Increased numbers of long-term culture-initiating cells in the apheresis product of patients randomized to receive increasing doses of stem cell factor administered in combination with chemotherapy and a standard dose of granulocyte colony-stimulating factor

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1990 • 1,448 citations

Effect of peripheral-blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy

1992 • 900 citations

Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38- progenitor cells

1991 • 869 citations

Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers.

1990 • 697 citations

Effects of recombinant human granulocyte colony-stimulating factor on hematopoietic progenitor cells in cancer patients

1988 • 600 citations

Flow cytometry for clinical estimation of circulating hematopoietic progenitors for autologous transplantation in cancer patients

1991 • 519 citations

Evidence for Stem Cells in the Peripheral Blood of Mice

1962 • 475 citations

The evaluation of limiting dilution assays

1982 • 458 citations

An in vitro limiting-dilution assay of long-term repopulating hematopoietic stem cells in the mouse

1989 • 406 citations

Autologous peripheral hematopoietic stem cell transplantation restores hematopoietic function following marrow ablative therapy

1988 • 388 citations

Defining a Therapeutic Dose of Peripheral Blood Stem Cells

1992 • 334 citations

Autologous transplantation of blood-derived hemopoietic stem cells after myeloablative therapy in a patient with Burkitt's lymphoma

1986 • 311 citations

Variance Component Models with Binary Response: Interviewer Variability

1985 • 272 citations

Use of limiting-dilution type long-term marrow cultures in frequency analysis of marrow-repopulating and spleen colony-forming hematopoietic stem cells in the mouse

1991 • 267 citations

Differential regulation of primitive human hematopoietic cells in long- term cultures maintained on genetically engineered murine stromal cells

1991 • 261 citations

Comparative effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy

1993 • 258 citations

Frequency analysis of human primitive haematopoietic stem cell subsets using a cobblestone area forming cell assay.

1994 • 246 citations

Cells Capable of Colony Formation in the Peripheral Blood of Man

1971 • 242 citations

In Vitro Growth of Granulocytic and Mononuclear Cell Colonies From Blood of Normal Individuals

1971 • 202 citations

Successful autologous transplantation with peripheral blood hemopoietic cells in a patient with acute leukemia.

1986 • 194 citations

Characterization of primitive hematopoietic cells in normal human peripheral blood

1992 • 172 citations

Direct comparison by limiting dilution analysis of long-term culture- initiating cells in human bone marrow, umbilical cord blood, and blood stem cells

1994 • 170 citations

Characterization of an erythroid precursor cell of high proliferative capacity in normal human peripheral blood.

1977 • 167 citations

Subsets of CD34+ cells and rapid hematopoietic recovery after peripheral-blood stem-cell transplantation.

1995 • 143 citations

Recombinant rat stem cell factor synergizes with recombinant human granulocyte colony-stimulating factor in vivo in mice to mobilize peripheral blood progenitor cells that have enhanced repopulating potential

1993 • 126 citations

Demonstration of hemopoietic stem cells in the peripheral blood of baboons by cross circulation

1977 • 116 citations

Kinetics of committed and primitive blood progenitor mobilization after chemotherapy and growth factor treatment and their use in autotransplants

1994 • 113 citations

Early lympho-hemopoietic recovery after autografting using peripheral blood stem cells in acute non-lymphoblastic leukemia.

1988 • 111 citations

Result of attempted hematopoietic reconstitution using isologous, peripheral blood mononuclear cells: a case report

1980 • 105 citations

Functional differences between CD38- and DR- subfractions of CD34+ bone marrow cells

1994 • 104 citations

Effects of granulocyte colony-stimulating factor and stem cell factor, alone and in combination, on the mobilization of peripheral blood cells that engraft lethally irradiated dogs

1994 • 101 citations

The ligand for c-kit, stem cell factor, stimulates the circulation of cells that engraft lethally irradiated baboons

1992 • 95 citations

Allogeneic Marrow Engraftment by Cross Circulation in Lethally Irradiated Dogs

1966 • 57 citations

Autografting with blood progenitor cells: predictive value of preapheresis blood cell counts on progenitor cell harvest and correlation of the reinfused cell dose with hematopoietic reconstitution

1995 • 51 citations

The capacity of peripheral blood stem cells mobilised with chemotherapy plus G-CSF to repopulate irradiated marrow stroma in vitro is similar to that of bone marrow

1992 • 49 citations

Demonstration of hemopoietic stem cells in the peripheral blood of baboons by cross circulation

1977 • 11 citations

Result of attempted hematopoietic reconstitution using isologous, peripheral blood mononuclear cells: a case report

1980 • 6 citations