Group I mGluRs Coupled to G Proteins Are Regulated by Tyrosine Kinase in Dopamine Neurons of the Rat Midbrain

The functional anatomy of basal ganglia disorders

1989 • 5,166 citations

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

1995 • 3,456 citations

PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS

1997 • 3,070 citations

The metabotropic glutamate receptors: Structure and functions

1995 • 2,269 citations

Neuronal Calcium Signaling

1998 • 2,126 citations

Dopamine in schizophrenia: a review and reconceptualization

1991 • 1,963 citations

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

1996 • 1,946 citations

Interactions between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease

1990 • 1,102 citations

Homer Binds a Novel Proline-Rich Motif and Links Group 1 Metabotropic Glutamate Receptors with IP3 Receptors

1998 • 852 citations

Metabotropic glutamate receptors in brain function and pathology

1993 • 799 citations

Metabotropic glutamate receptors: electrophysiological properties and role in plasticity

1999 • 770 citations

Morphology and electrophysiological properties of immunocytochemically identified rat dopamine neurons recorded in vitro

1989 • 734 citations

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1

1994 • 730 citations

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

1999 • 724 citations

Metabotropic glutamate receptors: Synaptic transmission, modulation, and plasticity

1994 • 713 citations

Two types of neurone in the rat ventral tegmental area and their synaptic inputs.

1992 • 682 citations

Regulation of NMDA receptors by tyrosine kinases and phosphatases

1994 • 671 citations

Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: An in situ hybridization study in adult and developing rat

1992 • 645 citations

The Mitogen-Activated Protein Kinase Cascade Couples PKA and PKC to cAMP Response Element Binding Protein Phosphorylation in Area CA1 of Hippocampus

1999 • 542 citations

Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat

1994 • 512 citations

Two cell types in rat substantia nigra zona compacta distinguished by membrane properties and the actions of dopamine and opioids

1989 • 426 citations

Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.

1979 • 382 citations

G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors

1999 • 371 citations

On the potassium conductance increase activated by GABAB and dopamine D2 receptors in rat substantia nigra neurones.

1988 • 336 citations

Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement.

1994 • 333 citations

Phenylglycine derivatives as antagonists of metabotropic glutamate receptors

1994 • 303 citations

Glutamate mediates an inhibitory postsynaptic potential in dopamine neurons

1998 • 285 citations

Increased Probability of GABA Release during Withdrawal from Morphine

1997 • 279 citations

3,5‐Dihydroxyphenylglycine Is a Highly Selective Agonist for Phosphoinositide‐Linked Metabotropic Glutamate Receptors in the Rat Hippocampus

1994 • 270 citations

Tyrphostins. II. Heterocyclic and .alpha.-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases

1991 • 260 citations

Electrophysiology of dopaminergic and non‐dopaminergic neurones of the guinea‐pig substantia nigra pars compacta in vitro.

1991 • 257 citations

Properties of the Hyperpolarization‐activated Cation Current l_h in Rat Midbrain Dopaminergic Neurons

1995 • 210 citations

Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors.

1994 • 197 citations

G-protein-independent signaling mediated by metabotropic glutamate receptors

1999 • 174 citations

A Long-Lasting Calcium-Activated Nonselective Cationic Current Is Generated by Synaptic Stimulation or Exogenous Activation of Group I Metabotropic Glutamate Receptors in CA1 Pyramidal Neurons

1997 • 174 citations

Activation of a nonselective cationic conductance by metabotropic glutamatergic and muscarinic agonists in CA3 pyramidal neurons of the rat hippocampus

1995 • 168 citations

The Second Intracellular Loop of Metabotropic Glutamate Receptor 1 Cooperates with the Other Intracellular Domains to Control Coupling to G-proteins

1996 • 155 citations

Activation of Mitogen‐Activated Protein Kinase in Cultured Rat Hippocampal Neurons by Stimulation of Glutamate Receptors

1995 • 155 citations

Postsynaptic Current Mediated by Metabotropic Glutamate Receptors in Cerebellar Purkinje Cells

1998 • 150 citations

Expression and Coupling to Polyphosphoinositide Hydrolysis of Group I Metabotropic Glutamate Receptors in Early Postnatal and Adult Rat Brain

1997 • 149 citations

RGS4 Inhibits Signaling by Group I Metabotropic Glutamate Receptors

1998 • 146 citations

Activation of the extracellular signal‐regulated kinase 2 by metabotropic glutamate receptors

1999 • 144 citations

Activation of p42 Mitogen‐Activated Protein Kinase by Glutamate Receptor Stimulation in Rat Primary Cortical Cultures

1993 • 141 citations

Activation of the G Protein Gq/11 Through Tyrosine Phosphorylation of the α Subunit

1997 • 134 citations

Interactions between Ca2+ mobilizing mechanisms in cultured rat cerebellar granule cells.

1992 • 128 citations

Metabotropic glutamate receptors and the generation of locomotor activity: Interactions with midbrain dopamine

1999 • 116 citations

Trans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons

1994 • 113 citations

Protein Tyrosine Kinase Activity and Its Endogenous Substrates in Rat Brain: A Subcellular and Regional Survey

1988 • 108 citations

Regulation of locomotor activity by metabotropic glutamate receptors in the nucleus accumbens and ventral tegmental area.

2000 • 105 citations

Requirement of Protein Synthesis for Group I mGluR-Mediated Induction of Epileptiform Discharges

1998 • 98 citations

Tyrosine Kinase Is Required for Long-Term Depression in the Cerebellum

1996 • 96 citations

Phosphorylation of Mitogen‐Activated Protein Kinase in Cultured Rat Cortical Glia by Stimulation of Metabotropic Glutamate Receptors

1998 • 96 citations

Diversity of Calcium Signaling by Metabotropic Glutamate Receptors

1998 • 77 citations

Group I Metabotropic Glutamate Receptors Mediate an Inward Current in Rat Substantia Nigra Dopamine Neurons That Is Independent From Calcium Mobilization

1999 • 70 citations

Activation of metabotropic glutamate receptors induces an inward current in rat dopamine mesencephalic neurons

1993 • 69 citations

Metabotropic Glutamate Receptor Agonists Alter Neuronal Excitability and Ca²⁺Levels via the Phospholipase C Transduction Pathway in Cultured Purkinje Neurons

1997 • 63 citations

Glutamate Metabotropic Receptor Agonists Depress Excitatory and Inhibitory Transmission on Rat Mesencephalic Principal Neurons

1997 • 62 citations

A Slow Excitatory Postsynaptic Current Mediated by G‐protein‐coupled Metabotropic Glutamate Receptors in Rat Ventral Tegmental Dopamine Neurons

1997 • 60 citations

Regulation of the Nigrostriatal Pathway by Metabotropic Glutamate Receptors during Development

1998 • 58 citations

Phospholipase C-Independent Group I Metabotropic Glutamate Receptor-Mediated Inward Current in Mouse Purkinje Cells

1998 • 57 citations

Expression of metabotropic glutamate receptor 1 isoforms in the substantia nigra pars compacta of the rat

1998 • 55 citations

Metabotropic glutamate receptors are necessary for sensitization by amphetamine

1998 • 54 citations

Characterization of the inward current induced by metabotropic glutamate receptor stimulation in rat ventromedial hypothalamic neurones

1997 • 51 citations

Tyrosine kinases and synaptic transmission

1998 • 49 citations

Ca2+ signaling pathways linked to glutamate receptor activation in the somatic and dendritic regions of cultured cerebellar purkinje neurons

1996 • 49 citations

Metabotropic glutamate receptors: an original family of G protein‐coupled receptors

1993 • 46 citations

Postnatal Age and Protein Tyrosine Phosphorylation at Synapses in the Developing Rat Brain

1991 • 45 citations

Tyrosine kinase inhibitors enhance a Ca(2+)‐activated K+ current (IAHP) and reduce IAHP suppression by a metabotropic glutamate receptor agonist in rat dentate granule neurones.

1996 • 38 citations

This and That: hair pigments, the hypoxic basis of life and the Virgilian journey of the spermatozoon

1992 • 36 citations

Metabotropic glutamate receptor-mediated inhibition and excitation of substantia nigra dopamine neurons

1997 • 34 citations

1S,3R-ACPD-preferring Inward current in rat dorsolateral septal neurons is mediated by a novel excitatory amino acid receptor

1995 • 24 citations

Increased perinuclear Ca2+ activity evoked by metabotropic glutamate receptor activation in rat hippocampal neurones.

1995 • 18 citations