The role of C/EBPbeta in mammary gland development and breast cancer.

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

CCAAT/enhancer-binding proteins: structure, function and regulation

2002 • 1,355 citations

A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the sam mRNA

1991 • 1,019 citations

Impaired Energy Homeostasis in C/EBPα Knockout Mice

1995 • 925 citations

Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins.

1995 • 922 citations

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia

2001 • 900 citations

Biological Role of the CCAAT/Enhancer-binding Protein Family of Transcription Factors

1998 • 799 citations

Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene

1997 • 776 citations

The Role of C/EBP Genes in Adipocyte Differentiation

1998 • 736 citations

Structure and function of aquaporin water channels

2000 • 699 citations

Dissociation between steroid receptor expression and cell proliferation in the human breast.

1997 • 623 citations

Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages

1995 • 532 citations

Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice.

1995 • 418 citations

Translational control of C/EBP alpha and C/EBP beta isoform expression

2000 • 403 citations

Signaling Pathways in Mammary Gland Development

2001 • 396 citations

An essential role for C/EBPβ in female reproduction

1997 • 387 citations

CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials.

1993 • 372 citations

Pattern of distribution of cells positive for estrogen receptor α and progesterone receptor in relation to proliferating cells in the mammary gland

1999 • 356 citations

Interaction and functional collaboration of p300 and C/EBPβ

1997 • 339 citations

The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factor.

1992 • 324 citations

A C/EBPβ Isoform Recruits the SWI/SNF Complex to Activate Myeloid Genes

1999 • 308 citations

DNA Binding Specificity of the CCAAT/Enhancer-binding Protein Transcription Factor Family

1996 • 300 citations

CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy.

1998 • 274 citations

The C/EBPβ transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland

1998 • 260 citations

C/EBPβ, but not C/EBPα, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mouse mammary gland

1998 • 254 citations

CRP2 (C/EBP beta) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity.

1995 • 230 citations

Novel mechanism of C/EBP beta (NF-M) transcriptional control: activation through derepression.

1994 • 225 citations

Human and Murine Phenotypes Associated with Defects in Cation-Chloride Cotransport

2002 • 219 citations

REGULATION OF MILK PROTEIN GENE EXPRESSION

1999 • 217 citations

A Nuclear Factor for Interleukin-6 Expression (NF-IL6) and the Glucocorticoid Receptor Synergistically Activate Transcription of the Rat α1-Acid Glycoprotein Gene via Direct Protein-Protein Interaction

1993 • 215 citations

Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6.

1996 • 213 citations

Mouse embryonic mammogenesis as a model for the molecular regulation of pattern formation

2003 • 203 citations

CCAAT/enhancer binding protein-β is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling

2001 • 196 citations

CREB Controls LAP/C/EBPβ Transcription

1997 • 189 citations

C/EBPβ (CCAAT/Enhancer Binding Protein) Controls Cell Fate Determination during Mammary Gland Development

2000 • 156 citations

McBindall—A Better Name for CCAAT/Enhancer Binding Proteins?

2001 • 156 citations

STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPbeta

2003 • 154 citations

C/EBPβ Modulates the Early Events of Keratinocyte Differentiation Involving Growth Arrest and Keratin 1 and Keratin 10 Expression

1999 • 149 citations

Roles of CCAAT/Enhancer-binding Proteins in Regulation of Liver Regenerative Growth

1998 • 145 citations

Overexpression of C/EBP -LIP, a Naturally Occurring, Dominant-Negative Transcription Factor, in Human Breast Cancer

1997 • 137 citations

Transcription Factors C/EBPα, C/EBPβ, and CHOP (Gadd153) Expressed During the Differentiation Program of Keratinocytes In Vitro and In Vivo

1998 • 136 citations

Developmentally and hormonally regulated CCAAT/enhancer-binding protein isoforms influence beta-casein gene expression.

1995 • 128 citations

The C/EBP family of transcription factors in the liver and other organs

1998 • 122 citations

CCAAT/enhancer binding protein beta (C/EBPβ)-2 transforms normal mammary epithelial cells and induces epithelial to mesenchymal transition in culture

2003 • 121 citations

Increased expression of the transcription factors CCAAT-enhancer binding protein-? (C/EB?) and C/EBP? (CHOP) correlate with invasiveness of human colorectal cancer

2000 • 120 citations

Expression of a translationally regulated, dominant-negative CCAAT/enhancer-binding protein beta isoform and up-regulation of the eukaryotic translation initiation factor 2alpha are correlated with neoplastic transformation of mammary epithelial cells.

1996 • 112 citations

C/EBPα Regulates Generation of C/EBPβ Isoforms through Activation of Specific Proteolytic Cleavage

1999 • 109 citations

Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium.

1990 • 106 citations

Disruption of Steroid and Prolactin Receptor Patterning in the Mammary Gland Correlates with a Block in Lobuloalveolar Development

2002 • 106 citations

Keratin 10 Gene Expression during Differentiation of Mouse Epidermis Requires Transcription Factors C/EBP and AP-2

1999 • 105 citations

Role of the Isoforms of CCAAT/Enhancer-binding Protein in the Initiation of Phosphoenolpyruvate Carboxykinase (GTP) Gene Transcription at Birth

1997 • 105 citations

CCAAT/enhancer binding proteins in normal mammary development and breast cancer

2002 • 104 citations

Interleukin-6-induced Tethering of STAT3 to the LAP/C/EBPβ Promoter Suggests a New Mechanism of Transcriptional Regulation by STAT3

2001 • 103 citations

Transcriptional and spatiotemporal regulation of prolactin receptor mRNA and cooperativity with progesterone receptor function during ductal branch growth in the mammary gland

2001 • 101 citations

The expression of CCAAT/enhancer binding protein (C/EBP) in the human ovary in vivo: specific increase in C/EBPβ during epithelial tumour progression

1999 • 99 citations

A role for CCAAT/enhancer binding protein beta-liver-enriched inhibitory protein in mammary epithelial cell proliferation.

2001 • 98 citations

Cooperative Effects of STAT5 (Signal Transducer and Activator of Transcription 5) and C/EBP β (CCAAT/Enhancer-Binding Protein-β) onβ -Casein Gene Transcription Are Mediated by the Glucocorticoid Receptor

2001 • 95 citations

Calreticulin Interacts with C/EBPα and C/EBPβ mRNAs and Represses Translation of C/EBP Proteins

2002 • 94 citations

CCAAT/enhancer binding proteins are critical components of the transcriptional regulation of hematopoiesis (Review).

1998 • 92 citations

T<scp>HE</scp> R<scp>OLE OF</scp> C/EBP <scp>IN</scp> N<scp>UTRIENT AND</scp> H<scp>ORMONAL</scp> R<scp>EGULATION OF</scp> G<scp>ENE</scp> E<scp>XPRESSION</scp>

2001 • 91 citations

Functional Association of PR and CCAAT/Enhancer-Binding Proteinβ Isoforms: Promoter-Dependent Cooperation between PR-B and Liver-Enriched Inhibitory Protein, or Liver-Enriched Activatory Protein and PR-A in Human Endometrial Stromal Cells

2002 • 88 citations

CCAAT/Enhancer-binding Protein β Plays a Regulatory Role in Differentiation and Apoptosis of Neuroblastoma Cells

2002 • 85 citations

Jak2 Is an Essential Tyrosine Kinase Involved in Pregnancy-Mediated Development of Mammary Secretory Epithelium

2002 • 80 citations

Progesterone receptors in the mouse mammary duct: distribution and developmental regulation.

1996 • 76 citations

Characterization of C/EBPβ isoforms in normal versus neoplastic mammary epithelial cells

2001 • 72 citations

Generation of Truncated C/EBPβ Isoforms by in VitroProteolysis

2000 • 71 citations

Lactation status influences expression of CCAAT/enhancer binding protein isoform mRNA in the mouse mammary gland

1998 • 58 citations

C/EBP-β, C/EBP-δ, PU.1, AML1 genes: mutational analysis in 381 samples of hematopoietic and solid malignancies

2002 • 57 citations

Autoregulation enables different pathways to control CCAAT/enhancer binding protein β (C/EBPβ) transcription

2001 • 55 citations

Proteotyping of Mammary Tissue from Transgenic and Gene Knockout Mice with Immunohistochemical Markers: a Tool To Define Developmental Lesions

2003 • 52 citations

Mouse Mammary Epithelial Cells Express the Na-K-Cl Cotransporter, NKCC1: Characterization, Localization, and Involvement in Ductal Development and Morphogenesis

2002 • 51 citations

The CCAAT/enhancer binding protein (C/EBPα) gene (CEBPA) maps to human chromosome 19q13.1 and the related nuclear factor NF-IL6 (C/EBPβ) gene (CEBPB) maps to human chromosome 20q13.1

1992 • 50 citations

Composite response elements mediate hormonal and developmental regulation of milk protein gene expression.

1998 • 47 citations

Immunophenotypic properties and estrogen dependency of budding cell structures in the developing mouse mammary gland

1993 • 46 citations

Transcription of a Minimal Promoter from the NF-IL6 Gene Is Regulated by CREB/ATF and SP1 Proteins in U937 Promonocytic Cells

1998 • 42 citations

Expression of the genes encoding CCAAT-enhancer binding protein isoforms in the mouse mammary gland during lactation and involution

1998 • 42 citations

Expression and function of CCAAT/enhancer binding proteinβ (C/EBPβ) LAP and LIP isoforms in mouse mammary gland, tumors and cultured mammary epithelial cells

2001 • 41 citations

Nulliparous CCAAT/Enhancer Binding Proteinδ (C/EBPδ) Knockout Mice Exhibit Mammary Gland Ductal Hyperlasia

2003 • 41 citations

Autoregulated Induction of the Acute-Phase Response Transcription Factor Gene,agp/ebp

1995 • 36 citations

Progesterone regulation of reproductive function through functionally distinct progesterone receptor isoforms.

2002 • 30 citations

The v-Myb oncoprotein activates C/EBPβ expression by stimulating an autoregulatory loop at the C/EBPβ promoter

1999 • 27 citations

Experimental mouse genetics – answering fundamental questions about mammary gland biology

2001 • 26 citations

Mouse Chromosomal Location of the CCAAT/Enhancer Binding Proteins C/EBPβ (Cebpb), C/EBPδ (Cebpd), and CRP1 (Cebpe)

1995 • 26 citations

Anomalies in the hormonal status of athymic nude mice

1990 • 26 citations

Organization of the promoter region of the human NF-IL6 gene

2002 • 20 citations

Transcriptional Activation of C/EBPβGene by c-Jun and ATF2

2002 • 18 citations

Molecular Characterization of the Xenopus CCAAT-Enhancer Binding Protein β Gene Promoter

2001 • 17 citations