Cc Chemokine Receptor (Ccr)2 Is Required for Langerhans Cell Migration and Localization of T Helper Cell Type 1 (Th1)-Inducing Dendritic Cells

Dendritic cells and the control of immunity

1998 • 14,345 citations

CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs

1999 • 2,326 citations

CHEMOKINE RECEPTORS AS HIV-1 CORECEPTORS: Roles in Viral Entry, Tropism, and Disease

1999 • 2,174 citations

Current protocols in immunology

1992 • 1,464 citations

Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation

1998 • 1,190 citations

A Putative Chemokine Receptor, BLR1, Directs B Cell Migration to Defined Lymphoid Organs and Specific Anatomic Compartments of the Spleen

1996 • 1,125 citations

Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.

1997 • 1,078 citations

Chemokines and Cell Migration in Secondary Lymphoid Organs

1999 • 1,046 citations

Mice Lacking Expression of Secondary Lymphoid Organ Chemokine Have Defects in Lymphocyte Homing and Dendritic Cell Localization

1999 • 1,030 citations

CD8α+ and CD8α− Subclasses of Dendritic Cells Direct the Development of Distinct T Helper Cells In Vivo

1999 • 998 citations

Differentiation of Phagocytic Monocytes into Lymph Node Dendritic Cells In Vivo

1999 • 904 citations

Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1

2000 • 820 citations

A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1

1998 • 810 citations

B Cell–attracting Chemokine 1, a Human CXC Chemokine Expressed in Lymphoid Tissues, Selectively Attracts B Lymphocytes via BLR1/CXCR5

1998 • 807 citations

Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo.

1996 • 800 citations

Defects in Macrophage Recruitment and Host Defense in Mice Lacking the CCR2 Chemokine Receptor

1997 • 700 citations

Distinct patterns and kinetics of chemokine production regulate dendritic cell function

1999 • 692 citations

Lymphocyte Trafficking and Regional Immunity

1999 • 686 citations

Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2

1997 • 671 citations

Migration and maturation of Langerhans cells in skin transplants and explants.

1990 • 663 citations

Requirement of Mip-1α for an Inflammatory Response to Viral Infection

1995 • 636 citations

Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies.

1987 • 592 citations

In Vivo Detection of Dendritic Cell Antigen Presentation to CD4+ T Cells

1997 • 560 citations

Lymphotoxin α/β and Tumor Necrosis Factor Are Required for Stromal Cell Expression of Homing Chemokines in B and T Cell Areas of the Spleen

1999 • 552 citations

Genetically resistant mice lacking interleukin‐12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response

1996 • 483 citations

Mobilizing Dendritic Cells for Tolerance, Priming, and Chronic Inflammation

1999 • 474 citations

Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice.

1997 • 455 citations

Development of a Natural Model of Cutaneous Leishmaniasis: Powerful Effects of Vector Saliva and Saliva Preexposure on the Long-Term Outcome of Leishmania major Infection in the Mouse Ear Dermis

1998 • 409 citations

Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells.

1994 • 379 citations

Chemokines: signal lamps for trafficking of T and B cells for development and effector function

1999 • 348 citations

Chemokine Up-Regulation and Activated T Cell Attraction by Maturing Dendritic Cells

1999 • 315 citations

Dendritic cells capable of stimulating T cells in germinal centres

1996 • 309 citations

Molecular Cloning of a Novel T Cell-directed CC Chemokine Expressed in Thymus by Signal Sequence Trap Using Epstein-Barr Virus Vector

1996 • 304 citations

Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen‐specific T cells

1993 • 276 citations

Heterogeneity of Mouse Spleen Dendritic Cells: In Vivo Phagocytic Activity, Expression of Macrophage Markers, and Subpopulation Turnover

1998 • 261 citations

CCR5 Binds Multiple CC-Chemokines: MCP-3 Acts as a Natural Antagonist

1999 • 252 citations

Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling.

1999 • 249 citations

CCR5 Binds Multiple CC-Chemokines: MCP-3 Acts as a Natural Antagonist

1999 • 239 citations

Dendritic cells and the initiation of contact sensitivity to fluorescein isothiocyanate.

1986 • 221 citations

Dendritic Cell Development: Multiple Pathways to Nature's Adjuvants

1997 • 217 citations

Differences Between IL-4- and IL-4 Receptor α-Deficient Mice in Chronic Leishmaniasis Reveal a Protective Role for IL-13 Receptor Signaling

1999 • 204 citations

The Role of CCR7 in T _H 1 and T _H 2 Cell Localization and Delivery of B Cell Help in Vivo

1999 • 181 citations

Dendritic cells in Leishmania major‐immune mice harbor persistent parasites and mediate an antigen‐specific T cell immune response

1995 • 172 citations

In susceptible mice, Leishmania major induce very rapid interleukin‐4 production by CD4⁺ T cells which are NK1.1⁻

1995 • 168 citations

Defects in the generation of IFN-gamma are overcome to control infection with Leishmania donovani in CC chemokine receptor (CCR) 5-, macrophage inflammatory protein-1 alpha-, or CCR2-deficient mice.

1999 • 163 citations

IL-4- and IL-4 Receptor-Deficient BALB/c Mice Reveal Differences in Susceptibility to Leishmania major Parasite Substrains

1999 • 156 citations

Cutaneous leishmaniasis in anti-IgM-treated mice: enhanced resistance due to functional depletion of a B cell-dependent T cell involved in the suppressor pathway.

1984 • 153 citations

The IL-4 rapidly produced in BALB/c mice after infection with Leishmania major down-regulates IL-12 receptor beta 2-chain expression on CD4+ T cells resulting in a state of unresponsiveness to IL-12.

1998 • 151 citations

Differential responsiveness to constitutive vs. inducible chemokines of immature and mature mouse dendritic cells

1999 • 150 citations

Dendritic Cell (DC)-Based Anti-Infective Strategies: DCs Engineered to Secrete IL-12 Are a Potent Vaccine in a Murine Model of an Intracellular Infection

1999 • 140 citations

The Role of Chemokines in Regulating Cell Migration during Humoral Immune Responses

1999 • 133 citations

Defects in the Generation of IFN-γ Are Overcome to Control Infection withLeishmania donovaniin CC Chemokine Receptor (CCR) 5-, Macrophage Inflammatory Protein-1α-, or CCR2-Deficient Mice

1999 • 131 citations

Animal Models for the Analysis of Immune Responses to Leishmaniasis

1998 • 124 citations

Differences in the onset of the inflammatory response to cutaneous leishmaniasis in resistant and susceptible mice

1992 • 124 citations

Leukocyte migration: Scent of the T zone

2000 • 116 citations

Effect of C-C Chemokine Receptor 2 (CCR2) Knockout on Type-2 (Schistosomal Antigen-Elicited) Pulmonary Granuloma Formation

1999 • 112 citations

The IL-4 Rapidly Produced in BALB/c Mice After Infection with Leishmania major Down-Regulates IL-12 Receptor β2-Chain Expression on CD4+ T Cells Resulting in a State of Unresponsiveness to IL-12

1998 • 112 citations

B-Cell Outgrowth and Ligand-Specific Production of IL-10 Correlate with Th2 Dominance in Certain Parasitic Diseases

1996 • 98 citations

Interleukin‐4 transgenic mice of resistant background are susceptible to Leishmania major infection

1993 • 95 citations

Interpretation of phenotype in genetically engineered mice.

1999 • 95 citations

Mouse models of human genetic disease: Which mouse is more like a man?

1996 • 91 citations

Chemokines and B-cell Homing to Follicles

1999 • 78 citations

Contribution of Dermal Macrophage Trafficking in the Sensitization Phase of Contact Hypersensitivity

1998 • 74 citations

A method to recover, enumerate and identify lymphomyeloid cells present in an inflammatory dermal site: a study in laboratory mice

1996 • 67 citations

Systemic migration of dendritic cells during contact sensitization.

1990 • 63 citations

TH1 and TH2 T-cell subsets are differentially activated by macrophages and B cells in murine leishmaniasis

1993 • 58 citations

Profile of human T cell response to leishmanial antigens. Analysis by immunoblotting.

1989 • 58 citations

Langerhans cells acquire a CD8+ dendritic cell phenotype on maturation by CD40 ligation

2000 • 57 citations

Distribution of immunogenic cells after painting with the contact sensitizers fluorescein isothiocyanate and oxazolone. Different sensitizers form immunogenic complexes with different cell populations.

1980 • 53 citations

Accessory functions and mutual cooperation of murine macrophages and dendritic cells

1983 • 39 citations

Host susceptibility factors to cutaneous leishmaniasis

1998 • 36 citations

Natural and induced regulation of Th1/Th2 balance

1999 • 20 citations