Reduced Number and Function of CD4+ CD25 high FoxP3 + Regulatory T Cells in Patients with Systemic Lupus Erythematosus

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

2003 • 7,470 citations

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

2001 • 3,260 citations

CD4+CD25high Regulatory Cells in Human Peripheral Blood

2001 • 1,882 citations

Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis

2004 • 1,835 citations

Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes

2005 • 825 citations

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

2006 • 773 citations

Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution

2000 • 679 citations

Dysfunctional Blood and Target Tissue CD4+CD25high Regulatory T Cells in Psoriasis: Mechanism Underlying Unrestrained Pathogenic Effector T Cell Proliferation

2005 • 561 citations

Scurfin (FOXP3) Acts as a Repressor of Transcription and Regulates T Cell Activation

2001 • 551 citations

Certified Professionals

2001 • 533 citations

CD4+CD25+ regulatory T cells in rheumatoid arthritis: Differences in the presence, phenotype, and function between peripheral blood and synovial fluid

2004 • 526 citations

Global Natural Regulatory T Cell Depletion in Active Systemic Lupus Erythematosus

2005 • 457 citations

The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs

2005 • 439 citations

Blockade of CTLA-4 on CD4+CD25+ Regulatory T Cells Abrogates Their Function In Vivo

2006 • 422 citations

Quantification of regulatory T cells in patients with systemic lupus erythematosus

2003 • 417 citations

Defective Suppressor Function of Human CD4+ CD25+ Regulatory T Cells in Autoimmune Polyglandular Syndrome Type II

2004 • 359 citations

Control of Autoimmunity by Naturally Arising Regulatory CD4+ T Cells

2003 • 292 citations

Decreased CD4⁺CD25⁺ T Cells in Peripheral Blood of Patients with Systemic Lupus Erythematosus

2004 • 286 citations

Where CD4+CD25+ T reg cells impinge on autoimmune diabetes

2005 • 266 citations

Regulatory T cells in patients with systemic lupus erythematosus

2006 • 247 citations

Inverse correlation between CD4⁺ regulatory T‐cell population and autoantibody levels in paediatric patients with systemic lupus erythematosus

2006 • 172 citations

Enrichment of CD4+ CD25high T cell population in patients with systemic lupus erythematosus treated with glucocorticoids

2006 • 146 citations