Transposition of human immunoglobulin V kappa genes within the same chromosome and the mechanism of their amplification.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Rapid transfer of DNA from agarose gels to nylon membranes

1985 • 1,810 citations

Establishment and characterization of a human prostatic carcinoma cell line (PC-3).

1979 • 1,595 citations

The Origin of Man: A Chromosomal Pictorial Legacy

1982 • 665 citations

Recent progress in understanding mechanisms of mammalian DNA amplification

1989 • 469 citations

Unit-length line-1 transcripts in human teratocarcinoma cells.

1988 • 296 citations

Chromosomal location of human kappa and lambda immunoglobulin light chain constant region genes

1982 • 292 citations

A uniform deleting element mediates the loss of κ genes in human B cells

1985 • 259 citations

Localization of human immunoglobulin kappa light chain variable region genes to the short arm of chromosome 2 by in situ hybridization.

1982 • 242 citations

Double minute chromosomes can be produced from precursors derived from a chromosomal deletion.

1988 • 236 citations

THE EVOLUTION OF MULTIGENE FAMILIES: Human Haptoglobin Genes

1986 • 235 citations

Use of whole cosmid cloned genomic sequences for chromosomal localization by non-radioactive in situ hybridization

1987 • 220 citations

Translocation of an immunoglobulin kappa locus to a region 3' of an unrearranged c-myc oncogene enhances c-myc transcription.

1983 • 204 citations

Revision of consensus sequence of human Alu repeats — a review

1987 • 203 citations

Telomeric repeat from T. thermophila cross hybridizes with human telomeres

1988 • 190 citations

Orphons: Dispersed genetic elements derived from tandem repetitive genes of eucaryotes

1981 • 188 citations

Large inverted duplications are associated with gene amplification

1986 • 147 citations

Effect of chromosomal position on amplification of transfected genes in animal cells

1984 • 140 citations

The multicopy appearance of a large inverted duplication and the sequence at the inversion joint suggest a new model for gene amplification.

1988 • 125 citations

Double Minute Chromosomes Can Be Produced from Precursors Derived from a Chromosomal Deletion

1988 • 112 citations

A hotspot for novel amplification joints in a mosaic of Alu-like repeats and palindromic A + T-rich DNA.

1987 • 111 citations

Immunoglobulin genes of different subgroups are interdigitated within the V_Klocus

1984 • 110 citations

The use of NaOH as transfer solution of DNA onto nylon membrane decreases the hybridization efficiency

1987 • 89 citations

The human C_Kgene segment and the kappa deleting element are closely linked

1986 • 88 citations

Differential amplification, assembly, and relocation of multiple DNA sequences in human neuroblastomas and neuroblastoma cell lines.

1985 • 81 citations

Structure of DNA formed in the first step of CAD gene amplification.

1986 • 78 citations

Structure of Amplified DNA in Different Syrian Hamster Cell Lines Resistant to N-(Phosphonacetyl)-L-Aspartate

1983 • 75 citations

Physical map of the human immunoglobulin K locus and its implications for the mechanisms of V^K–J^Krearrangement

1987 • 72 citations

Dispersed human immunoglobulin κ light-chain genes

1986 • 69 citations

Organization and genesis of dihydrofolate reductase amplicons in the genome of a methotrexate-resistant Chinese hamster ovary cell line.

1988 • 66 citations

Formation of an inverted duplication can be an initial step in gene amplification.

1988 • 65 citations

The kappa-deleting element. Germline and rearranged, duplicated and dispersed forms.

1988 • 61 citations

The human Vκ locus

1987 • 59 citations

DNA amplification-deletion in a spontaneous mutation of the hamsteraprtlocus: structure and sequence of the novel joint

1986 • 58 citations

Mapping of the oncogenes <i>Myc, Sis, </i>and <i>int-1</i> to the distal part of mouse chromosome 15

1987 • 50 citations

Linking of the human immunoglobulin V_KJ_KC_Kregions by chromosomal walking

1987 • 49 citations

Amplification and molecular cloning of murine adenosine deaminase gene sequences.

1983 • 48 citations

Evolution and stability of chromosomal DNA coamplified with the CAD gene.

1989 • 46 citations

Immunoglobulin genes of thexlight chain type from two human lymphoid cell lines are closely related

1984 • 39 citations

The significance of pericentric inversions of chromosome 2

1986 • 38 citations

Experiences with unexpected structural chromosome aberrations in prenatal diagnosis in a danish series

1984 • 32 citations

The Human Immunoglobulin ϰ Locus and Some of its Acrobatics

1990 • 24 citations

Formation of an Inverted Duplication Can Be an Initial Step in Gene Amplification

1988 • 20 citations

Localization, analysis and evolution of transposed human immunoglobulin Vκ genes

1988 • 19 citations

Organization and Genesis of Dihydrofolate Reductase Amplicons in the Genome of a Methotrexate-Resistant Chinese Hamster Ovary Cell Line

1988 • 17 citations

The Z family, a group of transposed human immunoglobulin Vκ genes

1988 • 16 citations

Amplified inverted duplications within and adjacent to heterologous selectable DNAS

1989 • 13 citations

Evolution of a group of transposed human V kappa genes.

1990 • 4 citations

Evolution of a group of transposed human V kappa genes.

1990 • 3 citations