Physical map of the human immunoglobulin K locus and its implications for the mechanisms of V^K–J^Krearrangement

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

1984 • 2,847 citations

Establishment and characterization of a human prostatic carcinoma cell line (PC-3).

1979 • 1,595 citations

Separation of Large DNA Molecules by Contour-Clamped Homogeneous Electric Fields

1986 • 1,525 citations

Separation of chromosomal DNA molecules from yeast by orthogonal-field-alternation gel electrophoresis

1984 • 887 citations

Regulation of Genome Rearrangement Events during Lymphocyte Differentiation

1986 • 422 citations

Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals

1987 • 346 citations

Translocation of an immunoglobulin kappa locus to a region 3' of an unrearranged c-myc oncogene enhances c-myc transcription.

1983 • 204 citations

Evolution of immunoglobulin V genes: Evidence indicating that recently duplicated human Vκ sequences have diverged by gene conversion

1983 • 165 citations

Direct evidence for chromosomal inversion during T-cell receptor β-gene rearrangements

1986 • 151 citations

DNA between variable and joining gene segments of immunoglobulin kappa light chain is frequently retained in cells that rearrange the kappa locus.

1982 • 113 citations

Joining of VK to JK gene segments in a retroviral vector introduced into lymphoid cells

1984 • 110 citations

Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene

1985 • 109 citations

Double recombination of a single immunoglobulin kappa-chain allele: implications for the mechanism of rearrangement.

1985 • 89 citations

Recombined flanks of the variable and joining segments of immunoglobulin genes.

1982 • 83 citations

A large section of the gene locus encoding human immunoglobulin variable regions of the Kappa type is duplicated

1985 • 80 citations

A rearranged DNA sequence possibly related to the translocation of immunoglobulin gene segments

1980 • 75 citations

Dispersed human immunoglobulin κ light-chain genes

1986 • 69 citations

Contribution of human VκII germ-line genes to light-chain diversity

1984 • 65 citations

Gene for the human T cell differentiation antigen Leu-2/T8 is closely linked to the kappa light chain locus on chromosome 2.

1985 • 60 citations

The human Vκ locus

1987 • 59 citations

N segment insertion and region-directed somatic hypermutation in a Kappa gene of a t(2;8) chromosomal translocation

1987 • 45 citations

Immunoglobulin genes of thexlight chain type from two human lymphoid cell lines are closely related

1984 • 39 citations

Aberrant recombination events in B cell lines derived from ax-deficient human

1985 • 37 citations

Reciprocal recombination products of V_K-J_Kjoining reactions in human lymphoid cell lines

1987 • 34 citations

Detection of a unique human V×IV gennline gene by a cloned cDNA probe

1985 • 25 citations