Tumor necrosis factor alpha modifies agonist-dependent responses in human neutrophils by inducing the synthesis and myristoylation of a specific protein kinase C substrate.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Activation of human polymorphonuclear neutrophil functions by interferon-gamma and tumor necrosis factors.

1985 • 922 citations

Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes.

1987 • 823 citations

Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide. Evidence for increased activity of the superoxide-producing enzyme.

1984 • 612 citations

Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator

1985 • 566 citations

Mechanism of neutrophil activation by NAF, a novel monocyte‐derived peptide agonist

1988 • 320 citations

Molecular cloning, characterization, and expression of a cDNA encoding the "80- to 87-kDa" myristoylated alanine-rich C kinase substrate: a major cellular substrate for protein kinase C.

1989 • 318 citations

Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst.

1986 • 294 citations

Enhancement of neutrophil superoxide production by preincubation with recombinant human tumor necrosis factor.

1987 • 292 citations

Multiple phosphorylation sites in protein I and their differential regulation by cyclic AMP and calcium.

1979 • 284 citations

Protein kinase C-stimulated phosphorylation in vitro of a Mr 80,000 protein phosphorylated in response to phorbol esters and growth factors in intact fibroblasts. Distinction from protein kinase C and prominence in brain.

1986 • 277 citations

Phosphorylation-regulated calmodulin binding to a prominent cellular substrate for protein kinase C

1989 • 241 citations

Stimulus-dependent myristoylation of a major substrate for protein kinase C

1988 • 216 citations

Bacterial lipopolysaccharides prime macrophages for enhanced release of arachidonic acid metabolites.

1986 • 211 citations

Phorbol esters cause sequential activation and deactivation of complement receptors on polymorphonuclear leukocytes.

1986 • 206 citations

Activation of neutrophil NADPH oxidase in a cell-free system. Partial purification of components and characterization of the activation process.

1987 • 202 citations

Neutrophil Activation by Recombinant Cytokines

1989 • 199 citations

Widespread occurrence of "87 kDa," a major specific substrate for protein kinase C.

1986 • 176 citations

Two transduction sequences are necessary for neutrophil activation by receptor agonists.

1988 • 172 citations

Gamma interferon is able to enhance the oxidative metabolism of human neutrophils

1986 • 166 citations

Inhibition by calmodulin of calcium/phospholipid-dependent protein phosphorylation.

1984 • 151 citations

Phosphorylation of an acidic mol. wt. 80 000 cellular protein in a cell-free system and intact Swiss 3T3 cells: a specific marker of protein kinase C activity.

1986 • 147 citations

The 87-kDa protein, a major specific substrate for protein kinase C: purification from bovine brain and characterization.

1987 • 138 citations

Protein phosphorylation in nerve terminals: comparison of calcium/calmodulin-dependent and calcium/diacylglycerol-dependent systems

1988 • 122 citations

Purification and characterization of an Mr 87,000 protein kinase C substrate from rat brain.

1987 • 117 citations

Staurosporine inhibits the respiratory burst and induces exocytosis in human neutrophils

1989 • 98 citations

Bacterial lipopolysaccharides, phorbol myristate acetate, and zymosan induce the myristoylation of specific macrophage proteins.

1986 • 88 citations

Environmental Nonhuman Sources of Leprosy

1987 • 75 citations

Acylation of cellular proteins with endogenously synthesized fatty acids

1986 • 73 citations

Platelet-activating factor production in human neutrophils by sequential stimulation with granulocyte-macrophage colony-stimulating factor and the chemotactic factors C5A or formyl-methionyl-leucyl-phenylalanine.

1989 • 67 citations

RNA and protein synthesis in human peripheral blood polymorphonuclear leukocytes.

1979 • 67 citations

SEQUENCES OF INTEREST: Molecular Cloning, Sequence, and Expression of a cDNA Encoding the Chicken Myristoylated Alanine-Rich C Kinase Substrate (MARCKS)

1989 • 65 citations

Bacterial Lipopolysaccharide Regulates the Phosphorylation of the 68K Protein Kinase C Substrate in Macrophages

1989 • 64 citations

Protein synthesis dependent and independent mechanisms of neutrophil emigration. Different mechanisms of inflammation in rabbits induced by interleukin-1, tumor necrosis factor alpha or endotoxin versus leukocyte chemoattractants.

1989 • 58 citations

Platelet-activating factor as a stimulus of exocytosis in human neutrophils

1986 • 51 citations

Ernst Klenk Lecture, November 1985. Intracellular signalling through inositol trisphosphate and diacylglycerol.

1986 • 30 citations

Ernst Klenk Lecture, November 1985. Intracellular signalling through inositol trisphosphate and diacylglycerol.

1986 • 18 citations