Murine GBP-2: A New IFN-γ-Induced Member of the GBP Family of GTPases Isolated from Macrophages

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

Regulation of the mevalonate pathway

1990 • 5,282 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Proteins regulating Ras and its relatives

1993 • 1,930 citations

STATs: Signal Transducers and Activators of Transcription

1996 • 1,414 citations

Cytokine signal transduction

1994 • 1,358 citations

The Molecular Cell Biology of Interferon-gamma and its Receptor

1993 • 1,323 citations

p21ras is modified by a farnesyl isoprenoid.

1989 • 847 citations

Protein Prenyltransferases

1996 • 693 citations

[20] Isolation of RNA using guanidinium salts

1987 • 614 citations

Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus

1982 • 611 citations

GTP-binding domain: three consensus sequence elements with distinct spacing.

1987 • 602 citations

Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity.

1992 • 542 citations

Posttranslational modification of proteins by isoprenoids in mammalian cells

1990 • 515 citations

Evidence for a gamma-interferon receptor that regulates macrophage tumoricidal activity.

1984 • 471 citations

Development and applications of a molecular genetic linkage map of the mouse genome

1991 • 427 citations

Biology of the Macrophage

1986 • 416 citations

Role of interferon-gamma in immune cell regulation.

1995 • 374 citations

Protein Prenylation: a Mediator of Protein-Protein Interactions

1993 • 346 citations

Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation.

1990 • 333 citations

Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins.

1993 • 318 citations

Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons.

1991 • 278 citations

A Model for the Tertiary Structure of p21, the Product of the ras Oncogene

1985 • 248 citations

Rab GDP Dissociation Inhibitor: Putting Rab GTPases in the Right Place

1995 • 240 citations

Interferon induction of fibroblast proteins with guanylate binding activity.

1983 • 197 citations

The prenylation of proteins

1992 • 160 citations

Interactions of alpha- and gamma-interferon in the transcriptional regulation of the gene encoding a guanylate-binding protein.

1989 • 159 citations

The interferon-induced 67-kDa guanylate-binding protein (hGBP1) is a GTPase that converts GTP to GMP

1994 • 149 citations

Interferon Regulatory Factor 1 Is Required for Mouse Gbp Gene Activation by Gamma Interferon

1995 • 140 citations

Two distinct alpha-interferon-dependent signal transduction pathways may contribute to activation of transcription of the guanylate-binding protein gene.

1991 • 132 citations

Isoprenoid modification and plasma membrane association: critical factors for ras oncogenicity.

1991 • 126 citations

Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.

1991 • 125 citations

Interferon action: induction of specific proteins in mouse and human cells by homologous interferons.

1979 • 118 citations

Roles of Lipid Modifications of Transducin Subunits in Their GDP-Dependent Association and Membrane Binding

1994 • 82 citations

Affinity purification of an interferon-induced human guanylate-binding protein and its characterization.

1985 • 79 citations

Farnesol Is Utilized for Protein Isoprenylation and the Biosynthesis of Cholesterol in Mammalian Cells

1995 • 77 citations

Polylysine domain of K-ras 4B protein is crucial for malignant transformation.

1994 • 73 citations

Prenylation of an interferon-γ-induced GTP-binding protein: the human guanylate binding protein, huGBP1

1996 • 68 citations

Genetic control of interferon action: Mouse strain distribution and inheritance of an induced protein with guanylate-binding property

1984 • 68 citations

The Gene for the Retinal Pigment Epithelium-Specific Protein RPE65 Is Localized to Human 1p31 and Mouse 3

1994 • 65 citations

Interferon-γ: A Key Immunoregulatory Lymphokine

1993 • 62 citations

Interferon induction of gene transcription analyzed by in vivo footprinting.

1992 • 61 citations

The guanine‐nucleotide binding proteins EMBO‐NATO‐CEC advanced research workshop organized by L. Bosch, B. Kraal and A. Parmeggiani in Renesse, The Netherlands, August 6–11, 1988

1988 • 56 citations

GTPase properties of the interferon‐induced human guanylate‐binding protein 2

1996 • 55 citations

Identification and characterization of a new gene family induced during macrophage activation.

1991 • 54 citations

[1] Isolation of RNA

1989 • 53 citations

The Human Interferon‐γ Receptor System

1987 • 49 citations

Utilization of Geranylgeraniol for Protein Isoprenylation in C6 Glial Cells

1994 • 46 citations

Chicken Guanylate-binding Protein

1996 • 42 citations

Promoter analysis of an interferon-inducible gene associated with macrophage activation.

1994 • 36 citations

Immunologic Effects of Interferon

1990 • 35 citations

Molecular cloning and characterization of an isoprenylated 67 kDa protein

1994 • 28 citations

Different mRNAs induced by interferon in cells from inbred mouse strains A/J and A2G

1983 • 24 citations

Rat p67 GBP Is Induced by Interferon-γ and Isoprenoid-Modified in Macrophages

1996 • 22 citations

Regulators of Small GTPases

2007 • 21 citations

Induction of a prenylated 65-kd protein in macrophages by interferon or lipopolysaccharide

1995 • 10 citations