Localization of platelet-derived growth factor (PDGF) in CHO cells transfected with PDGF A- or B-chain cDNA: Retention of PDGF-BB in the endoplasmic reticulum and Golgi complex

PERIODATE-LYSINE-PARAFORMALDEHYDE FIXATIVE A NEW FIXATIVE FOR IMMUNOELECTRON MICROSCOPY

1974 • 3,882 citations

The biology of platelet-derived growth factor

1986 • 2,036 citations

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1983 • 1,657 citations

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1983 • 1,550 citations

The Golgi apparatus (complex)-(1954-1981)-from artifact to center stage.

1981 • 990 citations

BIOSYNTHETIC PROTEIN TRANSPORT AND SORTING BY THE ENDOPLASMIC RETICULUM AND GOLGI

1987 • 985 citations

Control of Protein Exit from the Endoplasmic Reticulum

1989 • 794 citations

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1986 • 786 citations

Two Classes of PDGF Receptor Eecognize Different Isoforms of PDGF

1988 • 603 citations

Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types.

1988 • 514 citations

Regulation of Protein Export From the Endoplasmic Reticulum

1988 • 421 citations

Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor

1983 • 352 citations

cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules.

1988 • 338 citations

Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles

1987 • 335 citations

A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain.

1988 • 317 citations

Microtubules and the organization of the Golgi complex

1985 • 311 citations

Autocrine Stimulation of Intracellular PDGF Receptors in v- sis -Transformed Cells

1988 • 267 citations

Chromatin binding of epidermal growth factor, nerve growth factor, and platelet-derived growth factor in cells bearing the appropriate surface receptors.

1986 • 193 citations

Comparison of Biological Properties and Transforming Potential of Human PDGF-A and PDGF-B Chains

1988 • 178 citations

Platelet-derived growth factor: Three isoforms and two receptor types

1989 • 178 citations

Role of microtubules in the organisation of the Golgi apparatus

1990 • 171 citations

Transformation by v- sis Occurs by an Internal Autoactivation Mechanism

1989 • 171 citations

Rapid turnover of the platelet-derived growth factor receptor in sis-transformed cells and reversal by suramin. Implications for the mechanism of autocrine transformation.

1988 • 147 citations

The v-sis/PDGF-2 transforming gene product localizes to cell membranes but is not a secretory protein.

1985 • 143 citations

Expression of Three Recombinant Homodimeric Isoforms of PDGF inSaccharomyces cerevisiae: Evidence for Difference in Receptor Binding and Functional Activities

1989 • 126 citations

Growth factors as transforming proteins

1989 • 122 citations

Chapter 10 Low Temperature-Induced Transport Blocks as Tools to Manipulate Membrane Traffic

1989 • 116 citations

Autocrine mechanism for v-sis transformation requires cell surface localization of internally activated growth factor receptors.

1989 • 112 citations

Chapter 25 Immunoperoxidase Methods for the Localization of Antigens in Cultured Cells and Tissue Sections by Electron Microscopy

1989 • 101 citations

Synthesis and assembly of a functionally active recombinant platelet-derived growth factor AB heterodimer.

1988 • 96 citations

Sorting and traffic in the central vacuolar system

1989 • 95 citations

Platelet‐derived growth factor: Morphologic and biochemical studies of binding, internalization, and degradation

1984 • 88 citations

Surface binding and internalization of platelet-derived growth factor in human fibroblasts.

1983 • 87 citations

Identification of a signal for nuclear targeting in platelet-derived-growth-factor-related molecules.

1987 • 85 citations

Platelet-derived growth factor agonist activity of a secreted form of the v-sis oncogene product.

1985 • 72 citations

Expression of recombinant platelet-derived growth factor A- and B-chain homodimers in rat-1 cells and human fibroblasts reveals differences in protein processing and autocrine effects.

1988 • 71 citations

Autocrine stimulation by the v-sis gene product requires a ligand-receptor interaction at the cell surface.

1988 • 64 citations

Ultrastructural localization of a platelet-derived growth factor/v-sis-related protein(s) in cytoplasm and nucleus of simian sarcoma virus-transformed cells.

1987 • 63 citations

Platelet-derived Growth Factor Receptor Inducibility Is Acquired Immediately after Translation and Does Not Require Glycosylation

1989 • 29 citations

Relationship between Golgi Architecture and Glycoprotein Biosynthesis and Transport in Chinese Hamster Ovary Cells

1989 • 28 citations

Purification of a growth factor related to platelet-derived growth factor and a type β transforming growth factor secreted by mouse neuroblastoma cells. A general strategy for the purification of basic polypeptide growth factors

1989 • 18 citations

Ultrastructural localization of platelet-derived growth factor and related factors in normal and transformed cells

1988 • 16 citations

Platelet-derived growth factor labeled to colloidal gold for use as a mitogenic receptor probe.

1984 • 11 citations