Thermodynamics of β-Catenin-Ligand Interactions

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

Wnt signalling in stem cells and cancer

2005 • 3,593 citations

Rapid measurement of binding constants and heats of binding using a new titration calorimeter

1989 • 2,603 citations

Deconstructing the Cadherin-Catenin-Actin Complex

2005 • 993 citations

α-Catenin Is a Molecular Switch that Binds E-Cadherin-β-Catenin and Regulates Actin-Filament Assembly

2005 • 956 citations

The Structure of the β-Catenin/E-Cadherin Complex and the Molecular Basis of Diverse Ligand Recognition by β-Catenin

2001 • 737 citations

Drosophila Tcf and Groucho interact to repress Wingless signalling activity

1998 • 722 citations

A minimal peptide substrate in biotin holoenzyme synthetase‐catalyzed biotinylation

1999 • 702 citations

The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

1998 • 679 citations

Three-Dimensional Structure of the Armadillo Repeat Region of β-Catenin

1997 • 678 citations

Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly.

1994 • 633 citations

Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex

2004 • 629 citations

Use of Peptide Libraries to Map the Substrate Specificity of a Peptide-Modifying Enzyme: A 13 Residue Consensus Peptide Specifies Biotinylation in Escherichia coli

1993 • 586 citations

β-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation

2005 • 516 citations

Crystal Structure of a β-Catenin/Tcf Complex

2000 • 388 citations

Exact Analysis of Competition Ligand Binding by Displacement Isothermal Titration Calorimetry

2000 • 362 citations

All Tcf HMG box transcription factors interact with Groucho-related co-repressors

2001 • 358 citations

Inhibition of Wnt signaling by ICAT, a novel β-catenin-interacting protein

2000 • 331 citations

Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes

2004 • 310 citations

Mechanism of Phosphorylation-Dependent Binding of APC to β-Catenin and Its Role in β-Catenin Degradation

2004 • 299 citations

Coupling Assembly of the E-Cadherin/β-Catenin Complex to Efficient Endoplasmic Reticulum Exit and Basal-lateral Membrane Targeting of E-Cadherin in Polarized MDCK Cells

1999 • 289 citations

Regulation of β-Catenin Structure and Activity by Tyrosine Phosphorylation

2001 • 258 citations

The Cadherin Cytoplasmic Domain Is Unstructured in the Absence of β-Catenin

2001 • 248 citations

Crystal structure of a β-catenin/Axin complex suggests a mechanism for the β-catenin destruction complex

2003 • 234 citations

β-Catenin–Histone Deacetylase Interactions Regulate the Transition of LEF1 from a Transcriptional Repressor to an Activator

2000 • 214 citations

NEW EMBO MEMBER'S REVIEW: T-cell factors: turn-ons and turn-offs

2002 • 203 citations

Biochemical and mutational analysis of a plant virus polyprotein cleavage site.

1988 • 197 citations

Structure of a human Tcf4-beta-catenin complex.

2001 • 190 citations

Tcf4 can specifically recognize beta-catenin using alternative conformations.

2001 • 189 citations

ICAT Inhibits β-Catenin Binding to Tcf/Lef-Family Transcription Factors and the General Coactivator p300 Using Independent Structural Modules

2002 • 168 citations

Distinguishing roles of the membrane-cytoskeleton and cadherin mediated cell-cell adhesion in generating different Na+,K(+)-ATPase distributions in polarized epithelia.

1993 • 155 citations

Crystal Structure of a β-Catenin/APC Complex Reveals a Critical Role for APC Phosphorylation in APC Function

2004 • 152 citations

Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex

2001 • 132 citations

The Crystal Structure of the β-Catenin/ICAT Complex Reveals the Inhibitory Mechanism of ICAT

2002 • 117 citations

Hot Spots in Tcf4 for the Interaction with β-Catenin

2003 • 81 citations

Molecular genetic and biochemical evidence for the involvement of the heptapeptide cleavage sequence in determining the reaction profile at two tobacco etch virus cleavage sites in cell-free assays

1989 • 73 citations

β-Catenin N- and C-terminal Tails Modulate the Coordinated Binding of Adherens Junction Proteins to β-Catenin

2002 • 67 citations

Thermodynamics of the high-affinity interaction of TCF4 with β-catenin

2001 • 64 citations

β-Catenin and Plakoglobin N- and C-tails Determine Ligand Specificity

2004 • 53 citations

The amino- and carboxyl-terminal tails of β-catenin reduce its affinity for desmoglein 2

2000 • 42 citations

Systematic Peptide Array-based Delineation of the Differential β-Catenin Interaction with Tcf4, E-Cadherin, and Adenomatous Polyposis Coli

2005 • 31 citations

Differences Between the Interaction of β-Catenin with Non-phosphorylated and Single-mimicked Phosphorylated 20-amino acid Residue Repeats of the APC Protein

2003 • 17 citations