Regulation of I _Cl,swell in neuroblastoma cells by G protein signaling pathways

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Rho GTPases and signaling networks

1997 • 2,380 citations

Rho GTPases and their effector proteins

2000 • 1,941 citations

Functional Significance of Cell Volume Regulatory Mechanisms

1998 • 1,871 citations

TENSEGRITY: THE ARCHITECTURAL BASIS OF CELLULAR MECHANOTRANSDUCTION

1997 • 1,550 citations

G PROTEIN βγ SUBUNITS

1997 • 834 citations

Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis

2000 • 707 citations

Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor

1997 • 652 citations

Cellular and molecular physiology of volume-sensitive anion channels

1996 • 620 citations

Molecular identification of a volume-regulated chloride channel

1997 • 443 citations

Rho as a regulator of the cytoskeleton

1995 • 386 citations

Rho effectors and reorganization of actin cytoskeleton

1997 • 379 citations

Modulation of GTPase activity of G proteins by fluid shear stress and phospholipid composition

1998 • 344 citations

Effectors for the Rho GTPases

1999 • 327 citations

Rho: theme and variations

1996 • 290 citations

Direct interaction of Gβγ with a C-terminal Gβγ-binding domain of the Ca ²⁺ channel α ₁ subunit is responsible for channel inhibition by G protein-coupled receptors

1997 • 246 citations

Physiological significance of volume-regulatory transporters

1999 • 244 citations

Rho proteins: Targets for bacterial toxins

1997 • 172 citations

Activation of the osmo-sensitive chloride conductance involves P21rho and is accompanied by a transient reorganization of the F-actin cytoskeleton.

1996 • 171 citations

Mitogen-Activated Protein and Tyrosine Kinases in the Activation of Astrocyte Volume-Activated Chloride Current

1998 • 166 citations

Volume-activated Cl− channels

1996 • 163 citations

The Tyrosine Kinase p56lck Mediates Activation of Swelling-induced Chloride Channels in Lymphocytes

1998 • 161 citations

Regulation of a swelling‐activated chloride current in bovine endothelium by protein tyrosine phosphorylation and G proteins

1998 • 160 citations

A Serine Residue in ClC-3 Links Phosphorylation–Dephosphorylation to Chloride Channel Regulation by Cell Volume

1999 • 159 citations

Glutamate Release through Volume-Activated Channels during Spreading Depression

1999 • 146 citations

Volume‐sensitive chloride conductance in bovine chromaffin cell membrane.

1992 • 141 citations

Role of Rho and Rho kinase in the activation of volume‐regulated anion channels in bovine endothelial cells

1999 • 140 citations

Biophysical Properties of ClC-3 Differentiate It from Swelling-activated Chloride Channels in Chinese Hamster Ovary-K1 Cells

2000 • 134 citations

Properties and glial origin of osmotic‐dependent release of taurine from the rat supraoptic nucleus

1998 • 130 citations

Activation of volume‐regulated chloride currents by reduction of intracellular ionic strength in bovine endothelial cells

1998 • 119 citations

The role of ClC‐3 in volume‐activated chloride currents and volume regulation in bovine epithelial cells demonstrated by antisense inhibition

2000 • 117 citations

Intracellular ionic strength regulates the volume sensitivity of a swelling-activated anion channel

1998 • 112 citations

Inhibition by anion channel blockers of ischemia-evoked release of excitotoxic and other amino acids from rat cerebral cortex

1997 • 105 citations

Swelling-Activated Chloride Current Is Persistently Activated in Ventricular Myocytes From Dogs With Tachycardia-Induced Congestive Heart Failure

1999 • 102 citations

Modulation of rat cardiac sodium channel by the stimulatory G protein α subunit

1999 • 101 citations

Perspective: Molecular Identity of the Outwardly Rectifying, Swelling-activated Anion Channel: Time to Reevaluate pICln

1998 • 90 citations

Cell swelling activates ATP-dependent voltage-gated chloride channels in M-1 mouse cortical collecting duct cells.

1996 • 88 citations

Cl- current activation in choroid plexus epithelial cells involves a G protein and protein kinase A

1994 • 87 citations

Modulation of a volume-regulated chloride current by F-actin

1995 • 87 citations

The swelling-activated chloride channel ClC-2, the chloride channel ClC-3, and ClC-5, a chloride channel mutated in kidney stone disease, are expressed in distinct subpopulations of renal epithelial cells.

1998 • 83 citations

Involvement of Stretch-Activated Cl⁻Channels in Ramification of Murine Microglia

1998 • 73 citations

Intracellular electrolytes regulate the volume set point of the organic osmolyte/anion channel VSOAC

1997 • 70 citations

GTP‐binding proteins mediate noradrenaline effects on calcium and chloride currents in rat portal vein myocytes.

1990 • 69 citations

Swelling-Activated Release of Excitatory Amino Acids in the Brain: Relevance for Pathophysiology

1998 • 69 citations

Kinetic and pharmacological properties of the calciumm-activated chloride-current in macrovascular endothelial cells

1997 • 69 citations

Novel chloride conductance in the membrane of bovine chromaffin cells activated by intracellular GTP gamma S.

1991 • 61 citations

Cardiac G _sα overexpression enhances L-type calcium channels through an adenylyl cyclase independent pathway

1998 • 60 citations

The volume-activated chloride current in human endothelial cells depends on intracellular ATP

1994 • 48 citations

Methods for imaging renal tubule cells

1986 • 48 citations

The volume-activated chloride current in endothelial cells from bovine pulmonary artery is not modulated by phosphorylation

1996 • 44 citations

ATP Dependence of the ICl, swell Channel Varies with Rate of Cell Swelling

1999 • 40 citations

Involvement of PKC‐α in regulatory volume decrease responses and activation of volume‐sensitive chloride channels in human cervical cancer HT‐3 cells

1998 • 37 citations

Modulation of dog atrial swelling-induced chloride current by cAMP: protein kinase A-dependent and -independent pathways.

1997 • 36 citations

The Cytoskeleton in Cell Volume Regulation

1998 • 34 citations

Modulation of volume‐sensitive Cl ^– channels and cell volume by actin filaments and microtubules in human cervical cancer HT‐3 cells

1999 • 34 citations

Ca²⁺‐sensing receptor‐mediated regulation of volume‐sensitive Cl⁻ channels in human epithelial cells

2000 • 29 citations

Protein phosphotyrosine phosphatase inhibitors suppress regulatory volume decrease and the volume-sensitive Cl - conductance in mouse fibroblasts

1999 • 29 citations

Pervanadate inhibits volume-sensitive chloride current in bovine chromaffin cells

1997 • 24 citations

GTPγS-induced actin polymerisation in vitro: ATP- and phosphoinositide independent signalling via Rho-family proteins and a plasma membrane- associated guanine nucleotide exchange factor

1998 • 22 citations

An Evaluation of Strategies Available for the Identification of GTP-Binding Proteins Required in Intracellular Signalling Pathways

1997 • 21 citations

A Ca 2+ -activated Whole-Cell Cl − Conductance In Human Placental Cytotrophoblast Cells Activated Via a G Protein

1996 • 19 citations

Neurotensin, bradykinin and somatostatin inhibit cAMP production in neuroblastoma N1E115 cells via both pertussis toxin sensitive and insensitive mechanisms

1989 • 18 citations

Ketoconazole blocks organic osmolyte efflux independently of its effect on arachidonic acid conversion

1994 • 16 citations

Molecular clues to mechanosensitivity

1993 • 13 citations