Two homologs of the Drosophila polarity gene frizzled (fz) are widely expressed in mammalian tissues.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

A Method for Isolation of Intact, Translationally Active Ribonucleic Acid

1983 • 1,469 citations

MODEL SYSTEMS FOR THE STUDY OF SEVEN-TRANSMEMBRANE-SEGMENT RECEPTORS

1991 • 1,357 citations

Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases

1991 • 1,327 citations

A G Protein-Linked Receptor for Parathyroid Hormone and Parathyroid Hormone-Related Peptide

1991 • 1,230 citations

Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium.

1992 • 1,009 citations

The Effect of Calcium-Regulating Hormones and Prostaglandins on Bone Resorption by Osteoclasts Disaggregated from Neonatal Rabbit Bones*

1985 • 419 citations

A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains

1989 • 367 citations

Directional non-cell autonomy and the transmission of polarity information by the frizzled gene of Drosophila

1987 • 351 citations

A genetic analysis of the determination of cuticular polarity during development inDrosophila melanogaster

1982 • 344 citations

Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine-kinase receptor

1991 • 298 citations

Molecular structure of frizzled, a Drosophila tissue polarity gene.

1990 • 72 citations

Current developments in G-protein-coupled receptors

1991 • 54 citations

Multiple sequence alignment of protein families showing low sequence homology: a methodological approach using database pattern-matching discriminators for G-protein-linked receptors

1991 • 53 citations

Allelic variation at the frizzled locus of Drosophila

1987 • 42 citations