IL-12 attenuates bleomycin-induced pulmonary fibrosis
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References (46)
Idiopathic Pulmonary Fibrosis: Diagnosis and Treatment
2000 • 2,535 citations
A Mechanism for Regulating Pulmonary Inflammation and Fibrosis: The Integrin αvβ6 Binds and Activates Latent TGF β1
1999 • 1,965 citations
THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: Role in Normal and Pathologic Immune Responses
1998 • 1,253 citations
The epidemiology of interstitial lung diseases.
1994 • 912 citations
Induction of TH1 and TH2 responses: a key role for the ‘natural’ immune response?
1992 • 794 citations
international consensus statement
2000 • 794 citations
Inhibition of Angiogenesis In Vivo by Interleukin 12
1995 • 734 citations
A Preliminary Study of Long-Term Treatment with Interferon Gamma-1b and Low-Dose Prednisolone in Patients with Idiopathic Pulmonary Fibrosis
1999 • 585 citations
Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10
1996 • 480 citations
Th1/Th2 Cells
1999 • 475 citations
The pathogenesis of bleomycin-induced pulmonary fibrosis in mice.
1974 • 469 citations
Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis.
1998 • 419 citations
Inhibition of interleukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice.
1996 • 405 citations
Inhibition of interleukin 8 attenuates angiogenesis in bronchogenic carcinoma.
1994 • 373 citations
Interferon-gamma-inducible protein 10 (IP-10) is an angiostatic factor that inhibits human non-small cell lung cancer (NSCLC) tumorigenesis and spontaneous metastases.
1996 • 358 citations
Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis
1999 • 344 citations
Molecular Mechanisms of Antifibrotic Effect of Interferon Gamma in Bleomycin-Mouse Model of Lung Fibrosis: Downregulation of TGF-β and Procollagen I and III Gene Expression
1995 • 306 citations
Immunoregulation by interleukin-12
1996 • 298 citations
Neutralization of the CXC Chemokine, Macrophage Inflammatory Protein-2, Attenuates Bleomycin-Induced Pulmonary Fibrosis
1999 • 243 citations
IFN-gamma-inducible protein-10 attenuates bleomycin-induced pulmonary fibrosis via inhibition of angiogenesis.
1999 • 232 citations
A type 2 (Th2-like) pattern of immune response predominates in the pulmonary interstitium of patients with cryptogenic fibrosing alveolitis (CFA)
1995 • 204 citations
IFN-γ-Inducible Protein-10 Attenuates Bleomycin-Induced Pulmonary Fibrosis Via Inhibition of Angiogenesis
1999 • 196 citations
Modulation by recombinant interleukin 1 of synthesis of types I and III collagens and associated procollagen mRNA levels in cultured human cells.
1987 • 195 citations
Contribution of Natural Killer Cells to Inhibition of Angiogenesis by Interleukin-12
1999 • 192 citations
Lung monocyte chemoattractant protein-1 gene expression in bleomycin-induced pulmonary fibrosis.
1994 • 164 citations
Production and function of murine macrophage inflammatory protein-1 alpha in bleomycin-induced lung injury.
1994 • 161 citations
Contribution of the CXC chemokines IP-10 and Mig to the antitumor effects of IL-12
1998 • 151 citations
Immune interferon suppresses levels of procollagen mRNA and type II collagen synthesis in cultured human articular and costal chondrocytes.
1986 • 151 citations
Morphometric estimates of infiltrative cellular changes during the development of bleomycin-induced pulmonary fibrosis in hamsters.
1983 • 144 citations
Contribution of Natural Killer Cells to Inhibition of Angiogenesis by Interleukin-12
1999 • 136 citations
In vivo levels and in vitro production of interferon-gamma in fibrosing interstitial lung diseases
1992 • 116 citations
Pivotal Role of CCR1-Positive Leukocytes in Bleomycin- Induced Lung Fibrosis in Mice
2000 • 104 citations
Effect of Murine Gamma Interferon on the Cellular Responses to Bleomycin in Mice
1988 • 90 citations
Identification of IFN-γ-Producing Cells in IL-12/IL-18-Treated Mice
1999 • 83 citations
Effects of interferon-gamma on expression of cell surface receptors for collagen and deposition of newly synthesized collagen by cultured human lung fibroblasts.
1989 • 81 citations
Inhibition of type I collagen production by dermal fibroblasts upon contact with activated T cells: Different sensitivity to inhibition between systemic sclerosis and control fibroblasts
1998 • 68 citations
Interleukin-12 Inhibits Angiogenesis Induced by Human Tumor Cell Lines In Vivo
1996 • 67 citations
Inhibition of wound healing in mice by local interferon alpha/beta injection.
1993 • 57 citations
Resistance of TNF/LTα double deficient mice to bleomycin‐induced fibrosis
1997 • 45 citations
SELECTIVE INHIBITION OF COLLAGEN GENE EXPRESSION IN FIBROBLASTS BY AN INTERFERON-gamma TRANSGENE
1999 • 41 citations
Silica enhancement of murine endotoxin sensitivity
1982 • 38 citations
Interleukin‐12 as a target for modulation of the inflammatory response in asthma
1998 • 34 citations
DETERMINATION OF VARIOUS CYTOKINES AND TYPE III PROCOLLAGEN AMINOPEPTIDE LEVELS IN BRONCHOALVEOLARAVAGE FLUID OF THE PATIENTS WITH PULMONARY FIBROSIS: INVERSE CORRELATION BETWEEN TYPE III PROCOLLAGEN AMINOPEPTIDE AND INTERFERON-γ IN PROGRESSIVE PATIENTS
1995 • 33 citations
Effects of interferons on proliferation and collagen synthesis of rat palatal wound fibroblasts
1999 • 20 citations
Diffuse lung disease: a view for the future.
1997 • 13 citations
Bombesin Down Modulates Pulmonary Fibrosis Elicited in Mice by Bleomycin
1995 • 13 citations