Extracellular Signal-Regulated Kinases Modulate Capacitation of Human Spermatozoa1

The Physiology of Reproduction

1988 • 7,765 citations

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

1995 • 3,456 citations

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

1995 • 2,723 citations

cPLA2 is phosphorylated and activated by MAP kinase

1993 • 1,858 citations

Capacitation of mouse spermatozoa: I. Correlation between the capacitation state and protein tyrosine phosphorylation

1995 • 950 citations

Suppression of Integrin Activation: A Novel Function of a Ras/Raf-Initiated MAP Kinase Pathway

1997 • 501 citations

95 kd sperm proteins bind ZP3 and serve as tyrosine kinase substrates in response to zona binding

1989 • 341 citations

Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus

1993 • 328 citations

Requirements for Phosphorylation of Map Kinase During Meiosis in Xenopus Oocytes

1992 • 316 citations

Intracellular Calcium Accumulation and Responsiveness to Progesterone in Capacitating Human Spermatozoa

1991 • 304 citations

Relationship between calcium, cyclic AMP, ATP, and intracellular pH and the capacity of hamster spermatozoa to express hyperactivated motility

1989 • 203 citations

Multiple intracellular MAP kinase signaling cascades

1996 • 173 citations

Extracellular Calcium Negatively Modulates Tyrosine Phosphorylation and Tyrosine Kinase Activity during Capacitation of Human Spermatozoa1

1996 • 165 citations

Endothelin rapidly stimulates mitogen-activated protein kinase activity in rat mesangial cells

1992 • 163 citations

Role of membrane phosphotyrosine proteins in human spermatozoa! function

1991 • 152 citations

Stimulation of protein tyrosine phosphorylation by a progesterone receptor on the cell surface of human sperm.

1993 • 150 citations

Newly synthesized protein(s) must associate with p34cdc2 to activate MAP kinase and MPF during progesterone-induced maturation of Xenopus oocytes.

1995 • 144 citations

Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine macrophages by natural and synthetic bacterial products.

1993 • 133 citations

Evidence that a GABAA-Like Receptor is Involved in Progesterone-Induced Acrosomal Exocytosis in Mouse Spermatozoa1

1995 • 122 citations

Intracellular pH of bovine sperm increases during capacitation

1995 • 108 citations

p42 mitogen-activated protein kinase and p90 ribosomal S6 kinase are selectively phosphorylated and activated during thrombin-induced platelet activation and aggregation

1994 • 107 citations

Intracellular calcium increase and acrosome reaction in response to progesterone in human spermatozoa are correlated with in-vitro fertilization

1995 • 105 citations

Stimulation of protein tyrosine phosphorylation by platelet-activating factor and progesterone in human spermatozoa

1995 • 101 citations

Human sperm activation during capacitation and acrosome reaction Role of calcium protein phosphorylation and lipid remodelling pathways

1996 • 94 citations

Signal transduction events mediated by the BDNF receptor gp 145trkB in primary hippocampal pyramidal cell culture

1993 • 90 citations

Cell cycle reentry of mammalian fibroblasts is accompanied by the sustained activation of P44^mapk and P42^mapk isoforms in the G1 phase and their inactivation at the G1/s transition

1995 • 85 citations

Involvement of phosphatidylinositol 3‐kinase in the activation of extracellular signal‐regulated kinase by PDGF in hepatic stellate cells

1995 • 85 citations

Integrins and human reproduction

1996 • 84 citations

Progesterone stimulates p42 extracellular signal-regulated kinase (p42erk) in human spermatozoa

1998 • 83 citations

Cyclic AMP-dependent phosphorylation of epididymal mouse sperm proteins during capacitation in vitro: identification of an Mr 95 000 phosphotyrosine-containing protein

1993 • 69 citations

Stimulation of platelet-activating factor synthesis by progesterone and A23187 in human spermatozoa

1993 • 59 citations

Expression and function of ras proto-oncogene proteins in human sperm cells

1992 • 48 citations

Monoclonal antibodies which recognize equatorial segment epitopes presented de novo following the a23187-induced acrosome reaction of guinea pig sperm

1995 • 46 citations

Role of Human Sperm Phospholipase A2 in Fertilization: Effects of a Novel Inhibitor of Phospholipase A2 Activity on Membrane Perturbations and Oocyte Penetration1

1992 • 45 citations

Activation of mitogen‐activated protein kinase by the nociceptin receptor expressed in Chinese hamster ovary cells

1997 • 43 citations

Three-Dimensional Microscopy: Image Acquisition and Processing III

1994 • 42 citations

Changes in intracellular calcium of porcine sperm during in vitro incubation with seminal plasma and a capacitating medium

1990 • 34 citations

Microtubule-associated protein-2 in the rat testis: a novel site of expression

1996 • 33 citations

Protein tyrosine kinase, mitogen-activated protein kinase and protein kinase C are involved in the mitogenic signaling of platelet-activating factor (PAF) in HEC-1A cells

1997 • 31 citations

Biochemical characterization of the boar sperm 42 kilodalton protein tyrosine kinase: Its potential for tyrosine as well as serine phosphorylation towards microtubule‐associated protein 2 and histone H 2B

1994 • 22 citations

The Phosphorylation of a Putative Sperm Microtubule-Associated Protein 2 (MAP2) is Uniquely Sensitive to Regulation1

1990 • 18 citations

Expression of the v-Mos oncogene in male meiotic germ cells of transgenic mice results in metaphase arrest.

1995 • 13 citations

Cytosolic and Nuclear Mitogen-Activated Protein Kinases Are Regulated by Distinct Mechanisms

1996 • 12 citations

Achieving confocal-point performance in confocal-line microscopy

1994 • 11 citations

Deleted Work

1955 • 0 citations