Transcription Factors C/EBPα, C/EBPβ, and CHOP (Gadd153) Expressed During the Differentiation Program of Keratinocytes In Vitro and In Vivo

Calcium regulation of growth and differentiation of mouse epidermal cells in culture

1980 • 1,810 citations

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.

1992 • 1,156 citations

A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the sam mRNA

1991 • 1,019 citations

Isolation of a recombinant copy of the gene encoding C/EBP.

1988 • 1,003 citations

Transcriptional regulation

1991 • 893 citations

Stress-Induced Phosphorylation and Activation of the Transcription Factor CHOP (GADD153) by p38 MAP Kinase

1996 • 893 citations

Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies

1982 • 777 citations

Epidermal differentiation: the bare essentials.

1990 • 651 citations

Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

1989 • 641 citations

Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro.

1989 • 569 citations

Homologous recognition of a promoter domain common to the MSV LTR and the HSV tk gene

1986 • 562 citations

CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells.

1989 • 488 citations

Ectopic expression of the CCAAT/enhancer-binding protein alpha promotes the adipogenic program in a variety of mouse fibroblastic cells.

1994 • 450 citations

CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program.

1994 • 433 citations

cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to trans-locate to the nucleus and induce c-fos transcription.

1991 • 388 citations

CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials.

1993 • 372 citations

Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain

1993 • 345 citations

Dimerization specificity of the leucine zipper-containing bZIP motif on DNA binding: prediction and rational design.

1993 • 335 citations

Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes.

1992 • 324 citations

Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization

1991 • 312 citations

Stress-Induced Binding of the Transcription Factor CHOP to a Novel DNA Control Element

1996 • 305 citations

Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6

1992 • 299 citations

A liver-specific DNA-binding protein recognizes multiple nucleotide sites in regulatory regions of transthyretin, alpha 1-antitrypsin, albumin, and simian virus 40 genes.

1988 • 239 citations

The dynamic state of heat shock proteins in chicken embryo fibroblasts.

1986 • 227 citations

BALB and kirsten murine sarcoma viruses alter growth and differentiation of EGF-dependent BALB/c mouse epidermal keratinocyte lines

1983 • 224 citations

Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis.

1988 • 182 citations

The Epidermis: Genes On – Genes Off

1997 • 181 citations

Stratification, specialization, and proliferation of primary keratinocyte cultures. Evidence of a functioning in vitro epidermal cell system.

1978 • 179 citations

Evidence for Posttranscriptional Regulation of C/EBPα and C/EBPβ Isoform Expression during the Lipopolysaccharide-Mediated Acute-Phase Response†

1996 • 155 citations

Tumor necrosis factor-induced reversal of adipocytic phenotype of 3T3-L1 cells is preceded by a loss of nuclear CCAAT/enhancer binding protein (C/EBP).

1992 • 149 citations

Pancreatic β-Cell-specific Repression of Insulin Gene Transcription by CCAAT/Enhancer-binding Protein β

1997 • 123 citations

Isolation and characterization of the hamster gadd153 gene. Activation of promoter activity by agents that damage DNA.

1990 • 120 citations

Proteolytic modification of acidic and basic keratins during terminal differentiation of mouse and human epidermis

1984 • 116 citations

Signal Transduction for Proliferation and Differentiation in Keratinocytes

1988 • 96 citations

Differential Patterns of Expression of Three C/EBP Isoforms, HNF-1, and HNF-4 after Partial Hepatectomy in Rats

1993 • 91 citations

CCAAT/Enhancer-binding Proteins

1999 • 91 citations

Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene.

1985 • 91 citations

Evidence for Specific Proteolytic Cleavage of the N-Terminal Domain of Human Profilaggrin During Epidermal Differentiation

1997 • 81 citations

DNA-Binding Specificity of the PAR Basic Leucine Zipper Protein VBP Partially Overlaps Those of the C/EBP and CREB/ATF Families and Is Influenced by Domains That Flank the Core Basic Region

1995 • 68 citations

[15] Very-high-resolution two-dimensional electrophoretic separation of proteins on giant gels

1983 • 68 citations

Drosophila C/EBP: a tissue-specific DNA-binding protein required for embryonic development.

1992 • 67 citations

Differential effects of heat shock and UVB light upon stress protein expression in epidermal keratinocytes

1992 • 64 citations

Heat Shock Modulates UVB-Induced Cell Death in Human Epidermal Keratinocytes: Evidence for a Hyperthermia-Inducible Protective Response

1994 • 62 citations

Keratin Polypeptide Analysis in Fetal and in Terminally Differentiating Newborn Mouse Epidermis

1982 • 61 citations

C/EBPbeta is a negative regulator of human papillomavirus type 11 in keratinocytes

1996 • 48 citations

Hyperthermia induces resistance to ultraviolet light B in primary and immortalized epidermal keratinocytes.

1993 • 48 citations

Regulation of the Pro-B-Cell-Specific Enhancer of the Id1 Gene Involves the C/EBP Family of Proteins

1997 • 33 citations

Rapid characterization of growth-arrest genes in transient transfection assays.

1995 • 15 citations

A microanalytical protein assay using laser densitometry

1984 • 11 citations