Phagocytic and macropinocytic activity in MARCKS-deficient macrophages and fibroblasts

Cytochemical Identification of Monocytes and Granulocytes

1971 • 2,735 citations

MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium–calmodulin

1992 • 728 citations

Brief Report: Simplified Myeloperoxidase Stain Using Benzidine Dihydrochloride

1965 • 673 citations

SIMPLIFIED MYELOPEROXIDASE STAIN USING BENZIDINE DIHYDROCHLORIDE.

1965 • 540 citations

The MARCKS family of cellular protein kinase C substrates.

1993 • 484 citations

The Marcks brothers: A family of protein kinase C substrates

1992 • 474 citations

Tumor-promoting phorbol esters stimulate C3b and C3b' receptor-mediated phagocytosis in cultured human monocytes.

1982 • 444 citations

Phagocytosis by zippers and triggers

1995 • 314 citations

A role for MARCKS, the alpha isozyme of protein kinase C and myosin I in zymosan phagocytosis by macrophages.

1995 • 303 citations

MARCKS deficiency in mice leads to abnormal brain development and perinatal death.

1995 • 291 citations

Effects of cytochalasin B on polymorphonuclear leucocyte locomotion, phagocytosis and glycolysis

1972 • 258 citations

Tyrosine phosphorylation of the gamma subunit of Fc gamma receptors, p72syk, and paxillin during Fc receptor-mediated phagocytosis in macrophages.

1994 • 244 citations

Macrophage colony-stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages.

1989 • 242 citations

Phosphorylation-regulated calmodulin binding to a prominent cellular substrate for protein kinase C

1989 • 241 citations

Phorbol esters stimulate macropinocytosis and solute flow through macrophages

1989 • 240 citations

Stimulus-dependent myristoylation of a major substrate for protein kinase C

1988 • 216 citations

Tyrosine phosphorylation is required for Fc receptor-mediated phagocytosis in mouse macrophages.

1993 • 201 citations

Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctate structures in macrophage filopodia.

1990 • 195 citations

Phosphorylation, high ionic strength, and calmodulin reverse the binding of MARCKS to phospholipid vesicles.

1994 • 182 citations

Bone marrow-derived macrophages: development and regulation of differentiation markers by colony-stimulating factor and interferons.

1985 • 182 citations

Ca(2+)-independent F-actin assembly and disassembly during Fc receptor-mediated phagocytosis in mouse macrophages.

1991 • 175 citations

MARCKS regulates membrane ruffling and cell spreading

1997 • 161 citations

Phosphorylation reverses the membrane association of peptides that correspond to the basic domains of MARCKS and neuromodulin

1994 • 152 citations

Biologic and Biochemical Activities of Continuous Macrophage Cell Lines P388D1 and J774.1

1977 • 143 citations

Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/macrophage progenitors may be responsible for TNFalpha overproduction.

1997 • 140 citations

Phosphorylation-dependent binding of a synthetic MARCKS peptide to calmodulin.

1991 • 126 citations

Immunoglobulin-mediated phagocytosis by human monocytes requires protein kinase C activation. Evidence for protein kinase C translocation to phagosomes.

1992 • 123 citations

Differential requirements for cellular cytoskeleton in human macrophage complement receptor- and Fc receptor-mediated phagocytosis.

1991 • 113 citations

Development, Differentiation, and Maturation of Macrophages in the Fetal Mouse Liver

1990 • 105 citations

Phorbol myristate acetate stimulates pinocytosis and membrane spreading in mouse peritoneal macrophages.

1980 • 103 citations

Membrane Association of the Myristoylated Alanine-rich C Kinase Substrate (MARCKS) Protein.

1995 • 102 citations

Tumor necrosis factor alpha modifies agonist-dependent responses in human neutrophils by inducing the synthesis and myristoylation of a specific protein kinase C substrate.

1990 • 95 citations

Disruption of the MacMARCKS gene prevents cranial neural tube closure and results in anencephaly.

1996 • 94 citations

Neural tube defects and abnormal brain development in F52-deficient mice.

1996 • 94 citations

Protein kinase C-mediated phosphorylation and calmodulin binding of recombinant myristoylated alanine-rich C kinase substrate (MARCKS) and MARCKS-related protein.

1994 • 91 citations

Phagocytosis of Unopsonized Zymosan by Human Monocyte-Derived Macrophages: Maturation and Inhibition by Mannan

1985 • 89 citations

The human myristoylated alanine-rich C kinase substrate (MARCKS) gene (MACS). Analysis of its gene product, promoter, and chromosomal localization

1991 • 85 citations

MacMARCKS Mutation Blocks Macrophage Phagocytosis of Zymosan

1995 • 75 citations

Myristoylation-dependent and Electrostatic Interactions Exert Independent Effects on the Membrane Association of the Myristoylated Alanine-rich Protein Kinase C Substrate Protein in Intact Cells

1996 • 68 citations

Cell surface dynamics of neutrophils stimulated with phorbol esters or retinoids.

1987 • 66 citations

Comparison of Bone Marrow Progenitors Responsive to Granulocyte-Macrophage Colony Stimulating Factor and Macrophage Colony Stimulating Factor-1

1988 • 61 citations

Widespread Neuronal Ectopia Associated with Secondary Defects in Cerebrocortical Chondroitin Sulfate Proteoglycans and Basal Lamina in MARCKS-Deficient Mice

1997 • 57 citations

Diacylglycerols and PMA are particularly effective stimulators of fluid pinocytosis in human neutrophils

1990 • 53 citations

Studies on the molecular mechanisms of human neutrophil Fc receptor-mediated phagocytosis. Evidence that a distinct pathway for activation of the respiratory burst results in reactive oxygen metabolite-dependent amplification of ingestion.

1990 • 51 citations

Role of MacMARCKS in Integrin-dependent Macrophage Spreading and Tyrosine Phosphorylation of Paxillin

1996 • 50 citations

Defective Fc-mediated phagocytosis in C3H/HeJ macrophages. II. Correction by cAMP agonists.

1981 • 48 citations

Regulation of peptide-calmodulin complexes by protein kinase C in vivo.

1993 • 43 citations

Developmental expression of MARCKS and protein kinase C in mice in relation to the exencephaly resulting from MARCKS deficiency

1996 • 41 citations

Reorganization of microfilaments in macrophages after LPS stimulation

1991 • 40 citations

Promoter Sequence, Expression, and Fine Chromosomal Mapping of the Human Gene (MLP) Encoding the MARCKS-like Protein: Identification of Neighboring and Linked Polymorphic Loci forMLPandMACSand Use in the Evaluation of Human Neural Tube Defects

1998 • 39 citations

MacMARCKS Is Not Essential for Phagocytosis in Macrophages

1998 • 36 citations

Enhancement by protein kinase C of prostacyclin receptor-mediated activation of adenylate cyclase through a calmodulin/myristoylated alanine-rich C kinase substrate (MARCKS) system in IC2 mast cells.

1993 • 26 citations

Transgenic Complementation of MARCKS Deficiency with a Nonmyristoylatable, Pseudo-Phosphorylated Form of MARCKS: Evidence for Simultaneous Positive and Dominant-Negative Effects on Central Nervous System Development

1998 • 13 citations

Functional defects of monocyte C3b receptor-mediated phagocytosis in rheumatoid arthritis (RA): evidence for an association with the appearance of a circulating population of non-specific esterase-negative mononuclear phagocytes.

1983 • 10 citations

Increased endocytosis and formation of multivesicular bodies in phorbol ester-stimulated human monoblastic U-937 cells

1989 • 7 citations

The effect of products from bronchoalveolar-derived neutrophils on oxidant production and phagocytic activity of alveolar macrophages.

1988 • 7 citations

Methods for studying immuno-effector functions and antigen presenting activity of human macrophages

1994 • 6 citations

Deleted Work

1955 • 0 citations