Potential Adhesion Mechanisms for Localisation of Haemopoietic Progenitors to Bone Marrow Stroma

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Adhesion receptors of the immune system

1990 • 6,585 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

1991 • 2,806 citations

Bone marrow transplant

1999 • 2,452 citations

CD44 is the principal cell surface receptor for hyaluronate

1990 • 2,433 citations

The relationship between the spleen colony-forming cell and the haemopoietic stem cell.

1978 • 2,290 citations

Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins

1991 • 2,195 citations

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Endothelial Leukocyte Adhesion Molecule 1: an Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins

1989 • 2,045 citations

Integrins and other cell adhesion molecules

1990 • 1,990 citations

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

1990 • 1,836 citations

Signal transduction from the extracellular matrix.

1993 • 1,727 citations

Endothelial Expression of a Mononuclear Leukocyte Adhesion Molecule During Atherogenesis

1991 • 1,703 citations

VLA Proteins in the Integrin Family: Structures, Functions, and Their Role on Leukocytes

1990 • 1,592 citations

A cell-surface molecule involved in organ-specific homing of lymphocytes

1983 • 1,515 citations

Integrins.

1991 • 1,369 citations

Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1

1991 • 1,144 citations

Isolation of a candidate human hematopoietic stem-cell population.

1992 • 1,098 citations

Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons.

1992 • 1,040 citations

Structure and function of the leukocyte adhesion molecules CD11/CD18

1990 • 962 citations

PECAM-1 (CD31) Cloning and Relation to Adhesion Molecules of the Immunoglobulin Gene Superfamily

1990 • 948 citations

Effect of peripheral-blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy

1992 • 900 citations

Selectins.

1993 • 869 citations

Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis

1988 • 845 citations

Cytokines in context.

1991 • 808 citations

Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin.

1989 • 807 citations

Cloning of GMP-140, a granule membrane protein of platelets and endothelium: Sequence similarity to proteins involved in cell adhesion and inflammation

1989 • 799 citations

Structure and function of the leukocyte adhesion molecules CD11/CD18

1990 • 785 citations

Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the SId mutant

1991 • 740 citations

Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule.

1991 • 719 citations

Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins.

1991 • 713 citations

Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro

1989 • 699 citations

An endothelial ligand for L-Selectin is a novel mucin-like molecule

1992 • 660 citations

Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis.

1991 • 628 citations

Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures.

1990 • 574 citations

CD44 — A molecule involved in leukocyte adherence and T-cell activation

1989 • 559 citations

The cutaneous lymphocyte antigen is a skin lymphocyte homing receptor for the vascular lectin endothelial cell-leukocyte adhesion molecule 1.

1991 • 557 citations

Circulation of CD34+ hematopoietic stem cells in the peripheral blood of high-dose cyclophosphamide-treated patients: enhancement by intravenous recombinant human granulocyte-macrophage colony-stimulating factor

1989 • 549 citations

Cloning of a lymphocyte homing receptor reveals a lectin domain

1989 • 522 citations

Fibronectin and VLA-4 in haematopoietic stem cell–microenvironment interactions

1991 • 522 citations

Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells.

1992 • 519 citations

GMP-140 mediates adhesion of stimulated platelets to neutrophils

1990 • 515 citations

CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x.

1991 • 505 citations

Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia

1987 • 461 citations

Transforming growth factor-alpha. A model for membrane-anchored growth factors.

1990 • 430 citations

Comparison of haematological recovery times and supportive care requirements of autologous recovery phase peripheral blood stem cell transplants, autologous bone marrow transplants and allogeneic bone marrow transplants.

1992 • 427 citations

Regulation of hematopoiesis

1970 • 424 citations

Occupation of the extracellular matrix receptor, integrin, is a control point for myogenic differentiation

1987 • 419 citations

Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cells

1992 • 417 citations

Inducible cell adhesion molecule 110 (INCAM-110) is an endothelial receptor for lymphocytes. A CD11/CD18-independent adhesion mechanism.

1990 • 408 citations

Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma.

1992 • 388 citations

CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion.

1992 • 383 citations

Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation

1987 • 377 citations

Granulocyte-macrophage colony-stimulating factor and other cytokines regulate surface expression of the leukocyte adhesion molecule-1 on human neutrophils, monocytes, and their precursors.

1990 • 325 citations

Stromal cell associated haemopoiesis

1982 • 325 citations

Host origin of marrow stromal cells following allogeneic bone marrow transplantation

1987 • 323 citations

The ultrastructure of the hemopoietic environment of the marrow: a review.

1981 • 308 citations

Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor.

1991 • 308 citations

The hematopoietic microenvironment of the bone marrow: An ultrastructural study of the stroma in rats

1976 • 307 citations

Vascular and nonvascular expression of INCAM-110. A target for mononuclear leukocyte adhesion in normal and inflamed human tissues.

1991 • 306 citations

Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cells

1992 • 300 citations

The extended family of proteoglycans: social residents of the pericellular zone

1989 • 297 citations

The evolving role of autologous peripheral stem cell transplantation following high-dose therapy for malignancies [editorial]

1991 • 290 citations

Cells and Molecules that Regulate B Lymphopoiesis in Bone Marrow

1989 • 272 citations

Differentiation inhibiting activity is produced in matrix-associated and diffusible forms that are generated by alternate promoter usage

1990 • 271 citations

Multiple activation states of VLA-4. Mechanistic differences between adhesion to CS1/fibronectin and to vascular cell adhesion molecule-1.

1993 • 266 citations

Expression of the human leukocyte adhesion molecule, LAM1. Identity with the TQ1 and Leu-8 differentiation antigens.

1990 • 263 citations

CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1

1991 • 262 citations

Cell adhesion in the immune system

1993 • 262 citations

Vascular cell adhesion molecule-1 and the integrin VLA-4 mediate adhesion of human B cell precursors to cultured bone marrow adherent cells.

1991 • 234 citations

Differentiation of primitive human multipotent hematopoietic progenitors into single lineage clonogenic progenitors is accompanied by alterations in their interaction with fibronectin.

1991 • 224 citations

'Role of bone marrow stromal cells in the growth of human multiple myeloma

1991 • 223 citations

Transmembrane signalling by integrins

1992 • 219 citations

Molecular characterization and functional analysis of the leukocyte surface protein CD31.

1990 • 217 citations

Synthesis of membrane-bound colony-stimulating factor 1 (CSF-1) and downmodulation of CSF-1 receptors in NIH 3T3 cells transformed by cotransfection of the human CSF-1 and c-fms (CSF-1 receptor) genes.

1987 • 202 citations

'Role of bone marrow stromal cells in the growth of human multiple myeloma

1991 • 194 citations

Molecular basis of homing of intravenously transplanted stem cells to the marrow

1990 • 193 citations

Identification of a novel recognition sequence for the integrin alpha 4 beta 1 in the COOH-terminal heparin-binding domain of fibronectin.

1991 • 189 citations

Isolation of c-kit receptor-expressing cells from bone marrow, peripheral blood, and fetal liver: functional properties and composite antigenic profile

1991 • 188 citations

Extracellular matrix production by the adherent cells of long-term murine bone marrow cultures

1983 • 184 citations

Cellular interactions in haematopoiesis

1979 • 180 citations

Distribution of surface-membrane molecules on bone marrow and cord blood CD34+ hematopoietic cells.

1992 • 177 citations

Alpha 4 beta 1 and alpha 5 beta 1 are differentially expressed during myelopoiesis and mediate the adherence of human CD34+ cells to fibronectin in an activation-dependent way

1993 • 168 citations

CD34 expression is regulated reciprocally with adhesion molecules in vascular endothelial cells in vitro

1993 • 167 citations

Hemopoietic stromal microenvironment

1983 • 165 citations

A heterophilic adhesion mechanism for platelet/endothelial cell adhesion molecule 1 (CD31).

1992 • 160 citations

Hematopoietic progenitor cell expression of the H-CAM (CD44) homing- associated adhesion molecule

1990 • 160 citations

Blood cell cytoadhesion molecules.

1992 • 152 citations

Regulation of haemopoiesis in long-term bone marrow cultures. IV. Glycosaminoglycan synthesis and the stimulation of haemopoiesis by beta-D-xylosides.

1983 • 149 citations

Expression of integrins and examination of their adhesive function in normal and leukemic hematopoietic cells

1993 • 146 citations

CD44 can be activated to function as an hyaluronic acid receptor in normal murine T cells

1992 • 144 citations

Expression and function of adhesion molecules on human hematopoietic stem cells: CD34+ LFA-1- cells are more primitive than CD34+ LFA-1+ cells

1992 • 129 citations

Human hematopoietic stem cell adherence to cytokines and matrix molecules.

1992 • 129 citations

Coexpression of two fibronectin receptors, VLA-4 and VLA-5, by immature human erythroblastic precursor cells.

1991 • 122 citations

Platelet endothelial cell adhesion molecule, PECAM‐1, modulates cell migration

1992 • 120 citations

Roll, roll, roll your leucocyte gently down the vein.

1992 • 117 citations

The Haemopoietic Microenvironment

1979 • 117 citations

Expression of integrins in human bone marrow

1990 • 115 citations

Differential expression of LFA-1 molecules in non-Hodgkin's lymphoma and lymphoid leukemia

1988 • 114 citations

Immunohistochemical localization of membrane and alpha-granule proteins in human megakaryocytes: application to plastic-embedded bone marrow biopsy specimens

1986 • 114 citations

Thrombospondin functions as a cytoadhesion molecule for human hematopoietic progenitor cells

1990 • 107 citations

Binding of primitive hematopoietic progenitor cells to marrow stromal cells involves heparan sulfate

1992 • 104 citations

EXTRACELLULAR MATRIX OF THE MARROW MICROENVIRONMENT

1988 • 100 citations

Adhesive interactions of normal and leukemic human CD34+ myeloid progenitors: role of marrow stromal, fibroblast, and cytomatrix components.

1991 • 96 citations

Colony-stimulating factors; molecular and cellular biology

1990 • 93 citations

In vitro homing of hemopoietic stem cells is mediated by a recognition system with galactosyl and mannosyl specificities.

1987 • 86 citations

Interaction of human bone marrow fibroblasts with megakaryocytes: role of the c-kit ligand

1992 • 86 citations

Characterization of chemotherapy mobilized peripheral blood progenitor cells for use in autologous stem cell transplantation.

1992 • 84 citations

Cellular interactions

1988 • 81 citations

CD31, a novel cell surface marker for CD4 cells of suppressor lineage, unaltered by state of activation.

1992 • 71 citations

Marrow biology and stem cells.

1990 • 71 citations

Expression of intercellular adhesion molecule-1 (CD54) on hematopoietic progenitors

1991 • 70 citations

Interaction of human bone marrow fibroblasts with megakaryocytes: role of the c-kit ligand

1992 • 70 citations

Inhibition of normal rat kidney cell growth by transforming growth factor-β is mediated by collagen

1989 • 68 citations

BONE MARROW CONNECTIVE TISSUE AND THE HAEMOPOIETIC MICROENVIRONMENT

1982 • 65 citations

High-dose cyclophosphamide, carmustine, and etoposide followed by autologous peripheral stem cell transplantation for patients with relapsed Hodgkin's disease [published erratum appears in Blood 1991 Dec 15;78(12):3330]

1991 • 64 citations

Mechanisms of thymus homing

1993 • 62 citations

Cell Interactions In Vitro

1979 • 51 citations

Studies on hemopoietic microenvironments. Report of a workshop held in La Jolla,, California, August 8-9, 1974.

1975 • 50 citations

Developmental regulation of granulocytic cell binding to hemonectin

1990 • 33 citations

Cell surfaces and the regulation of hemopoiesis.

1978 • 24 citations

VLA molecule expression may be involved in the release of acute myeloid leukaemic cells from the bone marrow

1992 • 21 citations