Relationship between Golgi Architecture and Glycoprotein Biosynthesis and Transport in Chinese Hamster Ovary Cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

Intracellular Aspects of the Process of Protein Synthesis

1975 • 3,560 citations

A simple and rapid method for the permethylation of carbohydrates

1984 • 3,459 citations

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

1985 • 1,930 citations

The trans Golgi Network: Sorting at the Exit Site of the Golgi Complex

1986 • 1,175 citations

Pathways of Protein Secretion in Eukaryotes

1985 • 1,050 citations

Constitutive and Regulated Secretion of Proteins

1987 • 1,021 citations

The Golgi apparatus (complex)-(1954-1981)-from artifact to center stage.

1981 • 990 citations

BIOSYNTHETIC PROTEIN TRANSPORT AND SORTING BY THE ENDOPLASMIC RETICULUM AND GOLGI

1987 • 985 citations

Reconstitution of the transport of protein between successive compartments of the golgi measured by the coupled incorporation of N-acetylglucosamine

1984 • 689 citations

Microtubules and the endoplasmic reticulum are highly interdependent structures.

1986 • 633 citations

Progress in Unraveling Pathways of Golgi Traffic

1985 • 615 citations

MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties.

1987 • 563 citations

Retrograde transport by the microtubule-associated protein MAP 1C

1987 • 547 citations

Fractionation of asparagine-linked oligosaccharides by serial lectin-Agarose affinity chromatography. A rapid, sensitive, and specific technique.

1982 • 508 citations

Translocation and clustering of endosomes and lysosomes depends on microtubules.

1987 • 498 citations

Carbohydrate structure of erythropoietin expressed in Chinese hamster ovary cells by a human erythropoietin cDNA.

1987 • 485 citations

The hydrolysis of chitin by concentrated hydrochloric acid, and the preparation of low-molecular-weight substrate for lysozyme

1964 • 474 citations

Dynamic behavior of endoplasmic reticulum in living cells

1988 • 471 citations

Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro

1985 • 463 citations

Compartmental organization of the golgi stack

1985 • 442 citations

Gliding movement of and bidirectional transport along single native microtubules from squid axoplasm: evidence for an active role of microtubules in cytoplasmic transport.

1985 • 440 citations

Antibodies to the Golgi complex and the rough endoplasmic reticulum.

1982 • 418 citations

Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound.

1982 • 403 citations

10-nm filaments are induced to collapse in living cells microinjected with monoclonal and polyclonal antibodies against tubulin.

1984 • 388 citations

Localization of endoplasmic reticulum in living and glutaraldehyde-fixed cells with fluorescent dyes

1984 • 384 citations

The microtubule-dependent formation of a tubulovesicular network with characteristics of the ER from cultured cell extracts

1988 • 359 citations

Intracellular Transport Using Microtubule-Based Motors

1987 • 356 citations

A Vital Stain for the Golgi Apparatus

1985 • 344 citations

Nucleoside transport in mammalian cells. Inhibition by colchicine

1972 • 323 citations

Microtubules and the organization of the Golgi complex

1985 • 311 citations

Comparative study of the asparagine-linked sugar chains of human erythropoietins purified from urine and the culture medium of recombinant Chinese hamster ovary cells.

1988 • 304 citations

Associations of elements of the Golgi apparatus with microtubules.

1984 • 291 citations

Subcellular organization of glycosylation in mammalian cells

1987 • 271 citations

Tubular lysosome morphology and distribution within macrophages depend on the integrity of cytoplasmic microtubules.

1987 • 270 citations

Polarized Intracellular Particle Transport: Saltatory Movements and Cytoplasmic Streaming

1972 • 267 citations

The distribution of repeating [Gal beta 1,4GlcNAc beta 1,3] sequences in asparagine-linked oligosaccharides of the mouse lymphoma cell lines BW5147 and PHAR 2.1.

1984 • 246 citations

Structural studies of phosphorylated high mannose-type oligosaccharides.

1980 • 236 citations

A microtubule-binding protein associated with membranes of the Golgi apparatus.

1986 • 234 citations

Propulsion of organelles isolated from Acanthamoeba along actin filaments by myosin-I

1986 • 227 citations

[18] Lectin affinity chromatography of glycopeptides

1987 • 215 citations

A mouse lymphoma cell line resistant to the leukoagglutinating lectin from Phaseolus vulgaris is deficient in UDP-GlcNAc: alpha-D-mannoside beta 1,6 N-acetylglucosaminyltransferase.

1982 • 211 citations

Microtubule-acting drugs lead to the nonpolarized delivery of the influenza hemagglutinin to the cell surface of polarized Madin-Darby canine kidney cells.

1987 • 210 citations

Effect of microtubule assembly status on the intracellular processing and surface expression of an integral protein of the plasma membrane.

1984 • 209 citations

Membrane insertion at the leading edge of motile fibroblasts.

1983 • 192 citations

A mitotic form of the Golgi apparatus in HeLa cells

1987 • 183 citations

Nocodazole, a microtubule-active drug, interferes with apical protein delivery in cultured intestinal epithelial cells (Caco-2).

1989 • 176 citations

Intracellular segregation of asialoglycoproteins and their receptor: a prelysosomal event subsequent to dissociation of the ligand-receptor complex.

1984 • 168 citations

A time-lapse video image intensification analysis of cytoplasmic organelle movements during endosome translocation.

1984 • 158 citations

Microtubules and actin filaments are not critically involved in the biogenesis of epithelial cell surface polarity.

1986 • 142 citations

Relationship of the terminal sequences to the length of poly-N-acetyllactosamine chains in asparagine-linked oligosaccharides from the mouse lymphoma cell line BW5147. Immobilized tomato lectin interacts with high affinity with glycopeptides containing long poly-N-acetyllactosamine chains.

1987 • 140 citations

Role of microtubules in the distribution of the Golgi apparatus: effect of taxol and microinjected anti-alpha-tubulin antibodies.

1983 • 129 citations

Protein glycosylation in the endoplasmic reticulum: current topological issues

1987 • 107 citations

Cytoplasmic transport in keratocytes: Direct visualization of particle translocation along microtubules

1983 • 106 citations

Structure of an unusual complex-type oligosaccharide isolated from Chinese hamster ovary cells

1980 • 98 citations

Synthesis of membrane glycoproteins in rat small-intestinal villus cells. Effect of colchicine on the redistribution of <scp>l</scp>-[1,5,6-3H]fucose-labelled membrane glycoproteins among Golgi, lateral basal and microvillus membranes

1979 • 93 citations

Asparagine-linked oligosaccharides containing poly-N-acetyllactosamine chains are preferentially bound by immobilized calf heart agglutinin.

1988 • 90 citations

Motility in the siphonous green alga Bryopsis. II. Chloroplast movement requires organized arrays of both microtubules and actin filaments.

1986 • 90 citations

Sulfated N-linked oligosaccharides in mammalian cells. I. Complex-type chains with sialic acids and O-sulfate esters.

1988 • 90 citations

Identification of a secretory granule-binding protein as caldesmon

1986 • 89 citations

Human interleukin 1 beta is not secreted from hamster fibroblasts when expressed constitutively from a transfected cDNA.

1988 • 87 citations

Role of Microtubules in Low Density Lipoprotein Processing by Cultured Cells

1979 • 85 citations

Microtubules and beta cell function: effect of colchicine on microtubules and insulin secretion in vitro by mouse beta cells.

1982 • 84 citations

Analysis of the role of microtubules and actin in erythrophore intracellular motility.

1983 • 82 citations

Dynamics of the endoplasmic reticulum in living onion epidermal cells in relation to microtubules, microfilaments, and intracellular particle movement

1988 • 80 citations

N-andO-alkylation of glycoconjugates and polysaccharides by solid base in dimethyl sulphoxide/alkyl lodide

1987 • 72 citations

The in vivo effect of colchicine on the addition of galactose and sialic acid to rat hepatic serum glycoproteins.

1976 • 63 citations

Microtubules and protein secretion in rat lacrimal glands: localization of short-term effects of colchicine on the secretory process.

1982 • 63 citations

Chapter 6 Separation and Analysis of Glycoprotein Oligosaccharides

1989 • 59 citations

Microtubule polarity confers direction to pigment transport in chromatophores.

1986 • 59 citations

Role of microtubules in the synthesis, conversion, and release of (pro)insulin. A biochemical and radioautographic study in rat islets.

1979 • 58 citations

The effect of colchicine on the intracellular transport of 3H-fucose-labelled glycoproteins in the absorptive cells of cultured human small-intestinal tissue

1981 • 55 citations

Effect of various hepatic membrane fractions on microtubule assembly-with special emphasis on the role of membrane phospholipids.

1981 • 51 citations

Yeast vacuoles fragment when microtubules are disrupted.

1988 • 49 citations

Structure of sulfatides biosynthesized in vitro

1971 • 48 citations

Influence of colchicine and vinblastine on the intracellular migration of secretory and membrane glycoproteins: III. Inhibition of intracellular migration of membrane glycoproteins in rat intestinal columnar cells and hepatocytes as visualized by light and electron‐microscope radioautography after ³h‐fucose injection

1984 • 45 citations

Chapter 11 Three-Dimensional Structure of the Golgi Apparatus

1981 • 44 citations

Binding of [3H]cytochalasin B and [3H]colchicine to isolated liver plasma membranes

1977 • 38 citations

An effect of colchicine on galactosyl- and sialyltransferases of rat liver golgi membranes

1981 • 34 citations

Cells injected with guanosine 5'-[alpha, beta-methylene]triphosphate, an alpha, beta-nonhydrolyzable analog of GTP, show anomalous patterns of tubulin polymerization affecting cell translocation, intracellular movement, and the organization of Golgi elements.

1983 • 27 citations

Immunocytochemical localization of alkaline phosphatase in absorptive cells of rat small intestine after colchicine treatment

1987 • 26 citations

Taxol, a potent promoter of microtubule assembly, inhibits secretion of plasma proteins in cultured rat hepatocytes

1982 • 25 citations

Chapter 16 Effects of Antimitotic Agents on Ultrastructure and Intracellular Transport of Protein in Pancreatic Acini

1981 • 18 citations

Influence of colchicine and vinblastine on the intracellular migration of secretory and membrane glycoproteins: I. Inhibition of glycoprotein migration in various rat cell types as shown by light microscope radioautography after injection of ³H‐fucose

1984 • 17 citations

Chapter 15 The Effect of Colchicine on the Synthesis and Secretion of Rat Serum Albumin

1981 • 15 citations

Factors that influence the uptake of β-hemosaminidase a by rat peritoneal macrophages

1980 • 14 citations

Chapter 14 Actin Filaments and Secretion: The Macrophage Model

1981 • 12 citations

Influence of colchicine and vinblastine on the intracellular migration of secretory and membrane glycoproteins: II. Inhibition of secretion of thyroglobulin in rat thyroid follicular cells as visualized by radioautography after ³H‐fucose injection

1984 • 12 citations