Regulation of the mec-3 gene by the C.elegans homeoproteins UNC-86 and MEC-3.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

THE GENETICS OF CAENORHABDITIS ELEGANS

1974 • 14,589 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences.

1991 • 3,108 citations

Vectors for selective expression of cloned DNAs by T7 RNA polymerase

1987 • 1,449 citations

Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: A framework for understanding homeodomain-DNA interactions

1990 • 996 citations

Developmental genetics of the mechanosensory neurons of Caenorhabditis elegans

1981 • 757 citations

Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo-and a Cys–His domain

1990 • 684 citations

A modular set of lacZ fusion vectors for studying gene expression in Caenorhabditis elegans

1990 • 618 citations

The unc-86 gene product couples cell lineage and cell identity in C. elegans

1990 • 606 citations

mec-3, a homeobox-containing gene that specifies differentiation of the touch receptor neurons in C. elegans

1988 • 573 citations

Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II

1990 • 550 citations

The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration

1991 • 548 citations

A single amino acid can determine the DNA binding specificity of homeodomain proteins

1989 • 531 citations

Mutations that lead to reiterations in the cell lineages of C. elegans

1981 • 530 citations

Divergent homeo box proteins recognize similar DNA sequences in Drosophila

1988 • 491 citations

DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9

1989 • 487 citations

POU-domain transcription factors: pou-er-ful developmental regulators.

1991 • 461 citations

Genetic Control of Differentiation of the Caenorhabditis elegans Touch Receptor Neurons

1989 • 344 citations

The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors

1988 • 334 citations

The mec-3 gene of Caenorhabditis elegans requires its own product for maintained expression and is expressed in three neuronal cell types.

1989 • 321 citations

dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo.

1992 • 309 citations

mec-7 is a beta-tubulin gene required for the production of 15-protofilament microtubules in Caenorhabditis elegans.

1989 • 292 citations

Regulation of transcription and cell identity by POU domain proteins

1991 • 233 citations

Myogenesis and developmental control genes

1990 • 121 citations

Phage lambda cDNA cloning vectors for subtractive hybridization, fusion-protein synthesis and Cre-loxP automatic plasmid subcloning

1990 • 106 citations

Autoregulation - a common property of eukaryotic transcription factors?

1989 • 88 citations

Organogenesis in C. elegans: Positioning of neurons and muscles in the egg-laying system

1990 • 87 citations

The mec-3 gene contains cis-acting elements mediating positive and negative regulation in cells produced by asymmetric cell division in Caenorhabditis elegans.

1991 • 77 citations

The LIM region of a presumptive Caenorhabditis elegans transcription factor is an iron-sulfur- and zinc-containing metallodomain.

1991 • 61 citations

The DNA-binding homeo domain of the Oct-2 protein.

1989 • 59 citations

Transcriptional control and the integration of cell-autonomous and environmental cues during development

1990 • 15 citations