Influence of caveolin-1 on cellular cholesterol efflux mediated by high-density lipoproteins

High density lipoprotein as a protective factor against coronary heart disease

1977 • 5,019 citations

The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor

1997 • 3,702 citations

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

1998 • 3,026 citations

Caveolin, a protein component of caveolae membrane coats

1992 • 2,230 citations

THE CAVEOLAE MEMBRANE SYSTEM

1998 • 1,947 citations

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

1999 • 1,708 citations

High-Density Lipoprotein — The Clinical Implications of Recent Studies

1989 • 1,565 citations

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

1999 • 1,527 citations

Molecular physiology of reverse cholesterol transport.

1995 • 1,452 citations

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

1999 • 1,441 citations

THE TROMSØHEART-STUDY

1977 • 1,212 citations

Caveolins, Liquid-Ordered Domains, and Signal Transduction

1999 • 1,016 citations

Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease.

1994 • 912 citations

VIP21/caveolin is a cholesterol-binding protein.

1995 • 892 citations

Molecular Cloning of Caveolin-3, a Novel Member of the Caveolin Gene Family Expressed Predominantly in Muscle

1996 • 737 citations

The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

1999 • 732 citations

Expression of Caveolin-3 in Skeletal, Cardiac, and Smooth Muscle Cells

1996 • 692 citations

Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis

1994 • 646 citations

Identification, sequence, and expression of caveolin-2 defines a caveolin gene family.

1996 • 566 citations

Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

1999 • 562 citations

Oligomeric structure of caveolin: implications for caveolae membrane organization.

1995 • 547 citations

A New Function for the LDL Receptor: Transcytosis of LDL across the Blood–Brain Barrier

1997 • 531 citations

Cell-type and Tissue-specific Expression of Caveolin-2

1997 • 524 citations

Reduction of caveolin and caveolae in oncogenically transformed cells.

1995 • 505 citations

Cell cholesterol efflux: integration of old and new observations provides new insights

1999 • 502 citations

The Tromsø Heart Study

1983 • 500 citations

[6] Sequential flotation ultracentrifugation

1986 • 497 citations

A Role for Caveolin in Transport of Cholesterol from Endoplasmic Reticulum to Plasma Membrane

1996 • 496 citations

Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

1998 • 473 citations

Cellular Cholesterol Efflux Mediated by Cyclodextrins

1996 • 456 citations

Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation.

1994 • 425 citations

Recombinant Expression of Caveolin-1 in Oncogenically Transformed Cells Abrogates Anchorage-independent Growth

1997 • 377 citations

Cholesterol Depletion of Caveolae Causes Hyperactivation of Extracellular Signal-related Kinase (ERK)

1998 • 375 citations

Murine SR-BI, a High Density Lipoprotein Receptor That Mediates Selective Lipid Uptake, Is N-Glycosylated and Fatty Acylated and Colocalizes with Plasma Membrane Caveolae

1997 • 375 citations

Caveolin‐mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo

1998 • 371 citations

Gp60 Activation Mediates Albumin Transcytosis in Endothelial Cells by Tyrosine Kinase-dependent Pathway

1997 • 371 citations

Sequence and expression of caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in Rous sarcoma virus-transformed fibroblasts.

1992 • 369 citations

Tyrosine Phosphorylation of a 22-kDa Protein Is Correlated with Transformation by Rous Sarcoma Virus

1989 • 363 citations

Caveolin Isoforms Differ in Their N-terminal Protein Sequence and Subcellular Distribution. IDENTIFICATION AND EPITOPE MAPPING OF AN ISOFORM-SPECIFIC MONOCLONAL ANTIBODY PROBE

1995 • 362 citations

Apolipoprotein-mediated removal of cellular cholesterol and phospholipids

1996 • 346 citations

Lipids, risk factors and ischaemic heart disease

1996 • 323 citations

High Density Lipoprotein Prevents Oxidized Low Density Lipoprotein-induced Inhibition of Endothelial Nitric-oxide Synthase Localization and Activation in Caveolae

2000 • 308 citations

Regulation of caveolin and caveolae by cholesterol in MDCK cells

1998 • 307 citations

The Correlation of ATP-binding Cassette 1 mRNA Levels with Cholesterol Efflux from Various Cell Lines

2000 • 299 citations

Intracellular cholesterol transport

1997 • 295 citations

Apolipoprotein A-I: structure–function relationships

2000 • 293 citations

Plasma membrane caveolae mediate the efflux of cellular free cholesterol

1995 • 273 citations

Apolipoproteins, membrane cholesterol domains, and the regulation of cholesterol efflux.

1992 • 269 citations

Human ATP-binding cassette transporter 1 (ABC1): Genomic organization and identification of the genetic defect in the original Tangier disease kindred

1999 • 267 citations

Protein kinase C as a mediator of high density lipoprotein receptor-dependent efflux of intracellular cholesterol

1991 • 259 citations

Two sterol regulatory element-like sequences mediate up-regulation of caveolin gene transcription in response to low density lipoprotein free cholesterol

1997 • 256 citations

Caveolin Interaction with Protein Kinase C

1997 • 254 citations

Caveolin mRNA levels are up-regulated by free cholesterol and down-regulated by oxysterols in fibroblast monolayers

1997 • 241 citations

M‐caveolin, a muscle‐specific caveolin‐related protein

1996 • 238 citations

A DNA cassette containing a trimerized SV40 polyadenylation signal which efficiently blocks spurious plasmid-initiated transcription.

1989 • 215 citations

Reciprocal Regulation of Neu Tyrosine Kinase Activity and Caveolin-1 Protein Expression in Vitro and in Vivo

1998 • 215 citations

Determinants of Change in Total Cholesterol and HDL-C With Age: The Framingham Study

1994 • 215 citations

Rapid fluorometric assay of LDL receptor activity by DiI-labeled LDL.

1993 • 208 citations

Thyroid Hormone Regulates the Mouse Thyrotropin β-Subunit Gene Promoter in Transfected Primary Thyrotropes

1989 • 203 citations

Cellular cholesterol efflux

2001 • 193 citations

M‐caveolin, a muscle‐specific caveolin‐related protein

1995 • 188 citations

Regulation of cAMP-mediated Signal Transduction via Interaction of Caveolins with the Catalytic Subunit of Protein Kinase A

1999 • 178 citations

p42/44 MAP Kinase-dependent and -independent Signaling Pathways Regulate Caveolin-1 Gene Expression

1999 • 167 citations

Baculovirus-based Expression of Mammalian Caveolin in Sf21 Insect Cells

1996 • 134 citations

Efflux of lipid from fibroblasts to apolipoproteins: dependence on elevated levels of cellular unesterified cholesterol.

1992 • 129 citations

Efflux of Cholesterol from Different Cellular Pools

2000 • 127 citations

Phospholipid transfer protein enhances removal of cellular cholesterol and phospholipids by high-density lipoprotein apolipoproteins

1999 • 109 citations

Intracellular Transport of Low Density Lipoprotein Derived Free Cholesterol Begins at Clathrin-Coated Pits and Terminates at Cell Surface Caveolae

1996 • 98 citations

Induction of cellular cholesterol efflux to lipid-free apolipoprotein A-I by cAMP

1999 • 94 citations

Cellular cholesterol efflux. Role of cell membrane kinetic pools and interaction with apolipoproteins AI, AII, and Cs.

1992 • 92 citations

Removal of cellular cholesterol by pre-β-HDL involves plasma membrane microsolubilization

1998 • 89 citations

c-Jun represses transcription of the human chorionic gonadotropin alpha and beta genes through distinct types of CREs.

1994 • 82 citations

Triton X-100-resistant membrane complexes from cultured kidney epithelial cells contain the Src family protein tyrosine kinase p62yes.

1994 • 80 citations

Proatherosclerotic events: pathobiochemical changes occurring in the arterial wall before monocyte migration

1993 • 75 citations

Identification of cAMP analogue inducible genes in RAW264 macrophages

2000 • 66 citations

Effect of cholesterol on apolipoprotein A-I binding to lipid bilayers and emulsions

1997 • 60 citations

The primary sequence of murine caveolin reveals a conserved consensus site for phosphorylation by protein kinase C

1994 • 53 citations

Cyclic AMP stimulates efflux of intracellular sterol from cholesterol-loaded cells.

1993 • 52 citations

Caveolins in cholesterol trafficking and signal transduction: implications for human disease

2000 • 49 citations

High Density Lipoproteins Stimulate Mitogen-Activated Protein Kinases in Human Skin Fibroblasts

1997 • 44 citations

Phospholipase D2: functional interaction with caveolin in low‐density membrane microdomains

2000 • 42 citations

Caveolae and human disease: functional roles in transcytosis, potocytosis, signalling and cell polarity

1995 • 37 citations

Genomic organization and transcriptional analysis of the human genes coding for caveolin-1 and caveolin-2

2000 • 34 citations

Importance of Central α-Helices of Human Apolipoprotein A-I in the Maturation of High-Density Lipoproteins

1998 • 32 citations

The Role of Cholesteryl Ester Transfer Protein and Phospholipid Transfer Protein in the Remodeling of Plasma High-Density Lipoproteins

1997 • 22 citations