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Defective dendritic cell migration and activation of adaptive immunity in PI3Kγ-deficient mice

Data up to Jan 2025

Published2004
Citations147
References65

Total Citations Per Year

Abstract

References (65)

Dendritic cells and the control of immunity

1998 • 14,345 citations

Immunobiology of Dendritic Cells

2000 • 6,653 citations

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Chemokines

2000 • 3,773 citations

Tolerogenic Dendritic Cells

2003 • 3,131 citations

Chemokines and leukocyte traffic

1998 • 2,755 citations

CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs

1999 • 2,326 citations

Renal and Extrarenal Effects of Gum Arabic (Acacia Senegal) - What Can be Learned from Animal Experiments?

2013 • 2,289 citations

LEUKOCYTE LOCOMOTION AND CHEMOTAXIS

1973 • 1,709 citations

Origin, maturation and antigen presenting function of dendritic cells

1997 • 1,375 citations

Central Role for G Protein-Coupled Phosphoinositide 3-Kinase γ in Inflammation

2000 • 1,209 citations

A Putative Chemokine Receptor, BLR1, Directs B Cell Migration to Defined Lymphoid Organs and Specific Anatomic Compartments of the Spleen

1996 • 1,125 citations

Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration

2000 • 1,031 citations

Mice Lacking Expression of Secondary Lymphoid Organ Chemokine Have Defects in Lymphocyte Homing and Dendritic Cell Localization

1999 • 1,030 citations

Roles of PLC-β2 and -β3 and PI3Kγ in Chemoattractant-Mediated Signal Transduction

2000 • 825 citations

Macrophage inflammatory protein-1

2004 • 709 citations

Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution

2000 • 679 citations

Cloning and Characterization of a G Protein-Activated Human Phosphoinositide-3 Kinase

1995 • 673 citations

Chemokines in tissue-specific and microenvironment-specific lymphocyte homing

2000 • 643 citations

Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties.

1998 • 627 citations

Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies.

1987 • 592 citations

The Gβγ Sensitivity of a PI3K Is Dependent upon a Tightly Associated Adaptor, p101

1997 • 549 citations

Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization.

1990 • 543 citations

Up-Regulation of Macrophage Inflammatory Protein-3α/CCL20 and CC Chemokine Receptor 6 in Psoriasis

2000 • 533 citations

The role of chemokines in linking innate and adaptive immunity

2002 • 487 citations

Cutting Edge: Differential Regulation of Chemokine Receptors During Dendritic Cell Maturation: A Model for Their Trafficking Properties

1998 • 486 citations

Epstein-Barr Virus–induced Molecule 1 Ligand Chemokine Is Expressed by Dendritic Cells in Lymphoid Tissues and Strongly Attracts Naive T Cells and Activated B Cells

1998 • 479 citations

Mobilizing Dendritic Cells for Tolerance, Priming, and Chronic Inflammation

1999 • 474 citations

The Dendritic Cell Populations of Mouse Lymph Nodes

2001 • 461 citations

Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets

1994 • 391 citations

Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets.

1993 • 347 citations

Cutting Edge: Selective Usage of Chemokine Receptors by Plasmacytoid Dendritic Cells

2001 • 328 citations

Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines.

1995 • 318 citations

Prostaglandin E2–EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells

2003 • 312 citations

The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7

1998 • 311 citations

Leukocytes navigate by compass: roles of PI3Kγ and its lipid products

2000 • 298 citations

Phosphoinositide 3-Kinase γ Is an Essential Amplifier of Mast Cell Function

2002 • 293 citations

Role of the Parasite-Derived Prostaglandin D2 in the Inhibition of Epidermal Langerhans Cell Migration during Schistosomiasis Infection

2001 • 273 citations

Cc Chemokine Receptor (Ccr)2 Is Required for Langerhans Cell Migration and Localization of T Helper Cell Type 1 (Th1)-Inducing Dendritic Cells

2000 • 273 citations

Macrophage Inflammatory Protein 3α Is Involved in the Constitutive Trafficking of Epidermal Langerhans Cells

1999 • 272 citations

Roles of Gβγ in membrane recruitment and activation of p110γ/p101 phosphoinositide 3-kinase γ

2002 • 237 citations

CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses

2001 • 218 citations

Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice

2002 • 196 citations

Pertussis toxin inhibits migration of B and T lymphocytes into splenic white pulp cords.

1995 • 183 citations

Visualization and Characterization of Migratory Langerhans Cells in Murine Skin and Lymph Nodes by Antibodies Against Langerin/CD207

2003 • 177 citations

The Dendritic Cell System And Its Role In Immunogenicity

1991 • 174 citations

Selective Suppression of IL-12 Production by Chemoattractants

2000 • 169 citations

The chemokine receptor switch paradigm and dendritic cell migration: its significance in tumor tissues

2000 • 169 citations

Combined Natural Killer Cell and Dendritic Cell Functional Deficiency in KARAP/DAP12 Loss-of-Function Mutant Mice

2000 • 165 citations

Travellers in many guises: The origins and destinations of dendritic cells

2002 • 161 citations

Differential responsiveness to constitutive vs. inducible chemokines of immature and mature mouse dendritic cells

1999 • 150 citations

Osteopontin Is Involved in the Initiation of Cutaneous Contact Hypersensitivity by Inducing Langerhans and Dendritic Cell Migration to Lymph Nodes

2001 • 130 citations

Chemokines and dendritic cells: A crucial alliance

2002 • 126 citations

Lipids on the move: phosphoinositide 3-kinases in leukocyte function

2000 • 123 citations

Do phosphoinositide 3-kinases direct lymphocyte navigation?

2003 • 121 citations

A Strikingly Constant Ratio Exists Between Langerhans Cells and Other Epidermal Cells in Human Skin. A Stereologic Study Using the Optical Disector Method and the Confocal Laser Scanning Microscope11Presented in part at the International Investigative Dermatology 1998, Cologne, Germany 1998.

2001 • 112 citations

Primary Role for GI Protein Signaling in the Regulation of Interleukin 12 Production and the Induction of T Helper Cell Type 1 Responses

2000 • 108 citations

Dendritic Cells Require T Cells for Functional Maturation In Vivo

1999 • 107 citations

The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node

2001 • 96 citations

Dual Role of Dendritic Cells in the Induction and Down-Regulation of Antigen-Specific Cutaneous Inflammation

1998 • 89 citations

Phosphatidylinositol 3-Kinase Regulates the CD4/CD8 T Cell Differentiation Ratio

2003 • 82 citations

An improved isolation method for murine migratory cutaneous dendritic cells

1996 • 63 citations

Phosphoinositide 3-Kinases in Inunimity: Lessons from Knockout Mice

2002 • 52 citations

Defective migration of monocyte-derived dendritic cells in LAD-1 immunodeficiency

2002 • 24 citations

OSTEOPONTIN IS INVOLVED IN THE INITIATION OF CUTANEOUS CONTACT HYPERSENSITIVITY BY INDUCING LANGERHANS AND DENDRITIC CELL MIGRATION TO LYMPH NODES

2002 • 15 citations

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