Methodology of long-term culture of human hemopoietic cells

Bone marrow transplant

1989 • 3,423 citations

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

The Human Hematopoietic Colony-Stimulating Factors

1987 • 1,728 citations

Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis

1988 • 845 citations

Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers.

1990 • 697 citations

Long-term culture of human bone marrow cells.

1980 • 624 citations

Long-Term Marrow Culture Reveals Chromosomally Normal Hematopoietic Progenitor Cells in Patients with Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia

1983 • 335 citations

Identification in culture of a class of hemopoietic colony-forming units with extensive capability to self-renew and generate multipotential hemopoietic colonies.

1982 • 317 citations

Enzymatic treatment of long-term human marrow cultures reveals the preferential location of primitive hemopoietic progenitors in the adherent layer

1983 • 296 citations

Human marrow cells capable of erythropoietic differentiation in vitro: definition of three erythroid colony responses

1977 • 278 citations

Sensitivity of corticosteroid-dependent insulin-resistant lipogenesis in marrow preadipocytes of obese-diabetic (db/db) mice

1978 • 231 citations

Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. I. Stimulatory role of a variety of mesenchymal cell activators and inhibitory role of TGF-beta

1990 • 227 citations

Growth and Differentiation in the Hemopoietic System

1987 • 220 citations

Hemopoietic colonies: in vitro cloning of normal and leukemic cells.

1977 • 202 citations

Unregulated proliferation of primitive chronic myeloid leukemia progenitors in the presence of normal marrow adherent cells.

1986 • 191 citations

Hemopoietic Colonies

1977 • 156 citations

Successful autografting in chronic myeloid leukaemia after maintenance of marrow in culture.

1989 • 149 citations

Regulated proliferation of primitive hematopoietic progenitor cells in long-term human marrow cultures

1985 • 144 citations

Hemoglobins in Development and Differentiation

1982 • 110 citations

Expansion in vitro of retrovirally marked totipotent hematopoietic stem cells

1990 • 100 citations

The role of cells and their products in the regulation of in vitro stem cell proliferation and granulocyte development

1980 • 84 citations

High-efficiency gene transfer to human hematopoietic cells maintained in long-term marrow culture [see comments]

1989 • 83 citations

Long-term marrow culture of cells from patients with acute myelogenous leukemia. Selection in favor of normal phenotypes in some but not all cases.

1985 • 82 citations

Close range cell:cell interaction required for stem cell maintenance in continuous bone marrow culture.

1981 • 77 citations

The use of bone marrow cells grown in long-term culture for autologous bone marrow transplantation in acute myeloid leukaemia: an update.

1989 • 75 citations

Human granulocytes generated in continuous bone marrow culture are physiologically normal

1981 • 64 citations

Generation of purified stromal cell cultures that support lymphoid and myeloid precursors

1986 • 57 citations

Survival of granulocytic progenitors in the nonadherent and adherent compartments of human long-term marrow cultures.

1984 • 55 citations

The human hematopoietic stem cell in vitro and in vivo.

1992 • 54 citations

Use of long-term human marrow cultures to demonstrate progenitor cell precursors in marrow treated with 4-hydroperoxycyclophosphamide.

1987 • 47 citations

CFU-S in individual erythroid colonies derived in vitro from adult mouse marrow

1979 • 45 citations

Clinical signficance of long-term cultures of myeloid blood cells

1987 • 40 citations

D. Metcalf, Hemopoietic Colonies. In Vitro Cloning of Normal and Leukemic Cells (Reihe: Recent Results in Cancer Research, Vol. 61). 227 S., 54 Abb., 28 Tab. Berlin‐Heidelberg‐New York 1977. Springer‐Verlag. DM 68,00

1979 • 37 citations

Human Stem Cells in Culture

1984 • 35 citations

CM Affi-Gel Blue chromatography of human urine: a simple one-step procedure for obtaining erythropoietin suitable for in vitro erythropoietic progenitor assays

1984 • 22 citations

Role of stromal populations in hemopoietic stem cell proliferation. I. Physically distinct subpopulations of hemopoietic stem cells and stromal progenitors determine long-term culture hemopoiesis.

1987 • 20 citations

Regulation of hemopoietic progenitor cell proliferation.

1988 • 7 citations