Therapeutic Relevance of CD34 Cell Dose in Blood Cell Transplantation for Cancer Therapy

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1970 • 2,595 citations

Autologous Bone Marrow Transplantation as Compared with Salvage Chemotherapy in Relapses of Chemotherapy-Sensitive Non-Hodgkin's Lymphoma

1995 • 2,428 citations

A PROSPECTIVE, RANDOMIZED TRIAL OF AUTOLOGOUS BONE MARROW TRANSPLANTATION AND CHEMOTHERAPY IN MULTIPLE MYELOMA

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STROMAL CELLS RESPONSIBLE FOR TRANSFERRING THE MICROENVIRONMENT OF THE HEMOPOIETIC TISSUES

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The ISHAGE Guidelines for CD34+ Cell Determination by Flow Cytometry

1996 • 1,249 citations

Treatment of High-Risk Acute Leukemia with T-Cell–Depleted Stem Cells from Related Donors with One Fully Mismatched HLA Haplotype

1998 • 1,200 citations

Stromal Stem Cells: Marrow‐Derived Osteogenic Precursors

2007 • 1,181 citations

Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species

1997 • 1,116 citations

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1989 • 1,097 citations

Regulatory Mechanisms in Stem Cell Biology

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Autologous or Allogeneic Bone Marrow Transplantation Compared with Intensive Chemotherapy in Acute Myelogenous Leukemia

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1980 • 837 citations

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1996 • 690 citations

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1995 • 659 citations

The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursors

1994 • 644 citations

A newly discovered class of human hematopoietic cells with SCID-repopulating activity

1998 • 640 citations

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1987 • 636 citations

Randomised trial of filgrastim-mobilised peripheral blood progenitor cell transplantation versus autologous bone-marrow transplantation in lymphoma patients

1996 • 633 citations

Binding of L-Selectin to the Vascular Sialomucin CD34

1993 • 629 citations

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1995 • 616 citations

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1980 • 597 citations

Allogeneic blood stem cell transplantation for refractory leukemia and lymphoma: potential advantage of blood over marrow allografts [see comments]

1995 • 557 citations

Circulation of CD34+ hematopoietic stem cells in the peripheral blood of high-dose cyclophosphamide-treated patients: enhancement by intravenous recombinant human granulocyte-macrophage colony-stimulating factor

1989 • 549 citations

Flow cytometry for clinical estimation of circulating hematopoietic progenitors for autologous transplantation in cancer patients

1991 • 519 citations

Primary transplantation of allogeneic peripheral blood progenitor cells mobilized by filgrastim (granulocyte colony-stimulating factor) [see comments]

1995 • 508 citations

High-Dose Chemotherapy and Autologous Bone Marrow Transplantation Compared with MACOP-B in Aggressive B-Cell Lymphoma

1997 • 494 citations

Patient characteristics associated with successful mobilizing and autografting of peripheral blood progenitor cells in malignant lymphoma

1994 • 484 citations

Hematopoietic regulators: redundancy or subtlety?

1993 • 473 citations

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1996 • 393 citations

Improved immune reconstitution after allotransplantation of peripheral blood stem cells instead of bone marrow

1996 • 374 citations

Allogeneic peripheral blood stem cell transplantation in patients with advanced hematologic malignancies: a retrospective comparison with marrow transplantation

1996 • 370 citations

Adipocytic cells cultured from marrow have osteogenic potential

1991 • 363 citations

Human bone marrow CD34- cells engraft in vivo and undergo multilineage expression that includes giving rise to CD34+ cells.

1998 • 346 citations

High-Dose Therapy and Autologous Hematopoietic Progenitor Cell Transplantation for Recurrent or Refractory Hodgkin's Disease: Analysis of the Stanford University Results and Prognostic Indices

1997 • 336 citations

Allogeneic Peripheral Blood Stem Cell Transplantation May Be Associated With a High Risk of Chronic Graft-Versus-Host Disease

1997 • 329 citations

Harvesting and enrichment of hematopoietic progenitor cells mobilized into the peripheral blood of normal donors by granulocyte-macrophage colony-stimulating factor (GM-CSF) or G-CSF: potential role in allogeneic marrow transplantation

1995 • 304 citations

Allogeneic bone marrow transplantation vs filgrastim-mobilised peripheral blood progenitor cell transplantation in patients with early leukaemia: first results of a randomised multicentre trial of the European Group for Blood and Marrow Transplantation

1998 • 276 citations

Circulating autologous stem cells collected in very early remission from acute non‐lymphoblastic leukaemia produce prompt but incomplete haemopoietic reconstitution after high dose melphalan or supralethal chemoradiotherapy

1985 • 238 citations

Accelerated telomere shortening in young recipients of allogeneic bone-marrow transplants

1998 • 236 citations

Peripheral Blood Stem Cell and Bone Marrow Transplantation for Solid Tumors and Lymphomas: Hematologic Recovery and Costs: A Randomized, Controlled Trial

1997 • 234 citations

Successful autologous transplantation of blood stem cells mobilized with recombinant human granulocyte-macrophage colony-stimulating factor.

1990 • 230 citations

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High levels of circulating haemopoietic stem cells in very early remission from acute non‐lymphoblastic leukaemia and their collection and cryopreservation

1984 • 206 citations

Clonal analysis in vitro of osteogenic differentiation of marrow CFU-F

1987 • 206 citations

Flow cytometric enumeration of CD34+ hematopoietic stem and progenitor cells

1998 • 203 citations

A comparative study of the phenotype and proliferative capacity of peripheral blood (PB) CD34+ cells mobilized by four different protocols and those of steady-phase PB and bone marrow CD34+ cells

1994 • 192 citations

Efficacy, toxicity, and applicability of high-dose sequential chemotherapy as adjuvant treatment in operable breast cancer with 10 or more involved axillary nodes: five-year results.

1997 • 190 citations

High CD34+ Cell Counts Decrease Hematologic Toxicity of Autologous Peripheral Blood Progenitor Cell Transplantation

1998 • 186 citations

Bone marrow transplantation across HLA barriers by increasing the number of transplanted cells

1995 • 171 citations

The Recovery of Lethally Irradiated Dogs Given Infusions of Autologous Leukocytes Preserved at -80 C

1964 • 166 citations

Differential Maintenance of Primitive Human SCID-Repopulating Cells, Clonogenic Progenitors, and Long-Term Culture-Initiating Cells After Incubation on Human Bone Marrow Stromal Cells

1997 • 159 citations

Mobilization of hematopoietic stem and progenitor cell subpopulations from the marrow to the blood of mice following cyclophosphamide and/or granulocyte colony-stimulating factor

1993 • 151 citations

Peripheral Blood Progenitor Cell Mobilization Using Stem Cell Factor in Combination With Filgrastim in Breast Cancer Patients

1997 • 150 citations

Progenitor-cell mobilization after low-dose cyclophosphamide and granulocyte colony-stimulating factor: an analysis of progenitor-cell quantity and quality and factors predicting for these parameters in 101 pretreated patients with malignant lymphoma.

1997 • 147 citations

Subsets of CD34+ cells and rapid hematopoietic recovery after peripheral-blood stem-cell transplantation.

1995 • 143 citations

High-dose therapy followed by autologous peripheral-blood stem-cell transplantation for patients with Hodgkin's disease and non-Hodgkin's lymphoma using unprimed and granulocyte colony-stimulating factor-mobilized peripheral-blood stem cells.

1994 • 140 citations

Comparison of peripheral blood progenitor cell mobilization in patients with multiple myeloma: high-dose cyclophosphamide plus GM-CSF vs G-CSF alone

1997 • 135 citations

Relationship of CD34+ cell dose to early and late hematopoiesis following autologous peripheral blood stem cell transplantation

1997 • 125 citations

Flt-3 Ligand Synergizes With Granulocyte Colony-Stimulating Factor to Increase Neutrophil Numbers and to Mobilize Peripheral Blood Stem Cells With Long-Term Repopulating Potential

1997 • 122 citations

Rapid and complete hemopoietic reconstitution following combined transplantation of autologous blood and bone marrow cells. A changing role for high dose chemo‐radiotherapy?

1989 • 117 citations

Mobilization of peripheral blood progenitor cells with high-dose cyclophosphamide (4 or 7 g/m2) and granulocyte colony-stimulating factor in patients with multiple myeloma.

1996 • 113 citations

Early lympho-hemopoietic recovery after autografting using peripheral blood stem cells in acute non-lymphoblastic leukemia.

1988 • 111 citations

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1979 • 110 citations

Antigenic Analysis of Hematopoiesis: A Review

1993 • 109 citations

High-dose therapy and peripheral blood progenitor cell transplantation: effects of recombinant human granulocyte-macrophage colony-stimulating factor on the autograft

1994 • 108 citations

Potential Adhesion Mechanisms for Localisation of Haemopoietic Progenitors to Bone Marrow Stroma

1994 • 108 citations

Peripheral Blood Stem Cell Mobilization by Chemotherapy With and Without Recombinant Human Granulocyte Colony-Stimulating Factor

1992 • 105 citations

Result of attempted hematopoietic reconstitution using isologous, peripheral blood mononuclear cells: a case report

1980 • 105 citations

The Biology and Application of Human Bone Marrow Stromal Cell Precursors

1996 • 102 citations

Methodology of long-term culture of human hemopoietic cells

1991 • 91 citations

CD34-positive cells: biology and clinical relevance.

1995 • 87 citations

Marrow Engraftment by Allogeneic Leukocytes in Lethally Irradiated Dogs

1967 • 85 citations

Effect of chemotherapy for acute myelogenous leukemia on hematopoietic and fibroblast marrow progenitors

1997 • 83 citations

Long-Term Follow-Up of High-Risk Allogeneic Peripheral-Blood Stem-Cell Transplant Recipients: Graft-Versus-Host Disease and Transplant-Related Mortality

1999 • 83 citations

Blood and marrow transplantation activity in Europe 1996

1998 • 78 citations

Autografting for patients with chronic myeloid leukaemia in chronic phase: peripheral blood stem cells may have a finite capacity for maintaining haemopoiesis

1989 • 76 citations

Bone marrow reconstitution after high-dose chemotherapy and autologous peripheral blood progenitor cell transplantation: Effect of graft size

1994 • 75 citations

Bone marrow stromal function from patients after bone marrow transplantation.

1995 • 71 citations

Effect of different chemotherapy regimens on peripheral-blood stem-cell collections in patients with breast cancer receiving granulocyte colony-stimulating factor.

1997 • 69 citations

High-dose sequential chemo-radiotherapy with peripheral blood progenitor cell support for relapsed or refractory Hodgkin's disease — A 6-year update

1993 • 67 citations

CD34+CD33- cells influence days to engraftment and transfusion requirements in autologous blood stem-cell recipients.

1998 • 64 citations

Phase I/II study of combined granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor administration for the mobilization of hematopoietic progenitor cells.

1996 • 64 citations

Collection of peripheral blood progenitor cells after the administration of cyclophosphamide, etoposide, and granulocyte‐colony‐ stimulating factor: an analysis of 497 patients

1997 • 62 citations

Increased numbers of long-term culture-initiating cells in the apheresis product of patients randomized to receive increasing doses of stem cell factor administered in combination with chemotherapy and a standard dose of granulocyte colony-stimulating factor

1996 • 62 citations

Peripheral blood stem cells reach new heights [editorial; comment]

1993 • 61 citations

Allogeneic transplantation of selected CD34+ cells from peripheral blood: experience of 62 cases using immunoadsorption or immunomagnetic technique

1998 • 61 citations

Durability of hematopoiesis following autografting with peripheral blood hematopoietic progenitors

1994 • 59 citations

Characterization of human bone marrow fibroblast colony-forming cells (CFU-F) and their progeny

1980 • 57 citations

Increase of mobilized CD34-positive peripheral blood progenitor cells in patients with Hodgkin's disease, non-Hodgkin's lymphoma, and cancer of the testis.

1996 • 56 citations

Mobilization of peripheral-blood progenitor cells with high-dose etoposide and granulocyte colony-stimulating factor in patients with breast cancer, non-Hodgkin's lymphoma, and Hodgkin's disease.

1997 • 55 citations

Haemopoiesis of transplanted patients with autologous marrows assessed by long‐term marrow culture

1994 • 54 citations

Autologous Transplantation of Blood Stern Cells Mobilized with Filgrastim Alone in 93 Patients with Malignancies: The Number of CD34+ Cells Reinfused Is the Only Factor Predicting Both Granulocyte and Platelet Recovery

1996 • 53 citations

Allogeneic transplantation with blood stem cells mobilized by rhG-CSF for hematological malignancies.

1995 • 51 citations

Regulation of hemopoietic cell growth and development: experimental and clinical studies.

1989 • 51 citations

G‐CSF alone mobilizes sufficient peripheral blood CD34⁺ cells for positive selection in newly diagnosed patients with myeloma and lymphoma

1996 • 48 citations

Abnormalities of myeloid progenitor cells after "successful" bone marrow transplantation.

1985 • 47 citations

The optimization of collection of peripheral blood stem cells for autotransplantation in acute myeloid leukaemia.

1989 • 47 citations

Randomized comparison of progenitor-cell mobilization using chemotherapy, stem-cell factor, and filgrastim or chemotherapy plus filgrastim alone in patients with ovarian cancer.

1998 • 43 citations

Myelosuppressive conditioning improves autologous engraftment of genetically marked hematopoietic repopulating cells in dogs

1995 • 42 citations

Alloantigen presenting function of normal human CD34+ hematopoietic cells

1996 • 40 citations

Improved Priming for Mobilization of and Optimal Timing for Harvest of Peripheral Blood Stem Cells

1996 • 37 citations

Some factors determining the minimum number of cells required for successful clinical engraftment.

1995 • 37 citations

Peripheral blood stem cells reach new heights [editorial; comment]

1993 • 37 citations

IN SEARCH OF THE HAEMOPOIETIC STEM CELL

1995 • 36 citations

Blood stem cell transplantation: From preclinical to clinical models

1995 • 34 citations

The importance of CD34+/CD33− cells in platelet engraftment after intensive therapy for cancer patients given peripheral blood stem cell rescue

1998 • 32 citations

Hematopoietic recovery in cancer patients after transplantation of autologous peripheral blood CD34+ cells or unmanipulated peripheral blood stem and progenitor cells

1998 • 29 citations

Stem cells and stem cell transplantation.

1996 • 27 citations

Harvest Quality and Factors Affecting Collection and Engraftment of CD34+ Cells in Patients with Breast Cancer Scheduled for High-Dose Chemotherapy and Peripheral Blood Progenitor Cell Support

1997 • 26 citations

Stem cell factor leads to reduced blood processing during apheresis or the use of whole blood aliquots to support dose-intensive chemotherapy

1998 • 22 citations

Phase I trial of recombinant fusion protein PIXY321 for mobilization of peripheral-blood cells.

1996 • 20 citations

Multiple myeloma: reduced plasma cell contamination in peripheral blood progenitor cell collections performed after repeated high‐dose chemotherapy courses

1997 • 18 citations

Critique of the high-dose chemotherapy studies in breast cancer: a positive look at the data.

1999 • 18 citations

Physiological mechanisms in BMT and haemopoiesis--revisited.

1993 • 15 citations

THE ROLE OF SHEEP STROMA IN HUMAN HAEMOPOIESIS IN THE HUMAN/SHEEP CHIMAERAS

1996 • 14 citations

Phase II study of high-dose cyclophosphamide, etoposide, and carboplatin (CEC) followed by autologous hematopoietic stem cell rescue in women with metastatic or high-risk non-metastatic breast cancer: multivariate analysis of factors affecting survival and engraftment

1997 • 12 citations

P78. The stro-1 + cell fraction of adult human bone marrow contains the osteogenic precursors

1994 • 12 citations

Hematopoietic Stem Cell Transplantation: The Role of Granulocyte Colony-Stimulating Factor in Hematopoietic Stem Cell Transplantation

1997 • 11 citations

Clinical implications of the heterogeneity of hematopoietic progenitors elicited in peripheral blood by anticancer therapy with cyclophosphamide and cytokine(s)

1996 • 10 citations

Result of attempted hematopoietic reconstitution using isologous, peripheral blood mononuclear cells: a case report

1980 • 6 citations

Marrow engraftment by allogeneic leukocytes in lethally irradiated dogs

1968 • 6 citations

Peripheral blood progenitor cell (PBPC) transplantation with a single apheresis in patients with lymphoma, myeloma and solid tumors

1996 • 6 citations