Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: Enhancement by angiotensin II

Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

1996 • 2,456 citations

Mitogenic Signaling Mediated by Oxidants in Ras-Transformed Fibroblasts

1997 • 1,582 citations

Role of Superoxide in Angiotensin II–Induced but Not Catecholamine-Induced Hypertension

1997 • 831 citations

p22 Is a Critical Component of the Superoxide-generating NADH/NADPH Oxidase System and Regulates Angiotensin IIinduced Hypertrophy in Vascular Smooth Muscle Cells

1996 • 768 citations

Regulation of Phagocyte Oxygen Radical Production by the GTP-Binding Protein Rac 2

1991 • 669 citations

Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression.

1992 • 653 citations

A Novel Role for the β2 Integrin CD11b/CD18 in Neutrophil Apoptosis: A Homeostatic Mechanism in Inflammation

1996 • 645 citations

Modulation of fibroblast proliferation by oxygen free radicals

1990 • 617 citations

NADH oxidoreductase is a major source of superoxide anion in bovine coronary artery endothelium

1994 • 546 citations

Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins

1996 • 534 citations

Myofibroblasts differentiate from fibroblasts when plated at low density.

1996 • 482 citations

Expression of phagocyte NADPH oxidase components in human endothelial cells

1996 • 432 citations

Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase.

1996 • 381 citations

Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutase activity

1991 • 322 citations

An NADPH oxidase superoxide-generating system in the rabbit aorta

1995 • 295 citations

Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathway.

1994 • 254 citations

Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits.

1994 • 229 citations

Lucigenin (Bis-N-methylacridinium) as a Mediator of Superoxide Anion Production

1997 • 220 citations

NADPH oxidase of neutrophils

1996 • 208 citations

Dietary antioxidants preserve endothelium-dependent vessel relaxation in cholesterol-fed rabbits.

1993 • 204 citations

Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation.

1995 • 202 citations

Sites of superoxide anion production detected by lucigenin in calf pulmonary artery smooth muscle

1994 • 165 citations

Topological Mapping of Neutrophil Cytochrome b Epitopes with Phage-display Libraries

1995 • 162 citations

Functional expression of NADPH oxidase components (alpha- and beta-subunits of cytochrome b558 and 45-kDa flavoprotein) by intrinsic human glomerular mesangial cells.

1991 • 146 citations

Differential gene expression and regulation of type-1 angiotensin II receptor subtypes in the rat

1992 • 146 citations

Hydrogen peroxide-induced c-fos expression is mediated by arachidonic acid release: role of protein kinase C

1993 • 137 citations

Assembly of the Human Neutrophil NADPH Oxidase Involves Binding of p67 and Flavocytochrome to a Common Functional Domain in p47

1996 • 124 citations

The cytochrome b-558 molecules involved in the fibroblast and polymorphonuclear leucocyte superoxide-generating NADPH oxidase systems are structurally and genetically distinct

1993 • 119 citations

Chronic control of high blood pressure in the spontaneously hypertensive rat by delivery of angiotensin type 1 receptor antisense.

1996 • 105 citations

The formation and biologic significance of phagocyte-derived oxidants.

1995 • 91 citations

Salicylate or Aspirin Inhibits the Induction of the Inducible Nitric Oxide Synthase in Rat Cardiac Fibroblasts

1996 • 91 citations

Angiotensin II-induced cardiac fibrosis in the rat is increased by chronic inhibition of nitric oxide synthase.

1995 • 87 citations

Indications to an NADPH oxidase as a possible pO₂ sensor in the rat carotid body

1989 • 83 citations

Genomic structure, chromosomal localization, start of transcription, and tissue expression of the human p40-phox, a new component of the nicotinamide adenine dinucleotide phosphate-oxidase complex

1996 • 76 citations

Increased type I collagen mRNA levels in cultured scleroderma fibroblasts

1984 • 76 citations

The adventitia may be a barrier specific to nitric oxide in rabbit pulmonary artery.

1994 • 53 citations

Effects of Angiotensin II Infusion and Inhibition of Nitric Oxide Synthase on the Rat Aorta

1996 • 45 citations

Inhibition of relaxations to nitrergic stimulation of the mouse anococcygeus by duroquinone

1995 • 40 citations

Stabilization of human neutrophil NADPH oxidase activated in a cell-free system by cytosolic proteins and by 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide.

1992 • 34 citations

The use of diphenylene iodonium, an inhibitor of NADPH oxidase, to investigate the antimicrobial action of human monocyte derived macrophages

1990 • 33 citations

Angiotensin and bradykinin metabolism by peptidases identified in cultured human skeletal muscle myocytes and fibroblasts

1995 • 30 citations

Vitamin Ε Reduces Bleomycin-Induced Lung Fibrosis in Mice: Biochemical and Morphological Studies

1993 • 30 citations

Aminopeptidase N: A Constitutive Cell-Surface Protein on Human Dermal Fibroblasts

1995 • 29 citations

Identification of a thermolabile component of the human neutrophil NADPH oxidase. A model for chronic granulomatous disease caused by deficiency of the p67-phox cytosolic component.

1992 • 27 citations

Antioxidant therapy partially blocks immune-induced lung fibrosis

1995 • 24 citations

Differences and similarities between human and rabbit neutrophil granulocyte responses in vitro: the effects of zymosan‐activated plasma, phorbol myristate acetate and n‐formyl‐methionyl‐leucyl‐phenylalanine

1987 • 23 citations

Inhibition of NO‐mediated responses by 7‐ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P₄₅₀

1996 • 16 citations

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