Functional and biochemical interactions of Wnts with FrzA, a secreted Wnt antagonist
Data up to Jan 2025
Total Citations Per Year
Abstract
References (82)
Molecular Cloning: A Laboratory Manual
2001 • 133,517 citations
Molecular cloning: A laboratory manual
1990 • 85,659 citations
A new technique for the assay of infectivity of human adenovirus 5 DNA
1973 • 9,740 citations
Normal Table of Xenopus Laevis (Daudin)
1958 • 4,561 citations
Normal table of Xenopus laevis (Daudin)
1995 • 2,955 citations
Functional interaction of β-catenin with the transcription factor LEF-1
1996 • 2,847 citations
Wnt signaling: a common theme in animal development
1997 • 2,579 citations
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.
1985 • 2,456 citations
Appendix G: In Situ Hybridization: An Improved Whole-Mount Method for Xenopus Embryos
1991 • 2,082 citations
XTcf-3 Transcription Factor Mediates β-Catenin-Induced Axis Formation in Xenopus Embryos
1996 • 1,827 citations
A major developmental transition in early xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage
1982 • 1,635 citations
Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs
1984 • 1,533 citations
A new member of the frizzled family from Drosophila functions as a Wingless receptor
1996 • 1,489 citations
Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor.
1993 • 1,391 citations
Armadillo Coactivates Transcription Driven by the Product of the Drosophila Segment Polarity Gene dTCF
1997 • 1,201 citations
Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes
1994 • 1,114 citations
Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4
1994 • 1,056 citations
Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction
1991 • 980 citations
The Mouse Locus Encodes Axin, an Inhibitor of the Wnt Signaling Pathway That Regulates Embryonic Axis Formation
1997 • 908 citations
Nuclear localization of β-catenin by interaction with transcription factor LEF-1
1996 • 864 citations
Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer
1996 • 757 citations
Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus
1995 • 731 citations
Frzb-1 Is a Secreted Antagonist of Wnt Signaling Expressed in the Spemann Organizer
1997 • 725 citations
Dorsalizing signal Wnt-7a required for normal polarity of D–V and A–P axes of mouse limb
1995 • 719 citations
Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos
1997 • 663 citations
Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center
1991 • 651 citations
Overexpression of cadherins and underexpression of ?-catenin inhibit dorsal mesoderm induction in early Xenopus embryos
1994 • 647 citations
A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors
1997 • 573 citations
Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development
1992 • 573 citations
Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling.
1995 • 545 citations
Wnt Signaling Polarizes an Early C. elegans Blastomere to Distinguish Endoderm from Mesoderm
1997 • 525 citations
Frzb, a Secreted Protein Expressed in the Spemann Organizer, Binds and Inhibits Wnt-8
1997 • 508 citations
Injected Wnt RNA induces a complete body axis in Xenopus embryos
1991 • 501 citations
pangolinencodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila
1997 • 494 citations
A Member of the Frizzled Protein Family Mediating Axis Induction by Wnt-5A
1997 • 493 citations
Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos
1995 • 492 citations
A frizzled homolog functions in a vertebrate Wnt signaling pathway
1996 • 471 citations
Induction of the LIM homeobox gene Lmx1 by WNT6a establishes dorsoventral pattern in the vertebrate limb
1995 • 469 citations
Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus.
1993 • 449 citations
The Xenopus homologue of Otx2 is a maternal homeobox gene that demarcates and specifies anterior body regions
1995 • 435 citations
Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action
1997 • 411 citations
Analysis of Dishevelled signalling pathways during Xenopus development
1996 • 402 citations
The dishevelled protein is modified by wingless signaling in Drosophila.
1995 • 389 citations
MyoD expression in the forming somites is an early response to mesoderm induction in Xenopus embryos.
1989 • 374 citations
Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderminducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis
1991 • 373 citations
The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos.
1992 • 371 citations
A Large Family of Putative Transmembrane Receptors Homologous to the Product of the Drosophila Tissue Polarity Gene frizzled
1996 • 369 citations
A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains
1989 • 367 citations
Organizer-Specific Homeobox Genes in Xenopus laevis Embryos
1991 • 349 citations
Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos.
1996 • 345 citations
A nodal-related gene defines a physical and functional domain within the Spemann organizer
1995 • 332 citations
Xwnt-5A: a maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis
1993 • 330 citations
SARPs: A family of secreted apoptosis-related proteins
1997 • 327 citations
Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos.
1995 • 321 citations
Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: Dorsal signals regulate anteroposterior patterning
1995 • 318 citations
Identification of Distinct Classes and Functional Domains of Wnts through Expression of Wild-Type and Chimeric Proteins in Xenopus Embryos
1995 • 314 citations
Primary Structure and Tissue Distribution of FRZB, a Novel Protein Related to Drosophila Frizzled, Suggest a Role in Skeletal Morphogenesis
1996 • 243 citations
Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3
1995 • 233 citations
Specification of the Anteroposterior Neural Axis through Synergistic Interaction of the Wnt Signaling Cascade withnogginandfollistatin
1995 • 222 citations
Overlapping Expression of Xwnt-3A and Xwnt-1 in Neural Tissue of Xenopus laevis Embryos
1993 • 202 citations
Biological activity of soluble wingless protein in cultured Drosophila imaginal disc cells
1994 • 194 citations
Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled
1995 • 185 citations
The genetic basis of patterned baldness in Drosophila
1994 • 182 citations
The genetic control of tissue polarity in Drosophila
1992 • 175 citations
Developmental regulation of a gastrula-specific gene injected into fertilized Xenopus eggs.
1985 • 173 citations
Wnt genes and vertebrate development
1994 • 173 citations
Anterior axis duplication in Xenopus induced by the over-expression of the cadherin-binding protein plakoglobin.
1995 • 166 citations
Sizzled: a secreted Xwnt8 antagonist expressed in the ventral marginal zone of Xenopus embryos
1997 • 162 citations
Induction of Kidney Epithelial Morphogenesis by Cells Expressing Wnt-1
1994 • 157 citations
Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase.
1994 • 122 citations
Frzb-1, an Antagonist of Wnt-1 and Wnt-8, Does Not Block Signaling by Wnts -3A, -5A, or -11
1997 • 111 citations
Two homologs of the Drosophila polarity gene frizzled (fz) are widely expressed in mammalian tissues.
1992 • 103 citations
Specific modulation of ectodermal cell fates in Xenopus embryos by glycogen synthase kinase
1995 • 100 citations
Identification of soluble forms of the fibroblast growth factor receptor in blood.
1994 • 97 citations
A novel homeobox gene PV.1 mediates induction of ventral mesoderm in Xenopus embryos.
1996 • 95 citations
Xwnt-8 and lithium can act upon either dorsal mesodermal or neurectodermal cells to cause a loss of forebrain in Xenopus embryos
1997 • 89 citations
Characterization of Novel Secreted and Membrane Proteins Isolated by the Signal Sequence Trap Method
1996 • 83 citations
Serpentine Proteins Slither into the Wingless and Hedgehog Fields
1996 • 74 citations
Fritz: a secreted frizzled-related protein that inhibits Wnt activity
1997 • 66 citations
Graded amounts of Xenopus dishevelled specify discrete anteroposterior cell fates in prospective ectoderm
1997 • 59 citations
Functional Conservation of the Wnt Signaling Pathway Revealed by Ectopic Expression of Drosophila dishevelled in Xenopus
1995 • 58 citations
Mesoderm formation in Xenopus ectodermal explants overexpressing Xwnt8: evidence for a cooperating signal reaching the animal pole by gastrulation
1993 • 45 citations