites.

1988 • 143 citations

Cell biology: An unfolding story of protein translocation

1986 • 126 citations

Dissociation of the ribulosebisphosphate-carboxylase large-subunit binding protein into dissimilar subunits

1987 • 111 citations

Identification and electron microscopic analysis of a chaperonin oligomer from Neurospora crassa mitochondria.

1989 • 81 citations

The Rubisco subunit binding protein

1988 • 71 citations

Amino-Acid Sequence Homology of a Polymorphic Cellular Protein from Human Lymphocytes and the Chaperonins fromEscherichia coli (groEL)and Chloroplasts (Rubisco-Binding Protein)

1988 • 34 citations