Hematopoietic regulators: redundancy or subtlety?

Structural design and molecular evolution of a cytokine receptor superfamily.

1990 • 2,104 citations

Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor

1992 • 2,004 citations

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

1990 • 1,763 citations

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

1989 • 1,411 citations

The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells

1989 • 1,097 citations

The IL-6 Signal Transducer, gp130: an Pncostatin M Receptor and Affinity Converter for the LIF Receptor

1992 • 897 citations

Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium

1990 • 837 citations

Expression cloning of the murine erythropoietin receptor

1989 • 776 citations

Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor.

1989 • 711 citations

Cloning of the human and murine interleukin-7 receptors: Demonstration of a soluble form and homology to a new receptor superfamily

1990 • 614 citations

Effects of recombinant human granulocyte colony-stimulating factor on hematopoietic progenitor cells in cancer patients

1988 • 600 citations

The Hemopoietic Colony-stimulating Factors

1995 • 565 citations

Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors.

1988 • 528 citations

Human interleukin 6 is a direct promoter of maturation of megakaryocytes in vitro.

1989 • 430 citations

Interleukin-6 is a potent thrombopoietic factor in vivo in mice

1989 • 422 citations

Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6.

1991 • 372 citations

Expression cloning of a receptor for murine granulocyte colony-stimulating factor

1990 • 362 citations

Hemopoietic responses in mice injected with purified recombinant murine GM-CSF.

1987 • 284 citations

Distribution of cells bearing receptors for a colony-stimulating factor (CSF-1) in murine tissues.

1981 • 239 citations

Binding of125I-labeled granulocyte colony-stimulating factor to normal murine hemopoietic cells

1985 • 215 citations

Delayed hematopoietic development in osteopetrotic (op/op) mice.

1993 • 196 citations

Human recombinant erythropoietin promotes differentiation of murine megakaryocytes in vitro.

1987 • 191 citations

The mechanism of action of erythropoietin

1986 • 185 citations

Correction by CSF-1 of defects in the osteopetrotic op/op mouse suggests local, developmental, and humoral requirements for this growth factor.

1991 • 183 citations

Direct proliferative actions of stem cell factor on murine bone marrow cells in vitro: effects of combination with colony-stimulating factors.

1991 • 180 citations

Rhodamine123 reveals heterogeneity within murine Lin-, Sca-1+ hemopoietic stem cells.

1992 • 160 citations

Colony Stimulating Factors

1981 • 154 citations

Stem cell factor induces proliferation and differentiation of highly enriched murine hematopoietic cells.

1991 • 146 citations

The leukemia inhibitory factor (LIF)

1991 • 127 citations

Lineage commitment of hemopoietic progenitor cells in developing blast cell colonies: influence of colony-stimulating factors.

1991 • 117 citations

Expression of the M-CSF receptor is controlled posttranscriptionally by the dominant actions of GM-CSF or multi-CSF

1990 • 109 citations

Chronic neutropenia. A new canine model induced by human granulocyte colony-stimulating factor.

1991 • 109 citations

Expression cloning of a cDNA encoding the murine interleukin 4 receptor based on ligand binding.

1990 • 108 citations

Coexpression of granulocyte-macrophage colony-stimulating factor, gamma interferon, and interleukins 3 and 4 is random in murine alloreactive T-lymphocyte clones.

1988 • 106 citations

Binding of iodinated multipotential colony‐stimulating factor (interleukin‐3) to murine bone marrow cells

1986 • 85 citations

Synergistic interactions between hematopoietic growth factors as detected by in vitro mouse bone marrow colony formation.

1988 • 66 citations

Differentiation of an interleukin 3-dependent precursor B-cell clone into immunoglobulin-producing cells in vitro.

1988 • 62 citations

The SCL gene product is regulated by and differentially regulates cytokine responses during myeloid leukemic cell differentiation.

1993 • 53 citations

Enhanced suppression of human myeloid leukemic cell lines by combinations of IL‐6, LIF, GM‐CSF and G‐CSF

1990 • 53 citations

Molecular structure of the IL‐3, GM‐CSF and IL‐5 receptors

1992 • 51 citations

Rat stem cell factor and IL-6 preferentially support the proliferation of c-kit-positive murine hemopoietic cells rather than their differentiation.

1993 • 42 citations

Induction of colony-stimulating factor receptor expression on hematopoietic progenitor cells: proposed mechanism for growth factor synergism

1992 • 35 citations

Reduced response to granulocyte colony-stimulating factor in W/Wv and Sl/Sld mice.

1991 • 31 citations