Disruption of the MacMARCKS gene prevents cranial neural tube closure and results in anencephaly.

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1992 • 3,907 citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1991 • 1,317 citations

Protein kinase C - a question of specificity

1994 • 958 citations

Teratocarcinomas and embryonic stem cells : a practical approach

1987 • 878 citations

Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds

1993 • 800 citations

Nested expression domains of four homeobox genes in developing rostral brain

1992 • 794 citations

MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium–calmodulin

1992 • 728 citations

A mouse model of Greig cephalo–polysyndactyly syndrome: the extra–toesJ mutation contains an intragenic deletion of the Gli3 gene

1993 • 715 citations

Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects.

1995 • 702 citations

splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3

1991 • 664 citations

twist is required in head mesenchyme for cranial neural tube morphogenesis.

1995 • 595 citations

A subset of p53-deficient embryos exhibit exencephaly

1995 • 577 citations

The MARCKS family of cellular protein kinase C substrates.

1993 • 484 citations

The Marcks brothers: A family of protein kinase C substrates

1992 • 474 citations

Evidence for multi‐site closure of the neural tube in humans

1993 • 393 citations

Mechanisms of neurulation: traditional viewpoint and recent advances

1990 • 392 citations

Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst.

1994 • 372 citations

The embryonic development of mammalian neural tube defects

1990 • 337 citations

Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation.

1995 • 329 citations

A role for MARCKS, the alpha isozyme of protein kinase C and myosin I in zymosan phagocytosis by macrophages.

1995 • 303 citations

MARCKS deficiency in mice leads to abnormal brain development and perinatal death.

1995 • 291 citations

Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes.

1995 • 258 citations

Expression of the homeo box-containing gene En-2 delineates a specific region of the developing mouse brain.

1988 • 225 citations

A genetic and molecular model for flower development in Arabidopsis thaliana

1991 • 218 citations

Whole-mount in situ hybridization in the mouse embryo: gene expression in three dimensions

1993 • 212 citations

Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctate structures in macrophage filopodia.

1990 • 195 citations

Neural tube defects.

1988 • 155 citations

In situ hybridization detection of trka mRNA in brain: Distribution, colocalization with p75^NGFR and up‐regulation by nerve growth factor

1994 • 155 citations

MacMARCKS, a novel member of the MARCKS family of protein kinase C substrates

1992 • 120 citations

Intermittent pattern of neural tube closure in two strains of mice

1993 • 119 citations

Neurulation in the mouse: Manner and timing of neural tube closure

1989 • 115 citations

Developmental study of neural tube closure in a mouse stock with a high incidence of exencephaly

1989 • 93 citations

A reexamination of the role of microfilaments in neurulation in the chick embryo

1988 • 93 citations

The role of microfilaments in cranial neurulation in rat embryos: effects of short-term exposure to cytochalasin D

1985 • 87 citations

Multiple sites of anterior neural tube closure in humans: evidence from anterior neural tube defects (anencephaly).

1995 • 86 citations

On the morphogenesis of the early rudiments of the developing central nervous system.

1982 • 80 citations

MacMARCKS Mutation Blocks Macrophage Phagocytosis of Zymosan

1995 • 75 citations

Characteristics of the F52 protein, a MARCKS homologue.

1992 • 72 citations

Intrinsic and extrinsic factors in the mechanism of neurulation: effect of curvature of the body axis on closure of the posterior neuropore

1993 • 68 citations

SEQUENCES OF INTEREST: Molecular Cloning, Sequence, and Expression of a cDNA Encoding the Chicken Myristoylated Alanine-Rich C Kinase Substrate (MARCKS)

1989 • 65 citations

Further evidence of extrinsic forces in bending of the neural plate

1991 • 55 citations

Nucleotide Sequence, Expression, and Chromosomal Mapping of Mrp and Mapping of Five Related Sequences

1993 • 39 citations

Stimulus-dependent Phosphorylation of MacMARCKS, a Protein Kinase C Substrate, in Nerve Termini and PC12 Cells

1996 • 25 citations

Cell movements driving neurulation in avian embryos.

1991 • 9 citations