Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/macrophage progenitors may be responsible for TNFalpha overproduction.

RAG-1-deficient mice have no mature B and T lymphocytes

1992 • 2,859 citations

A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples.

1993 • 2,807 citations

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis.

1991 • 1,630 citations

Murine Models of Systemic Lupus Erythematosus

1985 • 1,572 citations

Processing of tumour necrosis factor-α precursor by metalloproteinases

1994 • 1,200 citations

A Pathogenetic Role for TNFα in the Syndrome of Cachexia, Arthritis, and Autoimmunity Resulting from Tristetraprolin (TTP) Deficiency

1996 • 742 citations

Regulation of tumour necrosis factor-α processing by a metalloproteinase inhibitor

1994 • 571 citations

Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency

1986 • 558 citations

Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level.

1990 • 495 citations

Prevention of Atherosclerosis in Apolipoprotein E-Deficient Mice by Bone Marrow Transplantation

1995 • 467 citations

Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors.

1989 • 385 citations

Rapid identification of monocytes in a mixed mononuclear cell preparation

1977 • 330 citations

Molecular cloning, characterization, and expression of a cDNA encoding the "80- to 87-kDa" myristoylated alanine-rich C kinase substrate: a major cellular substrate for protein kinase C.

1989 • 318 citations

Rapid insulin-stimulated accumulation of an mRNA encoding a proline-rich protein.

1990 • 247 citations

A growth factor-inducible nuclear protein with a novel cysteine/histidine repetitive sequence.

1990 • 247 citations

Pancreatic islet-specific T-cell clones from nonobese diabetic mice.

1989 • 246 citations

[12] Systems for polyacrylamide gel electrophoresis

1984 • 208 citations

Bone marrow-derived macrophages: development and regulation of differentiation markers by colony-stimulating factor and interferons.

1985 • 182 citations

Generation of biliary lesions after transfer of human lymphocytes into severe combined immunodeficient (SCID) mice.

1989 • 177 citations

Cells expressing human glucocerebrosidase from a retroviral vector repopulate macrophages and central nervous system microglia after murine bone marrow transplantation

1994 • 166 citations

The TIS11 primary response gene is a member of a gene family that encodes proteins with a highly conserved sequence containing an unusual Cys-His repeat.

1991 • 162 citations

The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation.

1995 • 158 citations

Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNF alpha transgenic mice.

1992 • 150 citations

Transfer of human systemic lupus erythematosus in severe combined immunodeficient (SCID) mice.

1990 • 149 citations

Nucleotide sequence of a cDNA encoding TIS11, a message induced in Swiss 3T3 cells by the tumor promoter tetradecanoyl phorbol acetate.

1989 • 135 citations

Phosphorylation of Tristetraprolin, a Potential Zinc Finger Transcription Factor, by Mitogen Stimulation in Intact Cells and by Mitogen-activated Protein Kinase in Vitro

1995 • 129 citations

Molecular cloning and sequence analysis of a mouse Y chromosome RNA transcript expressed in the test is

1987 • 115 citations

Metal binding properties and secondary structure of the zinc-binding domain of Nup475

1996 • 106 citations

Mitogens stimulate the rapid nuclear to cytosolic translocation of tristetraprolin, a potential zinc-finger transcription factor.

1996 • 104 citations

Tumor necrosis factor-alpha and tumor necrosis factor-beta (lymphotoxin) stimulate the production of granulocyte-macrophage colony-stimulating factor, macrophage colony-stimulating factor, and IL-1 in vivo.

1988 • 97 citations

Optimal conditions for proliferation of bone marrow‐derived mouse macrophages in culture: The roles of CSF‐1, serum, Ca²⁺, and adherence

1983 • 94 citations

The human TTP protein: sequence, alignment with related proteins, and chromosomal localization of the mouse and human genes

1991 • 91 citations

Increased circulating CSF-1 (M-CSF) in myeloproliferative disease: association with myeloid metaplasia and peripheral bone marrow extension

1989 • 85 citations

Constitutive activity of the tumor necrosis factor promoter is canceled by the 3' untranslated region in nonmacrophage cell lines; a trans-dominant factor overcomes this suppressive effect.

1992 • 71 citations

Promoter Analysis of Zfp-36 the Mitogen-inducible Gene Encoding the Zinc Finger Protein Tristetraprolin

1995 • 69 citations

A Human Putative Lymphocyte G₀/G₁Switch Gene Homologous to a Rodent Gene Encoding a Zinc-Binding Potential Transcription Factor

1993 • 63 citations

Activation of mouse peritoneal macrophages by monoclonal antibodies to Mac-1 (complement receptor type 3).

1987 • 62 citations

The TIS11 Primary Response Gene Is a Member of a Gene Family That Encodes Proteins with a Highly Conserved Sequence Containing an Unusual Cys-His Repeat

1991 • 52 citations

Analysis of cell ploidy in histological sections of mouse tissues by DNA-DNA in situ hybridization with digoxigenin-labelled probes

1993 • 50 citations

Mitogens stimulate the rapid nuclear to cytosolic translocation of tristetraprolin, a potential zinc-finger transcription factor

1996 • 35 citations

Haematologic effects of TNF

1993 • 30 citations

Analysis of autoantibody production in SCID-systemic lupus erythematosus (SLE) chimeras

1992 • 28 citations

Drug‐induced alterations of tumor necrosis factor‐mediated cytotoxicity: Discrimination of early versus late stage action

1990 • 21 citations

Gene transfer and bone marrow transplantation with special reference to Gaucher's disease.

1993 • 17 citations

Inhibition of skin xenograft rejection by depleting T-cell receptor alpha beta-bearing cells without T-cell receptor gamma delta-bearing cells or natural killer cells by monoclonal antibody.

1994 • 9 citations

Increased circulating CSF-1 (M-CSF) in myeloproliferative disease: association with myeloid metaplasia and peripheral bone marrow extension

1989 • 8 citations

Autoimmunity and Autoimmune Diseases

2023 • 8 citations

Cells expressing human glucocerebrosidase from a retroviral vector repopulate macrophages and central nervous system microglia after murine bone marrow transplantation

1994 • 7 citations

Expression of human glucocerebrosidase in murine macrophages: identification of efficient retroviral vectors.

1994 • 6 citations

In Vitro Assays for Mouse Lymphocyte Function

2006 • 5 citations

Agnogenic Myeloid Metaplasia

1977 • 1 citations