G-protein-independent signaling mediated by metabotropic glutamate receptors

PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS

1997 • 3,070 citations

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

1996 • 1,946 citations

β-Arrestin-Dependent Formation of β ₂ Adrenergic Receptor-Src Protein Kinase Complexes

1999 • 1,427 citations

Culturing nerve cells

1998 • 1,304 citations

Differential Presynaptic Localization of Metabotropic Glutamate Receptor Subtypes in the Rat Hippocampus

1997 • 1,105 citations

Coupling of mGluR/Homer and PSD-95 Complexes by the Shank Family of Postsynaptic Density Proteins

1999 • 1,024 citations

The metabotropic glutamate receptor (mGluRlα) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction

1993 • 905 citations

Homer Binds a Novel Proline-Rich Motif and Links Group 1 Metabotropic Glutamate Receptors with IP3 Receptors

1998 • 852 citations

Perisynaptic Location of Metabotropic Glutamate Receptors mGluR1 and mGluR5 on Dendrites and Dendritic Spines in the Rat Hippocampus

1996 • 845 citations

Metabotropic glutamate receptors: electrophysiological properties and role in plasticity

1999 • 770 citations

Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor

1995 • 737 citations

Glutamate stimulates inositol phosphate formation in striatal neurones

1985 • 734 citations

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

1999 • 724 citations

Regulation of NMDA receptors by tyrosine kinases and phosphatases

1994 • 671 citations

Kainate receptors mediate a slow postsynaptic current in hippocampal CA3 neurons

1997 • 551 citations

Signal transduction by the Wnt family of ligands

1998 • 474 citations

Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors

1997 • 469 citations

The synaptic activation of kainate receptors

1997 • 417 citations

Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.

1979 • 382 citations

Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb

1993 • 355 citations

Activation of metabotropic glutamate receptor type 2/3 suppresses transmission at rat hippocampal mossy fibre synapses.

1996 • 341 citations

Src Activation in the Induction of Long-Term Potentiation in CA1 Hippocampal Neurons

1998 • 329 citations

Heptahelical Receptor Signaling: Beyond the G Protein Paradigm

1999 • 323 citations

Inhibition of uptake unmasks rapid extracellular turnover of glutamate of nonvesicular origin

1999 • 311 citations

(RS)-2-Chloro-5-Hydroxyphenylglycine (CHPG) Activates mGlu5, but not mGlu1, Receptors Expressed in CHO Cells and Potentiates NMDA Responses in the Hippocampus

1997 • 306 citations

Dependence of an adenosine-activated potassium current on a GTP-binding protein in mammalian central neurons

1987 • 254 citations

Rhodopsin-family receptors associate with small G proteins to activate phospholipase D

1998 • 211 citations

Regulation of c-Src tyrosine kinase activity by the Src SH2 domain.

1993 • 208 citations

Regulation of potassium channels by protein kinases

1996 • 201 citations

A purinergic component of the excitatory postsynaptic current mediated by P2X receptors in the CA1 neurons of the rat hippocampus

1998 • 199 citations

Phosphotyrosyl-protein phosphatase of TCRC-2 cells.

1982 • 195 citations

Adenosine increases synaptic facilitation in the in vitro rat hippocampus: evidence for a presynaptic site of action.

1985 • 193 citations

Modulation of Ca2+ channels by PTX-sensitive G-proteins is blocked by N- ethylmaleimide in rat sympathetic neurons

1994 • 182 citations

Phenylglycine derivatives discriminate between mGluR1- and mGluR5-mediated responses

1995 • 175 citations

A Long-Lasting Calcium-Activated Nonselective Cationic Current Is Generated by Synaptic Stimulation or Exogenous Activation of Group I Metabotropic Glutamate Receptors in CA1 Pyramidal Neurons

1997 • 174 citations

Pharmacological characterization of 1-aminoindan-1,5-dicarboxylic acid, a potent mGluR1 antagonist.

1997 • 173 citations

Activation of a nonselective cationic conductance by metabotropic glutamatergic and muscarinic agonists in CA3 pyramidal neurons of the rat hippocampus

1995 • 168 citations

Differential Regulation of Proline-rich Tyrosine Kinase 2/Cell Adhesion Kinase β (PYK2/CAKβ) and pp125FAK by Glutamate and Depolarization in Rat Hippocampus

1996 • 135 citations

Glutamate mediates a slow synaptic response in hippocampal slice cultures

1991 • 134 citations

Reactive sulfhydryl groups of alpha 39, a guanine nucleotide-binding protein from brain. Location and function.

1987 • 97 citations

Phosphorylation of Mitogen‐Activated Protein Kinase in Cultured Rat Cortical Glia by Stimulation of Metabotropic Glutamate Receptors

1998 • 96 citations

Mechanism of vanadate-induced activation of tyrosine phosphorylation and of the respiratory burst in HL60 cells. Role of reduced oxygen metabolites

1991 • 90 citations

G protein-coupled receptors mediate a fast excitatory postsynaptic current in CA3 pyramidal neurons in hippocampal slices

1995 • 57 citations

Ionotropic and metabotropic neurotransmission

1979 • 53 citations

Tyrosine kinases and synaptic transmission

1998 • 49 citations

Glutamate activates a K+ conductance increase in aplysia neurons that appears to be independent of G proteins

1994 • 34 citations

Inhibition of a slow synaptic response by a metabotropic glutamate receptor antagonist in hippocampal CA3 pyramidal cells

1993 • 27 citations

1S,3R-ACPD-preferring Inward current in rat dorsolateral septal neurons is mediated by a novel excitatory amino acid receptor

1995 • 24 citations

8 Chemoattractant receptor signaling G Protein-dependent and-independent pathways

1997 • 17 citations

A peptide activator of endogenous tyrosine kinase enhances synaptic currents mediated by NMDA receptors

1998 • 14 citations