Switching the in vivo specificity of a minimal Hox-responsive element

Homeobox genes and axial patterning

1992 • 2,688 citations

Homeodomain-DNA recognition

1994 • 784 citations

Genetic Control of Wing Disc Development in Drosophila

1975 • 584 citations

Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain

1989 • 566 citations

Protein traffic on the heat shock promoter: Parking, stalling, and trucking along

1993 • 507 citations

The sequence specificity of homeodomain-DNA interaction

1988 • 501 citations

Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx

1995 • 493 citations

Divergent homeo box proteins recognize similar DNA sequences in Drosophila

1988 • 491 citations

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins.

1995 • 396 citations

Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins

1996 • 393 citations

The DNA binding specificity of ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein

1994 • 378 citations

DNA binding specificity of homeodomains

1991 • 300 citations

Pbx Modulation of Hox Homeodomain Amino-Terminal Arms Establishes Different DNA-Binding Specificities across theHoxLocus

1996 • 274 citations

Positive cross-regulation and enhancer sharing: two mechanisms for specifying overlapping Hox expression patterns.

1997 • 272 citations

Guidebook to the Homeobox Genes

1995 • 270 citations

extradenticle Raises the DNA binding specificity of homeotic selector gene products

1994 • 269 citations

extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1

1993 • 264 citations

Detecting conserved regulatory elements with the model genome of the Japanese puffer fish, Fugu rubripes.

1995 • 257 citations

Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity.

1990 • 239 citations

Autoregulation of a drosophila homeotic selector gene

1988 • 229 citations

Cooperative Interactions between HOX and PBX Proteins Mediated by a Conserved Peptide Motif

1995 • 224 citations

Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3

1993 • 215 citations

The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins.

1994 • 207 citations

Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila.

1991 • 184 citations

The specificity of homeotic gene function

1995 • 167 citations

Coordinate regulation of downstream genes by extradenticle and the homeotic selector proteins.

1994 • 157 citations

Differential DNA sequence recognition is a determinant of specificity in homeotic gene action.

1992 • 146 citations

Both Pbx1 and E2A-Pbx1 Bind the DNA Motif ATCAATCAA Cooperatively with the Products of Multiple Murine Hox Genes, Some of Which Are Themselves Oncogenes

1995 • 146 citations

Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomain is critical to functional specificity

1993 • 142 citations

DEAF-1, a novel protein that binds an essential region in a Deformed response element.

1996 • 138 citations

Control of Drosophila adult pattern by extradenticle.

1995 • 134 citations

Control of morphogenesis and differentiation by HOM/Hox genes

1993 • 128 citations

Regulation of the mec-3 gene by the C.elegans homeoproteins UNC-86 and MEC-3.

1992 • 125 citations

Nuclear import of the homeodomain protein Extradenticle in response to Wg and Dpp signalling

1996 • 121 citations

An extradenticle-induced conformational change in a HOX protein overcomes an inhibitory function of the conserved hexapeptide motif.

1996 • 117 citations

Hox Homeodomain Proteins Exhibit Selective Complex Stabilities with Pbx and DNA

1996 • 114 citations

The segment identity functions of Ultrabithorax are contained within its homeo domain and carboxy-terminal sequences.

1993 • 112 citations

Structural Determinants within Pbx1 That Mediate Cooperative DNA Binding with Pentapeptide-Containing Hox Proteins: Proposal for a Model of a Pbx1-Hox-DNA Complex

1996 • 110 citations

extradenticle determines segmental identities throughout Drosophila development

1995 • 109 citations

A structural model for a homeotic protein-extradenticle-DNA complex accounts for the choice of HOX protein in the heterodimer.

1996 • 108 citations

An autoregulatory element of the murine Hox-4.2 gene.

1992 • 107 citations

Engrailed and Hox homeodomain proteins contain a related Pbx interaction motif that recognizes a common structure present in Pbx.

1996 • 106 citations

High-affinity binding sites for the Deformed protein are required for the function of an autoregulatory enhancer of the Deformed gene.

1991 • 99 citations

An autoregulatory enhancer element of the Drosophila homeotic gene Deformed.

1990 • 96 citations

Functional specificity of the Antennapedia homeodomain.

1993 • 89 citations

Induction of labial expression in the Drosophila endoderm: response elements for dpp signalling and for autoregulation

1992 • 87 citations

Control of expression of the homeotic labial (lab) locus of Drosophila melanogaster. evidence for both positive and negative autogenous regulation

1991 • 84 citations

Yeast a1 and α2 Homeodomain Proteins Form a DNA-binding Activity with Properties Distinct from those of either Protein

1993 • 78 citations

Deformed protein binding sites and cofactor binding sites are required for the function of a small segment-specific regulatory element in Drosophila embryos.

1994 • 72 citations

A universal target sequence is bound in vitro by diverse homeodomains

1993 • 71 citations

Comparative analysis of chicken Hoxb-4 regulation in transgenic mice

1995 • 55 citations

Recognition of a DNA operator by a dimer composed of two different homeodomain proteins.

1994 • 54 citations

A synthetic homeodomain binding site acts as a cell type specific, promoter specific enhancer in Drosophila embryos.

1990 • 48 citations

Deformedexpression in theDrosophilacentral nervous system is controlled by an autoactivated intronic enhancer

1995 • 32 citations

A screen for modifiers of Deformed function in Drosophila.

1995 • 32 citations