Intracellular pH of bovine sperm increases during capacitation

The Physiology of Reproduction

1988 • 3,218 citations

Ionic Channels of Excitable Membranes

1985 • 3,014 citations

Intracellular pH.

1981 • 2,440 citations

Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ

1979 • 2,166 citations

Capacitation of Bovine Sperm by Heparin1

1988 • 1,572 citations

Fertilizing Capacity of Spermatozoa deposited into the Fallopian Tubes

1951 • 1,451 citations

Cytoplasmic pH and free Mg2+ in lymphocytes.

1982 • 1,047 citations

Intracellular pH transients in squid giant axons caused by CO2, NH3, and metabolic inhibitors.

1976 • 913 citations

Observations on the Penetration of the Sperm into the Mammalian Egg

1951 • 907 citations

The ‘Capacitation’ of the Mammalian Sperm

1952 • 690 citations

Metabolic regulation via intracellular pH

1984 • 674 citations

Sperm-egg interactions in the mouse: Sequence of events and induction of the acrosome reaction by a zona pellucida glycoprotein

1983 • 603 citations

Assessment of Fura-2 for measurements of cytosolic free calcium

1990 • 453 citations

Intracellular pH of snail neurones measured with a new pH‐sensitive glass micro‐electrode

1974 • 344 citations

The regulation of the intracellular pH in cells from vertebrates

1988 • 311 citations

Fluorescence ratio imaging microscopy: temporal and spatial measurements of cytoplasmic pH

1987 • 302 citations

Capacitation of Bovine Sperm by Heparin: Inhibitory Effect of Glucose and Role of Intracellular pH1

1989 • 300 citations

Chemical characterization of the component of the jelly coat from sea urchin eggs responsible for induction of the acrosome reaction

1979 • 275 citations

Mechanism of basolateral membrane H+/OH-/HCO-3 transport in the rat proximal convoluted tubule. A sodium-coupled electrogenic process.

1985 • 266 citations

An adhesion-associated agonist from the zona pellucida activates G protein-promoted elevations of internal Ca2+ and pH that mediate mammalian sperm acrosomal exocytosis

1989 • 238 citations

Capacitation of Bovine Spermatozoa by Oviduct Fluid1

1989 • 225 citations

Activation of voltage-dependent calcium channels of mammalian sperm is required for zona pellucida-induced acrosomal exocytosis

1992 • 224 citations

Elevation of the intracellular pH activates respiration and motility of sperm of the sea urchin, Strongylocentrotus purpuratus.

1982 • 215 citations

Changes in internal pH associated with initiation of motility and acrosome reaction of sea urchin sperm

1983 • 214 citations

Metabolism of sea urchin sperm. Interrelationships between intracellular pH, ATPase activity, and mitochondrial respiration.

1983 • 187 citations

Independent elevation of cytosolic [Ca2+] and pH of mammalian sperm by voltage-dependent and pH-sensitive mechanisms.

1987 • 183 citations

Effect of heparin and chondroitin sulfate on the acrosome reaction and fertility of bovine sperm in vitro

1985 • 174 citations

Inhibition of Bovine Spermatozoa by Caudal Epididymal Fluid: II. Interaction of pH and a Quiescence Factor 1

1984 • 172 citations

Chondroitin Sulfate Facilitates an Acrosome Reaction in Bovine Spermatozoa as Evidenced by Light Microscopy, Electron Microscopy and in Vitro Fertilization

1983 • 163 citations

Examination of the intracellular ionic environment and of ionophore action by null point measurements employing the fluorescein chromophore.

1983 • 161 citations

Potassium-dependent increases in cytosolic pH stimulate metabolism and motility of mammalian sperm.

1983 • 149 citations

Membrane potential depolarization and increased intracellular pH accompany the acrosome reaction of sea urchin sperm.

1981 • 146 citations

Digital image processing of intracellular pH in gastric oxyntic and chief cells

1987 • 145 citations

Microspectrofluorometry by digital image processing: measurement of cytoplasmic pH.

1984 • 133 citations

Differences in the Role of Cyclic Adenosine 3′,5′-Monophosphate during Capacitation of Bovine Sperm by Heparin or Oviduct Fluid1

1994 • 126 citations

Calcium requirement and increased association with bovine sperm during capacitation by heparin

1989 • 111 citations

The effects of extracellular sodium on acid release and motility initiation in rat caudal epididymal spermatozoa in vitro

1981 • 106 citations

Thrombin activation of the Na+/H+ exchanger in vascular smooth muscle cells. Evidence for a kinase C-independent pathway which is Ca2+-dependent and pertussis toxin-sensitive.

1987 • 104 citations

Evidence for a role of calmodulin in serum stimulation of Na+ influx in human fibroblasts.

1982 • 96 citations

Na+-independent Cl(-)-HCO-3- exchange in Madin-Darby canine kidney cells. Role in intracellular pH regulation.

1987 • 94 citations

Intracellular pH Regulates Bovine Sperm Motility and Protein Phosphorylation1

1989 • 87 citations

Characterization of an islet-activating protein-sensitive site in mouse sperm that is involved in the zona pellucida-induced acrosome reaction

1988 • 87 citations

THE ROLE OF EXTERNAL SODIUM IN SEA URCHIN FERTILIZATION11This work was supported by a grant from the National Science Foundation to Dr. D. Epel.

1978 • 81 citations

A hydrogen ion flux mediates stimulation of respiratory activity by speract in sea urchin spermatozoa.

1983 • 81 citations

Evidence for plasma membrane impermeability to small ions in acrosome- intact mouse spermatozoa bound to mouse zonae pellucidae, using an aminoacridine fluorescent pH probe: time course of the zona-induced acrosome reaction monitored by both chlortetracycline and pH probe fluorescence

1985 • 80 citations

Metabolism of Sea Urchin Sperm

1949 • 70 citations

Correlation of increased intraacrosomal pH with the hamster sperm acrosome reaction

1983 • 62 citations

Apparent absence of antiport activity in the two-cell mouse embryo

1990 • 59 citations

Bicarbonate/chloride antiport in vero cells: I. Evidence for both sodium‐linked and sodium‐independent exchange

1987 • 56 citations

Heparin-Induced Capacitation but not Intracellular Alkalinization of Bovine Sperm is Inhibited by Rp-Adenosine-3′,5′-Cyclic Monophosphorothioate1

1994 • 55 citations

Na+-H+ and Cl(-)-OH-(HCO3-) exchange in gastric glands

1986 • 54 citations

Effects of Fluoride and Caffeine on the Metabolism and Motility of Ejaculated Bovine Spermatozoa1

1987 • 45 citations

The enhancing effects of anion channel blockers on sperm activation by bicarbonate

1990 • 30 citations

Evidence for a DeltapH-driven Ca2+ uptake in EGTA-treated bovine spermatozoa

1987 • 12 citations

Flow cytometric analysis of lectin binding to bovine sperm during capacitation with heparin or oviduct fluid

1992 • 4 citations