VE-cadherin and β-catenin binding dynamics during histamine-induced endothelial hyperpermeability

Signaling Mechanisms Regulating Endothelial Permeability

2005 • 1,632 citations

Regulation of Cadherin Adhesive Activity

2000 • 793 citations

The Structure of the β-Catenin/E-Cadherin Complex and the Molecular Basis of Diverse Ligand Recognition by β-Catenin

2001 • 737 citations

Vascular endothelial–cadherin is an important determinant of microvascular integrityinvivo

1999 • 659 citations

Regulation of E-cadherin/Catenin Association by Tyrosine Phosphorylation

1999 • 589 citations

The Juxtamembrane Region of the Cadherin Cytoplasmic Tail Supports Lateral Clustering, Adhesive Strengthening, and Interaction with p120ctn

1998 • 566 citations

Crystal Structure of a β-Catenin/Tcf Complex

2000 • 388 citations

Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase

2004 • 356 citations

Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions.

1996 • 334 citations

Inhibition of Wnt signaling by ICAT, a novel β-catenin-interacting protein

2000 • 331 citations

Vascular Permeability Factor/Vascular Endothelial Cell Growth Factor-mediated Permeability Occurs through Disorganization of Endothelial Junctional Proteins

1998 • 320 citations

Tyrosine Phosphorylation of VE-cadherin Prevents Binding of p120- and β-Catenin and Maintains the Cellular Mesenchymal State

2005 • 318 citations

Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes

2004 • 310 citations

Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability

2001 • 293 citations

Mechanisms regulating endothelial cell barrier function

2000 • 244 citations

Wnt/β-Catenin Signaling Induces Proliferation, Survival and Interleukin-8 in Human Endothelial Cells

2005 • 244 citations

Histamine Induces Tyrosine Phosphorylation of Endothelial Cell-to-Cell Adherens Junctions

1999 • 229 citations

Endothelial Gaps as Sites for Plasma Leakage in Inflammation

1999 • 222 citations

Endothelial-dependent Mechanisms Regulate Leukocyte Transmigration: A Process Involving the Proteasome and Disruption of the Vascular Endothelial–Cadherin Complex at Endothelial Cell-to-Cell Junctions

1997 • 182 citations

VE-cadherin: adhesion at arm's length

2004 • 180 citations

Histamine increases venular permeability via a phospholipase C-NO synthase-guanylate cyclase cascade

1993 • 174 citations

ICAT Inhibits β-Catenin Binding to Tcf/Lef-Family Transcription Factors and the General Coactivator p300 Using Independent Structural Modules

2002 • 168 citations

Thermodynamics of β-Catenin-Ligand Interactions

2005 • 152 citations

Activated Neutrophils Induce Hyperpermeability and Phosphorylation of Adherens Junction Proteins in Coronary Venular Endothelial Cells

1999 • 138 citations

VE-cadherin-p120 interaction is required for maintenance of endothelial barrier function

2004 • 135 citations

The Crystal Structure of the β-Catenin/ICAT Complex Reveals the Inhibitory Mechanism of ICAT

2002 • 117 citations

Interaction of PKC and NOS in signal transduction of microvascular hyperpermeability

1997 • 112 citations

Protein Kinase C Activation Contributes to Microvascular Barrier Dysfunction in the Heart at Early Stages of Diabetes

2000 • 101 citations

Histamine stimulates phosphorylation of adherens junction proteins and alters their link to vimentin

2002 • 98 citations

Mobility and cytoskeletal interactions of cell adhesion receptors

1999 • 98 citations

Role of cadherins and plakoglobin in interendothelial adhesion under resting conditions and shear stress

1997 • 96 citations

Myosin Light Chain Phosphorylation in Neutrophil-Stimulated Coronary Microvascular Leakage

2002 • 95 citations

Reversibility of increased microvessel permeability in response to VE-cadherin disassembly

2000 • 95 citations

Signal Transduction Pathways in Enhanced Microvascular Permeability

2000 • 92 citations

Histamine alters endothelial barrier function at cell-cell and cell-matrix sites

2000 • 88 citations

Sphingosine 1-phosphate rapidly increases endothelial barrier function independently of VE-cadherin but requires cell spreading and Rho kinase

2007 • 87 citations

Cadherin-5 redistribution at sites of TNF-α and IFN-γ-induced permeability in mesenteric venules

1999 • 86 citations

Microvascular Permeability in Diabetes and Insulin Resistance

2007 • 84 citations

Src-dependent, neutrophil-mediated vascular hyperpermeability and β-catenin modification

2002 • 78 citations

Role for ICAT in β-catenin-dependent nuclear signaling and cadherin functions

2004 • 74 citations

Inflammatory mediators induce sequestration of VE-cadherin in cultured human endothelial cells.

2000 • 73 citations

Polyamines regulate β-catenin tyrosine phosphorylation via Ca²⁺ during intestinal epithelial cell migration

2002 • 63 citations

The protein kinase MEK1/2 mediate vascular endothelial growth factor‐ and histamine‐induced hyperpermeability in porcine coronary venules

2004 • 61 citations

Involvement of ROCK-mediated endothelial tension development in neutrophil-stimulated microvascular leakage

2005 • 60 citations

Effect of Histamine on Endothelial Permeability and Structure and Adhesion Molecules of the Paracellular Junctions of Perfused Human Placental Microvessels

1995 • 56 citations

Changes in endothelial actin cytoskeleton in venules with time after histamine treatment

1995 • 56 citations

Placental Trophoblast-Derived Factors Diminish Endothelial Barrier Function

2004 • 47 citations

Regulation of endothelial permeability by second messengers.

1996 • 28 citations

Signal Transduction Pathways in Enhanced Microvascular Permeability

2000 • 25 citations

Transference of recombinant VE‐cadherin cytoplasmic domain alters endothelial junctional integrity and porcine microvascular permeability

2003 • 24 citations

PKC-dependent, burn-induced adherens junction reorganization and barrier dysfunction in pulmonary microvascular endothelial cells

2005 • 23 citations

Endothelial Gaps as Sites for Plasma Leakage in Inflammation

1999 • 17 citations