Glutamate Release through Volume-Activated Channels during Spreading Depression

Interplay between Cortical Spreading Depolarization and Seizures

2017 • 3,543 citations

SPREADING DEPRESSION OF ACTIVITY IN THE CEREBRAL CORTEX

1944 • 2,580 citations

FURTHER OBSERVATIONS ON THE SPREADING DEPRESSION OF ACTIVITY IN THE CEREBRAL CORTEX

1947 • 906 citations

Extracellular space structure revealed by diffusion analysis

1998 • 876 citations

Low extracellular magnesium induces epileptiform activity and spreading depression in rat hippocampal slices

1987 • 642 citations

Cellular and molecular physiology of volume-sensitive anion channels

1996 • 620 citations

Molecular identification of a volume-regulated chloride channel

1997 • 443 citations

Extracellular ionic variations during spreading depression

1978 • 387 citations

Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux

1993 • 331 citations

Evidence for a role of the N-methyl-d-aspartate (NMDA) receptor in cortical spreading depression in the rat

1988 • 321 citations

Imaging of synaptically evoked intrinsic optical signals in hippocampal slices

1991 • 302 citations

Imaging cell volume changes and neuronal excitation in the hippocampal slice

1994 • 302 citations

The Effect of MK-801 on Cortical Spreading Depression in the Penumbral Zone following Focal Ischaemia in the Rat

1992 • 290 citations

The Effect of Glutamate Receptor Blockade on Anoxic Depolarization and Cortical Spreading Depression

1992 • 276 citations

Imaging Spreading Depression and Associated Intracellular Calcium Waves in Brain Slices

1998 • 224 citations

Cloning and expression of a protein kinase C-regulated chloride channel abundantly expressed in rat brain neuronal cells

1994 • 223 citations

Intrinsic optical signals in rat neocortical slices measured with near- infrared dark-field microscopy reveal changes in extracellular space

1996 • 219 citations

The elusive transporters with a high affinity for glutamate

1993 • 195 citations

Mitogen-Activated Protein and Tyrosine Kinases in the Activation of Astrocyte Volume-Activated Chloride Current

1998 • 166 citations

Volume‐sensitive release of taurine from cultured astrocytes: Properties and mechanism

1990 • 155 citations

Mechanisms of spreading depression: a review of recent findings and a hypothesis

1992 • 150 citations

Release of taurine from astrocytes during potassium‐evoked swelling

1989 • 134 citations

Two mechanisms for spreading depression in the chicken retina

1978 • 134 citations

Role of neuronal synchronizing mechanisms in the propagation of spreading depression in the in vivo hippocampus

1994 • 132 citations

Changes in cortical extracellular space during spreading depression investigated with the electron microscope.

1967 • 126 citations

Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum

1988 • 113 citations

Release of [³H]-d-Aspartate from Primary Astrocyte Cultures in Response to Raised External Potassium

1996 • 112 citations

NMDA‐receptor blockers but not NBQX, an AMPA‐receptor antagonist, inhibit spreading depression in the rat brain

1992 • 107 citations

Pharmacological characterization of swelling-induced<scp>d</scp>-[³H]aspartate release from primary astrocyte cultures

1998 • 106 citations

Inhibition by anion channel blockers of ischemia-evoked release of excitotoxic and other amino acids from rat cerebral cortex

1997 • 105 citations

Regulatory volume decrease in cultured astrocytes. I. Potassium- and chloride-activated permeability

1994 • 103 citations

Inhibition of volume regulation and efflux of osmoregulatory amino acids by blockers of Cl− transport in cultured astrocytes

1993 • 101 citations

Regulatory volume decrease in cultured astrocytes. II. Permeability pathway to amino acids and polyols

1994 • 97 citations

Prolonged field bursts in the dentate gyrus: dependence on low calcium, high potassium, and nonsynaptic mechanisms

1992 • 94 citations

Whole-cell chloride currents in rat astrocytes accompany changes in cell morphology

1996 • 80 citations

Amino acid current through anion channels in cultured human glial cells

1995 • 78 citations

Cytoskeletal Actin Gates a Cl⁻Channel in Neocortical Astrocytes

1998 • 75 citations

Interstitial volume changes during spreading depression (SD) and SD-like hypoxic depolarization in hippocampal tissue slices

1994 • 75 citations

Role of calcium channels in spreading depression in rat hippocampal slices

1993 • 72 citations

Disruption of Mitochondrial Respiration Inhibits Volume-Regulated Anion Channels and Provokes Neuronal Cell Swelling

1998 • 72 citations

Inhibition of cortical spreading depression by L‐701,324, a novel antagonist at the glycine site of the N‐methyl‐D‐aspartate receptor complex

1996 • 71 citations

Interaction of phencyclidine with voltage-dependent potassium channels in cultured rat hippocampal neurons: comparison with block of the NMDA receptor-ionophore complex

1989 • 40 citations

A Glycine Site Antagonist, ZD9379, Reduces Number of Spreading Depressions and Infarct Size in Rats With Permanent Middle Cerebral Artery Occlusion

1998 • 37 citations

Suppression of Spreading Depression of Leão in Neocortex by an N-Methyl-D-Aspartate Receptor Antagonist

1992 • 33 citations

A comparison of (+) SK &amp; F 10047 and MK-801 on cortical spreading depression

1994 • 31 citations

Effects of glycine receptor antagonism on spreading depression in the rat

1994 • 24 citations

Inhibition by Cl? channel blockers of the volume-activated, diffusional mechanism of inositol transport in primary astrocytes in culture

1995 • 22 citations

Glutamate release in parabrachial nucleus and baroreflex alterations after vagal afferent activation

1997 • 20 citations

Channels for amino acids and metabolites activated by cell volume regulation.

1994 • 9 citations