Defective dendritic cell migration and activation of adaptive immunity in PI3Kγ-deficient mice
Data up to Jan 2025
Total Citations Per Year
Abstract
References (65)
Dendritic cells and the control of immunity
1998 • 14,345 citations
Immunobiology of Dendritic Cells
2000 • 6,653 citations
The Dendritic Cell System and its Role in Immunogenicity
1991 • 4,733 citations
Chemokines
2000 • 3,773 citations
Tolerogenic Dendritic Cells
2003 • 3,131 citations
Chemokines and leukocyte traffic
1998 • 2,755 citations
CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs
1999 • 2,326 citations
Renal and Extrarenal Effects of Gum Arabic (Acacia Senegal) - What Can be Learned from Animal Experiments?
2013 • 2,289 citations
LEUKOCYTE LOCOMOTION AND CHEMOTAXIS
1973 • 1,709 citations
Origin, maturation and antigen presenting function of dendritic cells
1997 • 1,375 citations
Central Role for G Protein-Coupled Phosphoinositide 3-Kinase γ in Inflammation
2000 • 1,209 citations
A Putative Chemokine Receptor, BLR1, Directs B Cell Migration to Defined Lymphoid Organs and Specific Anatomic Compartments of the Spleen
1996 • 1,125 citations
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 • 1,031 citations
Mice Lacking Expression of Secondary Lymphoid Organ Chemokine Have Defects in Lymphocyte Homing and Dendritic Cell Localization
1999 • 1,030 citations
Roles of PLC-β2 and -β3 and PI3Kγ in Chemoattractant-Mediated Signal Transduction
2000 • 825 citations
Macrophage inflammatory protein-1
2004 • 709 citations
Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution
2000 • 679 citations
Cloning and Characterization of a G Protein-Activated Human Phosphoinositide-3 Kinase
1995 • 673 citations
Chemokines in tissue-specific and microenvironment-specific lymphocyte homing
2000 • 643 citations
Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties.
1998 • 627 citations
Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies.
1987 • 592 citations
The Gβγ Sensitivity of a PI3K Is Dependent upon a Tightly Associated Adaptor, p101
1997 • 549 citations
Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization.
1990 • 543 citations
Up-Regulation of Macrophage Inflammatory Protein-3α/CCL20 and CC Chemokine Receptor 6 in Psoriasis
2000 • 533 citations
The role of chemokines in linking innate and adaptive immunity
2002 • 487 citations
Cutting Edge: Differential Regulation of Chemokine Receptors During Dendritic Cell Maturation: A Model for Their Trafficking Properties
1998 • 486 citations
Epstein-Barr Virus–induced Molecule 1 Ligand Chemokine Is Expressed by Dendritic Cells in Lymphoid Tissues and Strongly Attracts Naive T Cells and Activated B Cells
1998 • 479 citations
Mobilizing Dendritic Cells for Tolerance, Priming, and Chronic Inflammation
1999 • 474 citations
The Dendritic Cell Populations of Mouse Lymph Nodes
2001 • 461 citations
Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets
1994 • 391 citations
Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets.
1993 • 347 citations
Cutting Edge: Selective Usage of Chemokine Receptors by Plasmacytoid Dendritic Cells
2001 • 328 citations
Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines.
1995 • 318 citations
Prostaglandin E2–EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells
2003 • 312 citations
The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7
1998 • 311 citations
Leukocytes navigate by compass: roles of PI3Kγ and its lipid products
2000 • 298 citations
Phosphoinositide 3-Kinase γ Is an Essential Amplifier of Mast Cell Function
2002 • 293 citations
Role of the Parasite-Derived Prostaglandin D2 in the Inhibition of Epidermal Langerhans Cell Migration during Schistosomiasis Infection
2001 • 273 citations
Cc Chemokine Receptor (Ccr)2 Is Required for Langerhans Cell Migration and Localization of T Helper Cell Type 1 (Th1)-Inducing Dendritic Cells
2000 • 273 citations
Macrophage Inflammatory Protein 3α Is Involved in the Constitutive Trafficking of Epidermal Langerhans Cells
1999 • 272 citations
Roles of Gβγ in membrane recruitment and activation of p110γ/p101 phosphoinositide 3-kinase γ
2002 • 237 citations
CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses
2001 • 218 citations
Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice
2002 • 196 citations
Pertussis toxin inhibits migration of B and T lymphocytes into splenic white pulp cords.
1995 • 183 citations
Visualization and Characterization of Migratory Langerhans Cells in Murine Skin and Lymph Nodes by Antibodies Against Langerin/CD207
2003 • 177 citations
The Dendritic Cell System And Its Role In Immunogenicity
1991 • 174 citations
Selective Suppression of IL-12 Production by Chemoattractants
2000 • 169 citations
The chemokine receptor switch paradigm and dendritic cell migration: its significance in tumor tissues
2000 • 169 citations
Combined Natural Killer Cell and Dendritic Cell Functional Deficiency in KARAP/DAP12 Loss-of-Function Mutant Mice
2000 • 165 citations
Travellers in many guises: The origins and destinations of dendritic cells
2002 • 161 citations
Differential responsiveness to constitutive vs. inducible chemokines of immature and mature mouse dendritic cells
1999 • 150 citations
Osteopontin Is Involved in the Initiation of Cutaneous Contact Hypersensitivity by Inducing Langerhans and Dendritic Cell Migration to Lymph Nodes
2001 • 130 citations
Chemokines and dendritic cells: A crucial alliance
2002 • 126 citations
Lipids on the move: phosphoinositide 3-kinases in leukocyte function
2000 • 123 citations
Do phosphoinositide 3-kinases direct lymphocyte navigation?
2003 • 121 citations
A Strikingly Constant Ratio Exists Between Langerhans Cells and Other Epidermal Cells in Human Skin. A Stereologic Study Using the Optical Disector Method and the Confocal Laser Scanning Microscope11Presented in part at the International Investigative Dermatology 1998, Cologne, Germany 1998.
2001 • 112 citations
Primary Role for GI Protein Signaling in the Regulation of Interleukin 12 Production and the Induction of T Helper Cell Type 1 Responses
2000 • 108 citations
Dendritic Cells Require T Cells for Functional Maturation In Vivo
1999 • 107 citations
The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node
2001 • 96 citations
Dual Role of Dendritic Cells in the Induction and Down-Regulation of Antigen-Specific Cutaneous Inflammation
1998 • 89 citations
Phosphatidylinositol 3-Kinase Regulates the CD4/CD8 T Cell Differentiation Ratio
2003 • 82 citations
An improved isolation method for murine migratory cutaneous dendritic cells
1996 • 63 citations
Phosphoinositide 3-Kinases in Inunimity: Lessons from Knockout Mice
2002 • 52 citations
Defective migration of monocyte-derived dendritic cells in LAD-1 immunodeficiency
2002 • 24 citations
OSTEOPONTIN IS INVOLVED IN THE INITIATION OF CUTANEOUS CONTACT HYPERSENSITIVITY BY INDUCING LANGERHANS AND DENDRITIC CELL MIGRATION TO LYMPH NODES
2002 • 15 citations