Engrailed and Hox homeodomain proteins contain a related Pbx interaction motif that recognizes a common structure present in Pbx.

Calculation of protein extinction coefficients from amino acid sequence data

1989 • 5,198 citations

Homeobox genes and axial patterning

1992 • 2,688 citations

Hox genes in vertebrate development

1994 • 2,057 citations

The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes.

1989 • 912 citations

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B all

1990 • 726 citations

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

1990 • 692 citations

Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins

1984 • 686 citations

The sequence specificity of homeodomain-DNA interaction

1988 • 501 citations

Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx

1995 • 493 citations

Divergent homeo box proteins recognize similar DNA sequences in Drosophila

1988 • 491 citations

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins.

1995 • 396 citations

The DNA binding specificity of ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein

1994 • 378 citations

Homeobox genes: Their function in Drosophila segmentation and pattern formation

1994 • 288 citations

PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1.

1991 • 280 citations

Determination of the Nuclear Magnetic Resonance Solution Structure of an Antennapedia Homeodomain-DNA Complex

1993 • 270 citations

extradenticle Raises the DNA binding specificity of homeotic selector gene products

1994 • 269 citations

extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1

1993 • 264 citations

Crystal Structure of the MATa1/MATα2 Homeodomain Heterodimer Bound to DNA

1995 • 260 citations

Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity.

1990 • 239 citations

Cooperative Interactions between HOX and PBX Proteins Mediated by a Conserved Peptide Motif

1995 • 224 citations

The specificities of sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain

1990 • 189 citations

Coordinate regulation of HOX genes in human hematopoietic cells.

1991 • 171 citations

The Pentapeptide Motif of Hox Proteins Is Required for Cooperative DNA Binding with Pbx1, Physically Contacts Pbx1, and Enhances DNA Binding by Pbx1

1995 • 167 citations

Coordinate regulation of downstream genes by extradenticle and the homeotic selector proteins.

1994 • 157 citations

The Pancreatic Islet Factor STF-1 Binds Cooperatively with Pbx to a Regulatory Element in the Somatostatin Promoter: Importance of the FPWMK Motif and of the Homeodomain

1995 • 152 citations

Both Pbx1 and E2A-Pbx1 Bind the DNA Motif ATCAATCAA Cooperatively with the Products of Multiple Murine Hox Genes, Some of Which Are Themselves Oncogenes

1995 • 146 citations

Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomain is critical to functional specificity

1993 • 142 citations

A homeodomain substitution changes the regulatory specificity of the Deformed protein in drosophila embryos

1989 • 142 citations

Mapping functional specificity in the Dfd and Ubx homeo domains.

1992 • 134 citations

Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions

1992 • 130 citations

A comprehensive classification of homeobox genes

1994 • 124 citations

Extradenticle protein is a selective cofactor for the Drosophila homeotics: role of the homeodomain and YPWM amino acid motif in the interaction.

1995 • 122 citations

A short, disordered protein region mediates interactions between the homeodomain of the yeast α2 protein and the MCM1 protein

1993 • 120 citations

The segment identity functions of Ultrabithorax are contained within its homeo domain and carboxy-terminal sequences.

1993 • 112 citations

PBX2 and PBX3, New Homeobox Genes with Extensive Homology to the Human Proto-Oncogene PBX1

1991 • 108 citations

The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins.

1995 • 104 citations

Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2

1995 • 87 citations

Interaction between two homeodomain proteins is specified by a short C-terminal tail

1994 • 59 citations

Dpbx, a new homeobox gene closely related to the human proto-oncogene pbxl molecular structure and developmental expression

1993 • 58 citations

37 A Combinatorial Regulatory Circuit in Budding Yeast

1992 • 53 citations

NMR structure determination reveals that the homeodomain is connected through a flexible linker to the main body in the Drosophila Antennapedia protein.

1992 • 53 citations

Interaction between two homeodomain proteins is specified by a short C-terminal tail

1994 • 2 citations